Q6WNX8 (Q6WNX8_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
G-protein coupled receptor EMBL AAQ19543.1

Gene names

ORF Names:

CG8784 FlyBase FBgn0038140

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	658 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane RuleBase RU000688
Molecular function	G-protein coupled receptor RuleBase RU000688 Receptor Transducer
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	neuropeptide receptor activity Inferred from direct assay Ref.1. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6WNX8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: D0AC482A3E5560F7	FASTA	658	72,176
	10 20 30 40 50 60 MLQGVAITIA NDSNDDGLNQ SFMAHVSPSP NQSPSIGVGI GIASSTMANP SESPEMLLLK 70 80 90 100 110 120 NDKFLTHVAH LLNITTENLS NLLGSTNGTN ASTMAADSPV DESLTLRTAL TVCYALIFVA 130 140 150 160 170 180 GVLGNLITCI VISRNNFMHT ATNFYLFNLA VSDLILLVSG IPQELYNLWY PDMYPFTDAM 190 200 210 220 230 240 CIMGSVLSEM AANATVLTIT AFTVERYIAI CHPFRQHTMS KLSRAIKFIF AIWLAAFLLA 250 260 270 280 290 300 LPQAMQFSVV YQNEGYSCTM ENDFYAHVFA VSGFIFFGGP MTAICVLYVL IGVKLKRSRL 310 320 330 340 350 360 LQSLPRRTFD ANRGLNAQGR VIRMLVAVAV AFFLCWAPFH AQRLMAVYGL NLINIGISRD 370 380 390 400 410 420 AFNDYFRILD YTSGVLYFLS TCINPLLYNI MSHKFREAFK ITLTRQFGLA RNHHHQQSQH 430 440 450 460 470 480 HQHNYSALLR QNGSMRLQPA SCSVNNNALE PYGSYRVVQF RCRDANHQLS LQDSIRTTTT 490 500 510 520 530 540 TTTINSNSMA AGNGVGGGAG GGGRRLRKQE LYGPVPGTAV PHRMLQAQVS QLSSLGDANS 550 560 570 580 590 600 LLEAEVVDRH YASGRAKRAL LATKSGALLV TPPQSGDPSE VSQPATRLKL TRVISRRDEV 610 620 630 640 650 ANASTPPFCG SHSLPDPETC QSASVAGRSS RKFPWRKRRQ KTEDPSSEGL TYGSPKSQ

References

[1]	"Molecular cloning, functional expression, and gene silencing of two Drosophila receptors for the Drosophila neuropeptide pyrokinin-2." Rosenkilde C., Cazzamali G., Williamson M., Hauser F., Sondergaard L., DeLotto R., Grimmelikhuijzen C.J. Biochem. Biophys. Res. Commun. 309:485-494(2003) [PubMed: 12951076] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Rosenkilde C.H., Cazzamali G., Williamson M.R., Grimmelikhuijzen C.J.P. Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY277898 mRNA. Translation: AAQ19543.1.
3D structure databases
ProteinModelPortal	Q6WNX8.
SMR	Q6WNX8. Positions 107-404.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6WNX8.
Protein family/group databases
GPCRDB	Search...
Proteomic databases
PRIDE	Q6WNX8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0038140. CG8784.
Phylogenomic databases
eggNOG	inNOG08881.
InParanoid	Q6WNX8.
OrthoDB	EOG4DZ09J.
Gene expression databases
ArrayExpress	Q6WNX8.
Bgee	Q6WNX8.
Family and domain databases
InterPro	IPR000276. 7TM_GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_supfam. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6WNX8_DROME

Accession

Primary (citable) accession number: Q6WNX8

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	November 16, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)