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Q6WRX8 (MATPI_SCHKA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mating-type P-specific polypeptide Pi
Gene names
Name:matPi
OrganismSchizosaccharomyces kambucha (Fission yeast)
Taxonomic identifier204045 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length159 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Required for meiosis, but plays no role in conjugation By similarity.

Subcellular location

Nucleus Potential.

Miscellaneous

There are three genetic loci for mating type genes in fission yeast, mat1, mat2-P and mat3-M. Cell type is determined by the alternate allele present in mat1, either P (plus) in an h+ or M (minus) in an h- cell. Mat2-P and mat3-M serve as donor of information that is transposed to mat1 during a switch of mating type By similarity.

Sequence similarities

Belongs to the TALE/M-ATYP homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 159159Mating-type P-specific polypeptide Pi
PRO_0000049408

Regions

DNA binding103 – 15957Homeobox; TALE-type; partial

Sequences

Sequence LengthMass (Da)Tools
Q6WRX8 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 226371B0446AE8EA

FASTA15918,671
        10         20         30         40         50         60 
MKRVAVLLKT VMCEFLKCDY NGYDRIISLL RRILTLICTP NLNGLTIKRV IDSMQSLEYI 

        70         80         90        100        110        120 
KQTCNFKLQM CISSMAFKRN NALQNCNHYA WCDDHCSDIG RPMTTVRGQC SKCTKPHLMR 

       130        140        150 
WLLLHYDNPY PSNSEFYDLS AATGLTRTQL RNWFSNRRR 

« Hide

References

[1]"DNA sequence of the mat2,3 region of Schizosaccharomyces kambucha shares high homology with the corresponding sequence from Sz. pombe."
Singh G., Klar A.J.S.
Yeast 20:1273-1278(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY271822 Genomic DNA. Translation: AAQ82720.1.

3D structure databases

ProteinModelPortalQ6WRX8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.10.60. 1 hit.
InterProIPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
[Graphical view]
PfamPF05920. Homeobox_KN. 1 hit.
[Graphical view]
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMATPI_SCHKA
AccessionPrimary (citable) accession number: Q6WRX8
Entry history
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families