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Q6XNL5

- RDRP_MRNV

UniProt

Q6XNL5 - RDRP_MRNV

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Protein

RNA-directed RNA polymerase

Gene
N/A
Organism
Macrobrachium rosenbergii nodavirus (MrNV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 AND RNA2 Reviewed prediction.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. RNA-directed RNA polymerase activity Source: UniProtKB-KW

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-directed RNA polymerase (EC:2.7.7.48)
Short name:
RdRp
Alternative name(s):
RNA replicase
OrganismiMacrobrachium rosenbergii nodavirus (MrNV)
Taxonomic identifieri222557 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeunclassified Nodaviridae
Virus hostiMacrobrachium rosenbergii (Giant fresh water prawn) [TaxID: 79674]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10451045RNA-directed RNA polymerasePRO_0000223687Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ6XNL5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini593 – 718126RdRp catalyticAdd
BLAST

Sequence similaritiesi

Family and domain databases

InterProiIPR001205. RNA-dir_pol_C.
[Graphical view]
PfamiPF00680. RdRP_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6XNL5-1 [UniParc]FASTAAdd to Basket

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MKCNNLLYGV ELPMCLQSSM GMVVVTGLAI VYLVIYILIY SFTHGPRLSR     50
RLASYVVIGP YEAIAKSRPA MALQRAMVDL TRRDVRTDWY PLNNLLMNKP 100
HRLSENGHKT SGAVRDAARN LITSAITSLG MDKYEISPGG HTVDEQLASH 150
RHYAVNDLHR ASADDAVKEN AVIVAIDTDY YLRDPSIYFS NNNPFILHTF 200
QPITVAGKDG DVRFTISDNQ VDYRVDGGGR WQHKVWNWCD YGEFLYLKNI 250
LGILSINWWL SFFGIRKVIY QKIQHARPWV DCPNRALVWG LPQFTRYMIT 300
WLPIEMNARE LSRVNYQCAS RPGWNCLVDH TSTKLVASIG REGNDCHVEL 350
AKEDLDVVLG LSTMQSVTSR LLQMGYKQPQ TLATVCQFYN SAAYDILSCS 400
IVARPSQPPV HWPLASEIDQ PTTSFRNYSN NIVTCGNLCP QLKRWEVLSN 450
SLEHRVTMVA NNKVPTPRIA RFAEEYVRLV VPEANVGVPY SLEDARKELD 500
KPTQVNAVNQ IWETVDMEVR RLIEAFVKNE PTNKSGRIIS SFADSRFLLK 550
FSTYTLAFRD EVLHAEHNRH WFCPGLTPNE IADKVCDYVR GVATPAEGDF 600
SNFDGRVSAW CQENVMNAVY HRWFNRKFSK ELQKYTSMLV SCPARAKRFG 650
FQYEPGVGVK SGSPTTCDLN SVLNNFTQYA AVRLTKPDLS PQEAFEQTGL 700
SFGDDSLFDK QYQLRWNYVV EQLGMELKVE PFDPSNGVTF LARVFPDPYS 750
TNTSFQDPLR TWRKLNMTSR TCVPVESAAL DRVSGYLVTD KYSPVTSEYC 800
HMIERCYMNT AESVTRRRQR KDCDREKPYW LVSGGAWPQR EGDYELMMRV 850
TAARTGFEES KLINLISQFQ SVHDPWDIKP LDYQEPSPYK DTLDIDGQPV 900
DAVDERQYQN ERNTVNLRAG AAISQMPVPS VPGGEDCNRQ SADMPGPKSS 950
EGSEQLQGLP EQDGSNRLQC HRQPTFKAKG GSNTKGRSRK SRNGGRSISS 1000
KTANPTTHEV GGGNGKTRVT IAKRSGPKRP HNVVSNAWET LNDNR 1045
Length:1,045
Mass (Da):118,394
Last modified:July 5, 2004 - v1
Checksum:i229E7D36C9376032
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY222839 Genomic RNA. Translation: AAO60068.1.
RefSeqiNP_919036.1. NC_005094.1.

Genome annotation databases

GeneIDi2943295.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY222839 Genomic RNA. Translation: AAO60068.1 .
RefSeqi NP_919036.1. NC_005094.1.

3D structure databases

ProteinModelPortali Q6XNL5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2943295.

Family and domain databases

InterProi IPR001205. RNA-dir_pol_C.
[Graphical view ]
Pfami PF00680. RdRP_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence of the MrNV-RNA-1 of Macrobrachium rosenbergii."
    Bonami J.-R., Sri Widada J., Richard V.R., Vincent A., Durand S.P.
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiRDRP_MRNV
AccessioniPrimary (citable) accession number: Q6XNL5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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