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Q6WRI4 (Q6WRI4_LEIMA) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Aromatic amino acid hydroxylase-like EMBL AAQ02690.1
Submitted name:
Phenylalanine-4-hydroxylase EMBL CAJ05368.1
EC=1.14.16.1 EMBL CAJ05368.1
Gene names
Name:AAAHL EMBL AAQ02690.1
Synonyms:PAH EMBL CAJ05368.1
ORF Names:LMJF_28_1280 EMBL CAJ05368.1
OrganismLeishmania major EMBL AAQ02690.1
Taxonomic identifier5664 [NCBI]
Taxonomic lineageEukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania

Protein attributes

Sequence length453 AA.
Sequence statusComplete.
Protein existencePredicted

Sequences

Sequence LengthMass (Da)Tools
Q6WRI4 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 2FAE2F9988269D05

FASTA45351,454
        10         20         30         40         50         60 
MLLRSRLFLE AGMAAAAATL KAQYASPGSN IKGADKKTRC RTSLQVSLST DKPGELCHLL 

        70         80         90        100        110        120 
SVFKPYSINI SQVANRPRAY ENKAPLRTIF LDVDAYIEDE SMKKVMAELH AKFPNVVVTG 

       130        140        150        160        170        180 
SWVIPWYPTE PKDLDELDQS TLAAGEELQE DPENPHPGFH DEVYRARRRE IVGLAKNYKT 

       190        200        210        220        230        240 
GDPIPIVNYT EEENRVWTVV YDHLTRLYPT HACQQYNYVF PLLLENGVLS RTKTPQLRDV 

       250        260        270        280        290        300 
SEFLNEATGF TVRPVTGLLT SRDFLNALAF RVFYSTQYIR HAAQPLYTPE PDMVHDIIGH 

       310        320        330        340        350        360 
LPLLSDPDFA NFTQTIGLAS LGASDELLDK LAKVYWYSVE FGLCSEGGRR KAYGAGILSS 

       370        380        390        400        410        420 
CGELEYALSD KPECVPWDPT MASKTPFPIT KYQPLYFVAE SFSDAQRKLE AWLSSQEKPL 

       430        440        450 
YTVYNSYSRR VQSYPKNTWN MLQEQMKRTN FTF

« Hide

References

« Hide 'large scale' references
[1]"Phenylalanine hydroxylase (PAH) from the lower eukaryote Leishmania major."
Lye L.F., Kang S.O., Nosanchuk J.D., Casadevall A., Beverley S.M.
Mol. Biochem. Parasitol. 175:58-67(2010) [PubMed: 20887755] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"The genome of the kinetoplastid parasite, Leishmania major."
Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G., Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A., Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M., Bianchettin G. expand/collapse author list , Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E., Ciarloni L., Clayton C., Coulson R.M.R., Cronin A., Cruz A.K., Davies R.M., De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N., Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A., Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S., Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M., Masuy D., Matthews K., Michaeli S., Mottram J.C., Mueller-Auer S., Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M., Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E., Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C., Rutter S., Saunders D., Schaefer M., Schein J., Schwartz D.C., Seeger K., Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V., Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J., Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D., Barrell B.G., Myler P.J.
Science 309:436-442(2005) [PubMed: 16020728] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Friedlin and MHOM/IL/81/Friedlin.
[3]"Identification and characterization of aromatic amino acid hydroxylase from Leishmania major."
Lye L.-F., Beverley S.M.
Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY273788 Genomic DNA. Translation: AAQ02690.1.
FR796424 Genomic DNA. Translation: CAJ05368.1.
RefSeqXP_001684410.1. XM_001684358.1.

3D structure databases

ProteinModelPortalQ6WRI4.
SMRQ6WRI4. Positions 124-432.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsLmjF.28.1280:mRNA; LmjF.28.1280:pep; LmjF.28.1280.
GeneID5653339.
GenomeReviewsGene locus AAAHL in contig FR796424_GR.
KEGGlma:LmjF28.1280.

Organism-specific databases

EuPathDBEupathDB:LmjF.28.1280.

Phylogenomic databases

HOGENOMHBG484724.
OMAPRAYENK.
PhylomeDBQ6WRI4.
ProtClustDBCLSZ2734068.

Family and domain databases

InterProIPR001273. ArAA_hydroxylase.
IPR018301. ArAA_hydroxylase_Fe/CU_BS.
IPR019774. Aromatic-AA_hydroxylase_C.
IPR019773. Tyrosine_3-monooxygenase-like.
[Graphical view]
Gene3DG3DSA:1.10.800.10. Aaa_hydroxylase. 1 hit.
KOK00500.
PANTHERPTHR11473. Aaa_hydroxylase. 1 hit.
PfamPF00351. Biopterin_H. 1 hit.
[Graphical view]
PIRSFPIRSF000336. TH. 1 hit.
PRINTSPR00372. FYWHYDRXLASE.
SUPFAMSSF56534. Aaa_hydroxylase. 1 hit.
PROSITEPS00367. BH4_AAA_HYDROXYL_1. 1 hit.
PS51410. BH4_AAA_HYDROXYL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6WRI4_LEIMA
AccessionPrimary (citable) accession number: Q6WRI4
Secondary accession number(s): Q4Q8D8
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 16, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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