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Q6WRX8

- MATPI_SCHKA

UniProt

Q6WRX8 - MATPI_SCHKA

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Protein

Mating-type P-specific polypeptide Pi

Gene

matPi

Organism
Schizosaccharomyces kambucha (Fission yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Required for meiosis, but plays no role in conjugation (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi103 – 15957Homeobox; TALE-type; partialPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mating-type P-specific polypeptide Pi
Gene namesi
Name:matPi
OrganismiSchizosaccharomyces kambucha (Fission yeast)
Taxonomic identifieri204045 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Subcellular locationi

Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 159159Mating-type P-specific polypeptide PiPRO_0000049408Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ6WRX8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TALE/M-ATYP homeobox family.Curated
Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF05920. Homeobox_KN. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6WRX8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKRVAVLLKT VMCEFLKCDY NGYDRIISLL RRILTLICTP NLNGLTIKRV
60 70 80 90 100
IDSMQSLEYI KQTCNFKLQM CISSMAFKRN NALQNCNHYA WCDDHCSDIG
110 120 130 140 150
RPMTTVRGQC SKCTKPHLMR WLLLHYDNPY PSNSEFYDLS AATGLTRTQL

RNWFSNRRR
Length:159
Mass (Da):18,671
Last modified:July 5, 2004 - v1
Checksum:i226371B0446AE8EA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY271822 Genomic DNA. Translation: AAQ82720.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY271822 Genomic DNA. Translation: AAQ82720.1 .

3D structure databases

ProteinModelPortali Q6WRX8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
[Graphical view ]
Pfami PF05920. Homeobox_KN. 1 hit.
[Graphical view ]
SMARTi SM00389. HOX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS50071. HOMEOBOX_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "DNA sequence of the mat2,3 region of Schizosaccharomyces kambucha shares high homology with the corresponding sequence from Sz. pombe."
    Singh G., Klar A.J.S.
    Yeast 20:1273-1278(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiMATPI_SCHKA
AccessioniPrimary (citable) accession number: Q6WRX8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

There are three genetic loci for mating type genes in fission yeast, mat1, mat2-P and mat3-M. Cell type is determined by the alternate allele present in mat1, either P (plus) in an h+ or M (minus) in an h- cell. Mat2-P and mat3-M serve as donor of information that is transposed to mat1 during a switch of mating type (By similarity).By similarity

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3