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Q6WRI0

- IGS10_HUMAN

UniProt

Q6WRI0 - IGS10_HUMAN

Protein

Immunoglobulin superfamily member 10

Gene

IGSF10

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    May be involved in the maintenance of osteochondroprogenitor cells pool.By similarity

    GO - Biological processi

    1. cell differentiation Source: UniProtKB-KW
    2. multicellular organismal development Source: UniProtKB-KW
    3. ossification Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Differentiation, Osteogenesis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Immunoglobulin superfamily member 10
    Short name:
    IgSF10
    Alternative name(s):
    Calvaria mechanical force protein 608
    Short name:
    CMF608
    Gene namesi
    Name:IGSF10
    Synonyms:CMF608
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:26384. IGSF10.

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134900760.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2828Sequence AnalysisAdd
    BLAST
    Chaini29 – 26232595Immunoglobulin superfamily member 10PRO_0000286817Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi319 – 3191N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi439 – 4391N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi497 ↔ 551PROSITE-ProRule annotation
    Disulfide bondi595 ↔ 645PROSITE-ProRule annotation
    Glycosylationi627 – 6271N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi774 – 7741N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi999 – 9991N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi1670 ↔ 1723PROSITE-ProRule annotation
    Disulfide bondi1767 ↔ 1820PROSITE-ProRule annotation
    Disulfide bondi1864 ↔ 1917PROSITE-ProRule annotation
    Glycosylationi1899 – 18991N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi1962 – 19621N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi1963 ↔ 2016PROSITE-ProRule annotation
    Disulfide bondi2060 ↔ 2119PROSITE-ProRule annotation
    Glycosylationi2101 – 21011N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi2163 ↔ 2213PROSITE-ProRule annotation
    Disulfide bondi2261 ↔ 2313PROSITE-ProRule annotation
    Disulfide bondi2359 ↔ 2411PROSITE-ProRule annotation
    Disulfide bondi2454 ↔ 2506PROSITE-ProRule annotation
    Disulfide bondi2550 ↔ 2605PROSITE-ProRule annotation
    Modified residuei2603 – 26031PhosphotyrosineBy similarity

    Keywords - PTMi

    Disulfide bond, Glycoprotein, Phosphoprotein

    Proteomic databases

    PaxDbiQ6WRI0.
    PRIDEiQ6WRI0.

    PTM databases

    PhosphoSiteiQ6WRI0.

    Expressioni

    Gene expression databases

    ArrayExpressiQ6WRI0.
    BgeeiQ6WRI0.
    CleanExiHS_IGSF10.
    GenevestigatoriQ6WRI0.

    Organism-specific databases

    HPAiHPA012921.

    Interactioni

    Protein-protein interaction databases

    BioGridi130074. 1 interaction.
    STRINGi9606.ENSP00000282466.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6WRI0.
    SMRiQ6WRI0. Positions 28-321, 490-651, 1629-2623.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini29 – 5628LRRNTAdd
    BLAST
    Repeati58 – 7922LRR 1Add
    BLAST
    Repeati82 – 10322LRR 2Add
    BLAST
    Repeati106 – 12722LRR 3Add
    BLAST
    Repeati130 – 15122LRR 4Add
    BLAST
    Repeati154 – 17522LRR 5Add
    BLAST
    Repeati186 – 20722LRR 6Add
    BLAST
    Domaini219 – 28163LRRCTAdd
    BLAST
    Domaini461 – 567107Ig-like C2-type 1Add
    BLAST
    Domaini571 – 66191Ig-like C2-type 2Add
    BLAST
    Domaini1648 – 173992Ig-like C2-type 3Add
    BLAST
    Domaini1745 – 183692Ig-like C2-type 4Add
    BLAST
    Domaini1841 – 193393Ig-like C2-type 5Add
    BLAST
    Domaini1941 – 203494Ig-like C2-type 6Add
    BLAST
    Domaini2037 – 213599Ig-like C2-type 7Add
    BLAST
    Domaini2141 – 222989Ig-like C2-type 8Add
    BLAST
    Domaini2234 – 233198Ig-like C2-type 9Add
    BLAST
    Domaini2337 – 242791Ig-like C2-type 10Add
    BLAST
    Domaini2432 – 251887Ig-like C2-type 11Add
    BLAST
    Domaini2528 – 262396Ig-like C2-type 12Add
    BLAST

