Unreviewed, UniProtKB/TrEMBL Q6XV46 (Q6XV46_9INFA)

Names and origin

Protein names

Submitted name:
    Neuraminidase EMBL AAO62044.1

Gene names

Name:

NA EMBL AAO62044.1

Organism

Influenza A virus (A/mink/Sweden/E12665/84(H10N4)) EMBL AAO62044.1

Taxonomic identifier

222742 [NCBI]

Taxonomic lineage

Viruses › ssRNA negative-strand viruses › Orthomyxoviridae › Influenzavirus A

Protein attributes

Sequence length	470 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. Spearmint SPM001860
Subunit structure	Homotetramer By similarity. Spearmint SPM001860

Ontologies

Keywords
Cellular component	Cell membrane Spearmint SPM001860 Membrane Virion Spearmint SPM001860
Domain	Transmembrane Spearmint SPM001860
Molecular function	Glycosidase Spearmint SPM001860 Hydrolase
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	apical plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW virion membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	exo-alpha-sialidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6XV46-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: B63040295F04643C	FASTA	470	51,848
	10 20 30 40 50 60 MNPNQKIITI GSVSIVLTTI GLLLQITSLC SIWFSHYNQV TQTNEQPCSN NTTNYYNETF 70 80 90 100 110 120 VNVTNVQNNY TTITDPSTSQ VIHYSSGKDL CPVKGWAPLS KDNGIRIGSR GEVFVIREPF 130 140 150 160 170 180 ISCSINECRT FFLTQGALLN DKHSNGTVKD RSPFRTLMSC PIGVAPSPSN SRFESVAWSA 190 200 210 220 230 240 TACSDGPGWL TIGITGPDAT AVAVLKYNGI ITDTLKSWKG NIMRTQESEC VCQDEFCYTL 250 260 270 280 290 300 ITDGPSDAQA FYKILKIKKG KIVSVKDVDA PGFHFEECSC YPSGENVECV CRDNWRGSNR 310 320 330 340 350 360 PWIRFNSDLD YQIGYVCSGV FGDNPRPMDS TGSCNSPINN GKGRYGVKGF SFRYGDGVWI 370 380 390 400 410 420 GRTKSLESRS GFEMVWDANG WVSTDKDSNG VQDIIDNDNW SGYSGSFSIR GETTGRNCTV 430 440 450 460 470 PCFWVEMIRG QPKEKTIWTS GSSIAFCGVN SDTTGWSWPD GALLPFDIDK

References

[1]	"Genetic analysis of multiple N3, N4, and N6 influenza A virus neuraminidase genes." Webby R.J., Humberd J.L., Krauss S.L. Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: A/mink/Sweden/E12665/84 EMBL AAO62044.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

AY207530 Genomic DNA. Translation: AAO62044.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2HTV	X-ray	2.80	A/B	81-470	[»]
2HTW	X-ray	3.50	A	81-470	[»]

ModBase

Search...

Protein family/group databases

CAZy

GH34. Glycoside Hydrolase Family 34.

Family and domain databases

InterPro

IPR001860. Glyco_hydro_34.
[Graphical view]

Pfam

PF00064. Neur. 1 hit.
[Graphical view]

ProDom

PD000431. Glyco_hydro_34. 1 hit.
[Graphical view] [Entries sharing at least one domain]

ProtoNet

Search...

Entry information

Entry name

Q6XV46_9INFA

Accession

Primary (citable) accession number: Q6XV46

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 5, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)