Q6WRX8 (MATPI_SCHKA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Mating-type P-specific polypeptide Pi

Gene names

Name:

matPi

Organism

Schizosaccharomyces kambucha (Fission yeast)

Taxonomic identifier

204045 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	159 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Required for meiosis, but plays no role in conjugation By similarity.
Subcellular location	Nucleus Potential.
Miscellaneous	There are three genetic loci for mating type genes in fission yeast, mat1, mat2-P and mat3-M. Cell type is determined by the alternate allele present in mat1, either P (plus) in an h+ or M (minus) in an h- cell. Mat2-P and mat3-M serve as donor of information that is transposed to mat1 during a switch of mating type By similarity.
Sequence similarities	Belongs to the TALE/M-ATYP homeobox family. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 159	159	Mating-type P-specific polypeptide Pi		PRO_0000049408
Regions
	DNA binding	103 – 159	57	Homeobox; TALE-type; partial

Sequences

	Sequence		Length	Mass (Da)
	Q6WRX8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 226371B0446AE8EA	FASTA	159	18,671
	10 20 30 40 50 60 MKRVAVLLKT VMCEFLKCDY NGYDRIISLL RRILTLICTP NLNGLTIKRV IDSMQSLEYI 70 80 90 100 110 120 KQTCNFKLQM CISSMAFKRN NALQNCNHYA WCDDHCSDIG RPMTTVRGQC SKCTKPHLMR 130 140 150 WLLLHYDNPY PSNSEFYDLS AATGLTRTQL RNWFSNRRR

References

[1]	"DNA sequence of the mat2,3 region of Schizosaccharomyces kambucha shares high homology with the corresponding sequence from Sz. pombe." Singh G., Klar A.J.S. Yeast 20:1273-1278(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY271822 Genomic DNA. Translation: AAQ82720.1.
3D structure databases
ProteinModelPortal	Q6WRX8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.10.60. 1 hit.
InterPro	IPR008422. Homeobox_KN_domain. IPR001356. Homeodomain. IPR009057. Homeodomain-like. [Graphical view]
Pfam	PF05920. Homeobox_KN. 1 hit. [Graphical view]
SMART	SM00389. HOX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. False negative. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MATPI_SCHKA

Accession

Primary (citable) accession number: Q6WRX8

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 31, 2004
Last sequence update:	July 5, 2004
Last modified:	March 6, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program