    Sequence similaritiesi

    Contains 6 LRR (leucine-rich) repeats.Curated
    Contains 1 LRRCT domain.Curated
    Contains 1 LRRNT domain.Curated

    Keywords - Domaini

    Immunoglobulin domain, Leucine-rich repeat, Repeat, Signal

    Phylogenomic databases

    eggNOGiNOG239806.
    HOGENOMiHOG000113014.
    HOVERGENiHBG107995.
    InParanoidiQ6WRI0.
    OMAiLVKIQVI.
    OrthoDBiEOG7HHWR7.
    PhylomeDBiQ6WRI0.
    TreeFamiTF326318.

    Family and domain databases

    Gene3Di2.60.40.10. 12 hits.
    InterProiIPR000483. Cys-rich_flank_reg_C.
    IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003599. Ig_sub.
    IPR003598. Ig_sub2.
    IPR001611. Leu-rich_rpt.
    IPR003591. Leu-rich_rpt_typical-subtyp.
    IPR000372. LRR-contain_N.
    [Graphical view]
    PfamiPF07679. I-set. 12 hits.
    PF13855. LRR_8. 1 hit.
    [Graphical view]
    SMARTiSM00409. IG. 2 hits.
    SM00408. IGc2. 10 hits.
    SM00369. LRR_TYP. 2 hits.
    SM00082. LRRCT. 1 hit.
    SM00013. LRRNT. 1 hit.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 12 hits.
    [Graphical view]

