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Q6XNL5

- RDRP_MRNV

UniProt

Q6XNL5 - RDRP_MRNV

Protein

RNA-directed RNA polymerase

Gene
N/A
Organism
Macrobrachium rosenbergii nodavirus (MrNV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 AND RNA2.Curated

    Catalytic activityi

    Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

    GO - Molecular functioni

    1. RNA binding Source: InterPro
    2. RNA-directed RNA polymerase activity Source: UniProtKB-KW

    GO - Biological processi

    1. transcription, DNA-templated Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA-directed RNA polymerase (EC:2.7.7.48)
    Short name:
    RdRp
    Alternative name(s):
    RNA replicase
    OrganismiMacrobrachium rosenbergii nodavirus (MrNV)
    Taxonomic identifieri222557 [NCBI]
    Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeunclassified Nodaviridae
    Virus hostiMacrobrachium rosenbergii (Giant fresh water prawn) [TaxID: 79674]

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10451045RNA-directed RNA polymerasePRO_0000223687Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ6XNL5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini593 – 718126RdRp catalyticAdd
    BLAST

    Sequence similaritiesi

    Belongs to the nodaviridae RNA polymerase family.Curated
    Contains 1 RdRp catalytic domain.Curated

    Family and domain databases

    InterProiIPR001205. RNA-dir_pol_C.
    [Graphical view]
    PfamiPF00680. RdRP_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6XNL5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKCNNLLYGV ELPMCLQSSM GMVVVTGLAI VYLVIYILIY SFTHGPRLSR     50
    RLASYVVIGP YEAIAKSRPA MALQRAMVDL TRRDVRTDWY PLNNLLMNKP 100
    HRLSENGHKT SGAVRDAARN LITSAITSLG MDKYEISPGG HTVDEQLASH 150
    RHYAVNDLHR ASADDAVKEN AVIVAIDTDY YLRDPSIYFS NNNPFILHTF 200
    QPITVAGKDG DVRFTISDNQ VDYRVDGGGR WQHKVWNWCD YGEFLYLKNI 250
    LGILSINWWL SFFGIRKVIY QKIQHARPWV DCPNRALVWG LPQFTRYMIT 300
    WLPIEMNARE LSRVNYQCAS RPGWNCLVDH TSTKLVASIG REGNDCHVEL 350
    AKEDLDVVLG LSTMQSVTSR LLQMGYKQPQ TLATVCQFYN SAAYDILSCS 400
    IVARPSQPPV HWPLASEIDQ PTTSFRNYSN NIVTCGNLCP QLKRWEVLSN 450
    SLEHRVTMVA NNKVPTPRIA RFAEEYVRLV VPEANVGVPY SLEDARKELD 500
    KPTQVNAVNQ IWETVDMEVR RLIEAFVKNE PTNKSGRIIS SFADSRFLLK 550
    FSTYTLAFRD EVLHAEHNRH WFCPGLTPNE IADKVCDYVR GVATPAEGDF 600
    SNFDGRVSAW CQENVMNAVY HRWFNRKFSK ELQKYTSMLV SCPARAKRFG 650
    FQYEPGVGVK SGSPTTCDLN SVLNNFTQYA AVRLTKPDLS PQEAFEQTGL 700
    SFGDDSLFDK QYQLRWNYVV EQLGMELKVE PFDPSNGVTF LARVFPDPYS 750
    TNTSFQDPLR TWRKLNMTSR TCVPVESAAL DRVSGYLVTD KYSPVTSEYC 800
    HMIERCYMNT AESVTRRRQR KDCDREKPYW LVSGGAWPQR EGDYELMMRV 850
    TAARTGFEES KLINLISQFQ SVHDPWDIKP LDYQEPSPYK DTLDIDGQPV 900
    DAVDERQYQN ERNTVNLRAG AAISQMPVPS VPGGEDCNRQ SADMPGPKSS 950
    EGSEQLQGLP EQDGSNRLQC HRQPTFKAKG GSNTKGRSRK SRNGGRSISS 1000
    KTANPTTHEV GGGNGKTRVT IAKRSGPKRP HNVVSNAWET LNDNR 1045
    Length:1,045
    Mass (Da):118,394
    Last modified:July 5, 2004 - v1
    Checksum:i229E7D36C9376032
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY222839 Genomic RNA. Translation: AAO60068.1.
    RefSeqiNP_919036.1. NC_005094.1.

    Genome annotation databases

    GeneIDi2943295.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY222839 Genomic RNA. Translation: AAO60068.1 .
    RefSeqi NP_919036.1. NC_005094.1.

    3D structure databases

    ProteinModelPortali Q6XNL5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2943295.

    Family and domain databases

    InterProi IPR001205. RNA-dir_pol_C.
    [Graphical view ]
    Pfami PF00680. RdRP_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the MrNV-RNA-1 of Macrobrachium rosenbergii."
      Bonami J.-R., Sri Widada J., Richard V.R., Vincent A., Durand S.P.
      Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiRDRP_MRNV
    AccessioniPrimary (citable) accession number: Q6XNL5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 21, 2006
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3