ID   MATPI_SCHKA             Reviewed;         159 AA.
AC   Q6WRX8;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   RecName: Full=Mating-type P-specific polypeptide Pi;
GN   Name=matPi;
OS   Schizosaccharomyces kambucha (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=204045;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=14618565; DOI=10.1002/yea.1042;
RA   Singh G., Klar A.J.S.;
RT   "DNA sequence of the mat2,3 region of Schizosaccharomyces kambucha shares
RT   high homology with the corresponding sequence from Sz. pombe.";
RL   Yeast 20:1273-1278(2003).
CC   -!- FUNCTION: Mating type proteins are sequence specific DNA-binding
CC       proteins that act as master switches in yeast differentiation by
CC       controlling gene expression in a cell type-specific fashion. Required
CC       for meiosis, but plays no role in conjugation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC   -!- MISCELLANEOUS: There are three genetic loci for mating type genes in
CC       fission yeast, mat1, mat2-P and mat3-M. Cell type is determined by the
CC       alternate allele present in mat1, either P (plus) in a h+ or M (minus)
CC       in a h- cell. Mat2-P and mat3-M serve as donor of information that is
CC       transposed to mat1 during a switch of mating type (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TALE/M-ATYP homeobox family. {ECO:0000305}.
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DR   EMBL; AY271822; AAQ82720.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6WRX8; -.
DR   SMR; Q6WRX8; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   PANTHER; PTHR11850:SF102; HOMEOBOX PROTEIN HOMOTHORAX; 1.
DR   PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Homeobox; Nucleus.
FT   CHAIN           1..159
FT                   /note="Mating-type P-specific polypeptide Pi"
FT                   /id="PRO_0000049408"
FT   DNA_BIND        103..159
FT                   /note="Homeobox; TALE-type; partial"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
SQ   SEQUENCE   159 AA;  18671 MW;  226371B0446AE8EA CRC64;
     MKRVAVLLKT VMCEFLKCDY NGYDRIISLL RRILTLICTP NLNGLTIKRV IDSMQSLEYI
     KQTCNFKLQM CISSMAFKRN NALQNCNHYA WCDDHCSDIG RPMTTVRGQC SKCTKPHLMR
     WLLLHYDNPY PSNSEFYDLS AATGLTRTQL RNWFSNRRR
//