    Sequences (3)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q6WRI0-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MKVKGRGITC LLVSFAVICL VATPGGKACP RRCACYMPTE VHCTFRYLTS     50
    IPDSIPPNVE RINLGYNSLV RLMETDFSGL TKLELLMLHS NGIHTIPDKT 100
    FSDLQALQVL KMSYNKVRKL QKDTFYGLRS LTRLHMDHNN IEFINPEVFY 150
    GLNFLRLVHL EGNQLTKLHP DTFVSLSYLQ IFKISFIKFL YLSDNFLTSL 200
    PQEMVSYMPD LDSLYLHGNP WTCDCHLKWL SDWIQEKPDV IKCKKDRSPS 250
    SAQQCPLCMN PRTSKGKPLA MVSAAAFQCA KPTIDSSLKS KSLTILEDSS 300
    SAFISPQGFM APFGSLTLNM TDQSGNEANM VCSIQKPSRT SPIAFTEEND 350
    YIVLNTSFST FLVCNIDYGH IQPVWQILAL YSDSPLILER SHLLSETPQL 400
    YYKYKQVAPK PEDIFTNIEA DLRADPSWLM QDQISLQLNR TATTFSTLQI 450
    QYSSDAQITL PRAEMRPVKH KWTMISRDNN TKLEHTVLVG GTVGLNCPGQ 500
    GDPTPHVDWL LADGSKVRAP YVSEDGRILI DKSGKLELQM ADSFDTGVYH 550
    CISSNYDDAD ILTYRITVVE PLVEAYQENG IHHTVFIGET LDLPCHSTGI 600
    PDASISWVIP GNNVLYQSSR DKKVLNNGTL RILQVTPKDQ GYYRCVAANP 650
    SGVDFLIFQV SVKMKGQRPL EHDGETEGSG LDESNPIAHL KEPPGAQLRT 700
    SALMEAEVGK HTSSTSKRHN YRELTLQRRG DSTHRRFREN RRHFPPSARR 750
    IDPQHWAALL EKAKKNAMPD KRENTTVSPP PVVTQLPNIP GEEDDSSGML 800
    ALHEEFMVPA TKALNLPART VTADSRTISD SPMTNINYGT EFSPVVNSQI 850
    LPPEEPTDFK LSTAIKTTAM SKNINPTMSS QIQGTTNQHS STVFPLLLGA 900
    TEFQDSDQMG RGREHFQSRP PITVRTMIKD VNVKMLSSTT NKLLLESVNT 950
    TNSHQTSVRE VSEPRHNHFY SHTTQILSTS TFPSDPHTAA HSQFPIPRNS 1000
    TVNIPLFRRF GRQRKIGGRG RIISPYRTPV LRRHRYSIFR STTRGSSEKS 1050
    TTAFSATVLN VTCLSCLPRE RLTTATAALS FPSAAPITFP KADIARVPSE 1100
    ESTTLVQNPL LLLENKPSVE KTTPTIKYFR TEISQVTPTG AVMTYAPTSI 1150
    PMEKTHKVNA SYPRVSSTNE AKRDSVITSS LSGAITKPPM TIIAITRFSR 1200
    RKIPWQQNFV NNHNPKGRLR NQHKVSLQKS TAVMLPKTSP ALPRDKVSPF 1250
    HFTTLSTSVM QIPSNTLTTA HHTTTKTHNP GSLPTKKELP FPPLNPMLPS 1300
    IISKDSSTKS IISTQTAIPA TTPTFPASVI TYETQTERSR AQTIQREQEP 1350
    QKKNRTDPNI SPDQSSGFTT PTAMTPPVLT TAETSVKPSV SAFTHSPPEN 1400
    TTGISSTISF HSRTLNLTDV IEELAQASTQ TLKSTIASET TLSSKSHQST 1450
    TTRKAIIRHS TIPPFLSSSA TLMPVPISPP FTQRAVTDNV ATPISGLMTN 1500
    TVVKLHESSR HNAKPQQLVA EVATSPKVHP NAKFTIGTTH FIYSNLLHST 1550
    PMPALTTVKS QNSKLTPSPW AENQFWHKPY SEIAEKGKKP EVSMLATTGL 1600
    SEATTLVSDW DGQKNTKKSD FDKKPVQEAT TSKLLPFDSL SRYIFEKPRI 1650
    VGGKAASFTI PANSDAFLPC EAVGNPLPTI HWTRVPSGLD LSKRKQNSRV 1700
    QVLPNGTLSI QRVEIQDRGQ YLCSASNLFG TDHLHVTLSV VSYPPRILER 1750
    RTKEITVHSG STVELKCRAE GRPSPTVTWI LANQTVVSES SQGSRQAVVT 1800
    VDGTLVLHNL SIYDRGFYKC VASNPGGQDS LLVKIQVIAA PPVILEQRRQ 1850
    VIVGTWGESL KLPCTAKGTP QPSVYWVLSD GTEVKPLQFT NSKLFLFSNG 1900
    TLYIRNLASS DRGTYECIAT SSTGSERRVV MLTMEERVTS PRIEAASQKR 1950
    TEVNFGDKLL LNCSATGEPK PQIMWRLPSK AVVDQQHRVG SWIHVYPNGS 2000
    LFIGSVTEKD SGVYLCVARN KMGDDLILMH VSLRLKPAKI DHKQYFRKQV 2050
    LHGKDFQVDC KASGSPVPEI SWSLPDGTMI NNAMQADDSG HRTRRYTLFN 2100
    NGTLYFNKVG VAEEGDYTCY AQNTLGKDEM KVHLTVITAA PRIRQSNKTN 2150
    KRIKAGDTAV LDCEVTGDPK PKIFWLLPSN DMISFSIDRY TFHANGSLTI 2200
    NKVKLLDSGE YVCVARNPSG DDTKMYKLDV VSKPPLINGL YTNRTVIKAT 2250
    AVRHSKKHFD CRAEGTPSPE VMWIMPDNIF LTAPYYGSRI TVHKNGTLEI 2300
    RNVRLSDSAD FICVARNEGG ESVLVVQLEV LEMLRRPTFR NPFNEKIVAQ 2350
    LGKSTALNCS VDGNPPPEII WILPNGTRFS NGPQSYQYLI ASNGSFIISK 2400
    TTREDAGKYR CAARNKVGYI EKLVILEIGQ KPVILTYAPG TVKGISGESL 2450
    SLHCVSDGIP KPNIKWTMPS GYVVDRPQIN GKYILHDNGT LVIKEATAYD 2500
    RGNYICKAQN SVGHTLITVP VMIVAYPPRI TNRPPRSIVT RTGAAFQLHC 2550
    VALGVPKPEI TWEMPDHSLL STASKERTHG SEQLHLQGTL VIQNPQTSDS 2600
    GIYKCTAKNP LGSDYAATYI QVI 2623
    Length:2,623
    Mass (Da):290,838
    Last modified:July 5, 2004 - v1
    Checksum:iCBE7139B0DF16CF8
    GO
    Isoform 2 (identifier: Q6WRI0-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-1973: Missing.
         1974-1987: MWRLPSKAVVDQQH → MVESVRLENQPCDL

