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Q6XNL5 (RDRP_MRNV) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA-directed RNA polymerase

Short name=RdRp
EC=2.7.7.48
Alternative name(s):
RNA replicase
OrganismMacrobrachium rosenbergii nodavirus (MrNV)
Taxonomic identifier222557 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeunclassified Nodaviridae
Virus hostMacrobrachium rosenbergii (Giant fresh water prawn) [TaxID: 79674]

Protein attributes

Sequence length1045 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 AND RNA2 Potential.

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Sequence similarities

Belongs to the nodaviridae RNA polymerase family.

Contains 1 RdRp catalytic domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10451045RNA-directed RNA polymerase
PRO_0000223687

Regions

Domain593 – 718126RdRp catalytic

Sequences

Sequence LengthMass (Da)Tools
Q6XNL5 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 229E7D36C9376032

FASTA1,045118,394
        10         20         30         40         50         60 
MKCNNLLYGV ELPMCLQSSM GMVVVTGLAI VYLVIYILIY SFTHGPRLSR RLASYVVIGP 

        70         80         90        100        110        120 
YEAIAKSRPA MALQRAMVDL TRRDVRTDWY PLNNLLMNKP HRLSENGHKT SGAVRDAARN 

       130        140        150        160        170        180 
LITSAITSLG MDKYEISPGG HTVDEQLASH RHYAVNDLHR ASADDAVKEN AVIVAIDTDY 

       190        200        210        220        230        240 
YLRDPSIYFS NNNPFILHTF QPITVAGKDG DVRFTISDNQ VDYRVDGGGR WQHKVWNWCD 

       250        260        270        280        290        300 
YGEFLYLKNI LGILSINWWL SFFGIRKVIY QKIQHARPWV DCPNRALVWG LPQFTRYMIT 

       310        320        330        340        350        360 
WLPIEMNARE LSRVNYQCAS RPGWNCLVDH TSTKLVASIG REGNDCHVEL AKEDLDVVLG 

       370        380        390        400        410        420 
LSTMQSVTSR LLQMGYKQPQ TLATVCQFYN SAAYDILSCS IVARPSQPPV HWPLASEIDQ 

       430        440        450        460        470        480 
PTTSFRNYSN NIVTCGNLCP QLKRWEVLSN SLEHRVTMVA NNKVPTPRIA RFAEEYVRLV 

       490        500        510        520        530        540 
VPEANVGVPY SLEDARKELD KPTQVNAVNQ IWETVDMEVR RLIEAFVKNE PTNKSGRIIS 

       550        560        570        580        590        600 
SFADSRFLLK FSTYTLAFRD EVLHAEHNRH WFCPGLTPNE IADKVCDYVR GVATPAEGDF 

       610        620        630        640        650        660 
SNFDGRVSAW CQENVMNAVY HRWFNRKFSK ELQKYTSMLV SCPARAKRFG FQYEPGVGVK 

       670        680        690        700        710        720 
SGSPTTCDLN SVLNNFTQYA AVRLTKPDLS PQEAFEQTGL SFGDDSLFDK QYQLRWNYVV 

       730        740        750        760        770        780 
EQLGMELKVE PFDPSNGVTF LARVFPDPYS TNTSFQDPLR TWRKLNMTSR TCVPVESAAL 

       790        800        810        820        830        840 
DRVSGYLVTD KYSPVTSEYC HMIERCYMNT AESVTRRRQR KDCDREKPYW LVSGGAWPQR 

       850        860        870        880        890        900 
EGDYELMMRV TAARTGFEES KLINLISQFQ SVHDPWDIKP LDYQEPSPYK DTLDIDGQPV 

       910        920        930        940        950        960 
DAVDERQYQN ERNTVNLRAG AAISQMPVPS VPGGEDCNRQ SADMPGPKSS EGSEQLQGLP 

       970        980        990       1000       1010       1020 
EQDGSNRLQC HRQPTFKAKG GSNTKGRSRK SRNGGRSISS KTANPTTHEV GGGNGKTRVT 

      1030       1040 
IAKRSGPKRP HNVVSNAWET LNDNR 

« Hide

References

[1]"Nucleotide sequence of the MrNV-RNA-1 of Macrobrachium rosenbergii."
Bonami J.-R., Sri Widada J., Richard V.R., Vincent A., Durand S.P.
Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY222839 Genomic RNA. Translation: AAO60068.1.
RefSeqNP_919036.1. NC_005094.1.

3D structure databases

ProteinModelPortalQ6XNL5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2943295.

Family and domain databases

InterProIPR001205. RNA-dir_pol_C.
[Graphical view]
PfamPF00680. RdRP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRDRP_MRNV
AccessionPrimary (citable) accession number: Q6XNL5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families