    Note: No experimental confirmation available.

    Show »
    Length:650
    Mass (Da):72,091
    Checksum:i8DA678726D7AF644
    GO
    Isoform 3 (identifier: Q6WRI0-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-2021: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:602
    Mass (Da):66,741
    Checksum:i6BA060C56FBE460B
    GO

    Sequence cautioni

    The sequence BAC05429.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti2243 – 22431N → S in AAH31063. (PubMed:15489334)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti124 – 1241T → I.
    Corresponds to variant rs35953658 [ dbSNP | Ensembl ].
    VAR_032179
    Natural varianti150 – 1501Y → D.
    Corresponds to variant rs7619322 [ dbSNP | Ensembl ].
    VAR_032180
    Natural varianti571 – 5711P → S.
    Corresponds to variant rs17204557 [ dbSNP | Ensembl ].
    VAR_032181
    Natural varianti795 – 7951D → N.
    Corresponds to variant rs58583961 [ dbSNP | Ensembl ].
    VAR_061313
    Natural varianti1199 – 11991S → A.
    Corresponds to variant rs16863403 [ dbSNP | Ensembl ].
    VAR_032182
    Natural varianti1370 – 13701T → I.
    Corresponds to variant rs34933248 [ dbSNP | Ensembl ].
    VAR_032183
    Natural varianti1875 – 18751Y → H.
    Corresponds to variant rs12487205 [ dbSNP | Ensembl ].
    VAR_032184
    Natural varianti2476 – 24761R → W.
    Corresponds to variant rs3732775 [ dbSNP | Ensembl ].
    VAR_032185
    Natural varianti2579 – 25791H → Y.
    Corresponds to variant rs7624011 [ dbSNP | Ensembl ].
    VAR_032186

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 20212021Missing in isoform 3. 1 PublicationVSP_025194Add
    BLAST
    Alternative sequencei1 – 19731973Missing in isoform 2. 1 PublicationVSP_025195Add
    BLAST
    Alternative sequencei1974 – 198714MWRLP…VDQQH → MVESVRLENQPCDL in isoform 2. 1 PublicationVSP_025196Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY273815 mRNA. Translation: AAQ16156.1.
    AK093069 mRNA. Translation: BAC04042.1.
    AK098838 mRNA. Translation: BAC05429.1. Different initiation.
    BC031063 mRNA. Translation: AAH31063.1.
    CCDSiCCDS3160.1. [Q6WRI0-1]
    RefSeqiNP_001171616.1. NM_001178145.1. [Q6WRI0-2]
    NP_001171617.1. NM_001178146.1. [Q6WRI0-3]
    NP_849144.2. NM_178822.4. [Q6WRI0-1]
    XP_005247434.1. XM_005247377.2. [Q6WRI0-1]
    XP_006713660.1. XM_006713597.1. [Q6WRI0-1]
    XP_006713663.1. XM_006713600.1. [Q6WRI0-3]
    UniGeneiHs.58561.

    Genome annotation databases

    EnsembliENST00000282466; ENSP00000282466; ENSG00000152580. [Q6WRI0-1]
    GeneIDi285313.
    KEGGihsa:285313.
    UCSCiuc011bob.2. human. [Q6WRI0-2]
    uc011boc.2. human. [Q6WRI0-3]
    uc011bod.2. human. [Q6WRI0-1]

    Polymorphism databases

    DMDMi74749492.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY273815 mRNA. Translation: AAQ16156.1 .
    AK093069 mRNA. Translation: BAC04042.1 .
    AK098838 mRNA. Translation: BAC05429.1 . Different initiation.
    BC031063 mRNA. Translation: AAH31063.1 .
    CCDSi CCDS3160.1. [Q6WRI0-1 ]
    RefSeqi NP_001171616.1. NM_001178145.1. [Q6WRI0-2 ]
    NP_001171617.1. NM_001178146.1. [Q6WRI0-3 ]
    NP_849144.2. NM_178822.4. [Q6WRI0-1 ]
    XP_005247434.1. XM_005247377.2. [Q6WRI0-1 ]
    XP_006713660.1. XM_006713597.1. [Q6WRI0-1 ]
    XP_006713663.1. XM_006713600.1. [Q6WRI0-3 ]
    UniGenei Hs.58561.

    3D structure databases

    ProteinModelPortali Q6WRI0.
    SMRi Q6WRI0. Positions 28-321, 490-651, 1629-2623.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 130074. 1 interaction.
    STRINGi 9606.ENSP00000282466.

    PTM databases

    PhosphoSitei Q6WRI0.

    Polymorphism databases

    DMDMi 74749492.

    Proteomic databases

    PaxDbi Q6WRI0.
    PRIDEi Q6WRI0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000282466 ; ENSP00000282466 ; ENSG00000152580 . [Q6WRI0-1 ]
    GeneIDi 285313.
    KEGGi hsa:285313.
    UCSCi uc011bob.2. human. [Q6WRI0-2 ]
    uc011boc.2. human. [Q6WRI0-3 ]
    uc011bod.2. human. [Q6WRI0-1 ]

    Organism-specific databases

    CTDi 285313.
    GeneCardsi GC03M151143.
    HGNCi HGNC:26384. IGSF10.
    HPAi HPA012921.
    neXtProti NX_Q6WRI0.
    PharmGKBi PA134900760.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG239806.
    HOGENOMi HOG000113014.
    HOVERGENi HBG107995.
    InParanoidi Q6WRI0.
    OMAi LVKIQVI.
    OrthoDBi EOG7HHWR7.
    PhylomeDBi Q6WRI0.
    TreeFami TF326318.

    Miscellaneous databases

    GenomeRNAii 285313.
    NextBioi 95425.
    PROi Q6WRI0.

    Gene expression databases

    ArrayExpressi Q6WRI0.
    Bgeei Q6WRI0.
    CleanExi HS_IGSF10.
    Genevestigatori Q6WRI0.

    Family and domain databases

    Gene3Di 2.60.40.10. 12 hits.
    InterProi IPR000483. Cys-rich_flank_reg_C.
    IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003599. Ig_sub.
    IPR003598. Ig_sub2.
    IPR001611. Leu-rich_rpt.
    IPR003591. Leu-rich_rpt_typical-subtyp.
    IPR000372. LRR-contain_N.
    [Graphical view ]
    Pfami PF07679. I-set. 12 hits.
    PF13855. LRR_8. 1 hit.
    [Graphical view ]
    SMARTi SM00409. IG. 2 hits.
    SM00408. IGc2. 10 hits.
    SM00369. LRR_TYP. 2 hits.
    SM00082. LRRCT. 1 hit.
    SM00013. LRRNT. 1 hit.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 12 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "CMF608 -- a novel mechanical strain-induced bone-specific protein expressed in early osteochondroprogenitor cells."
      Segev O., Samach A., Faerman A., Kalinski H., Beiman M., Gelfand A., Turam H., Boguslavsky S., Moshayov A., Gottlieb H., Kazanov E., Nevo Z., Robinson D., Skaliter R., Einat P., Binderman I., Feinstein E.
      Bone 34:246-260(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2187-2623 (ISOFORM 1).
      Tissue: Testis.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
      Tissue: Testis.

    Entry informationi

    Entry nameiIGS10_HUMAN
    AccessioniPrimary (citable) accession number: Q6WRI0
    Secondary accession number(s): Q86YJ9, Q8N772, Q8NA84
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 15, 2007
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3