Unreviewed, UniProtKB/TrEMBL Q6WDF7 (Q6WDF7_RAT)

Names and origin

Protein names

Submitted name:
    C-myc EMBL AAQ57167.1

Gene names

Name:	Myc RGD 3130
Synonyms:	c-myc EMBL AAQ57167.1

Organism

Rattus norvegicus (Rat) EMBL AAQ57167.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	187 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 basic helix-loop-helix (bHLH) domain. Spearmint SPM011598 RuleBase RU000367V1

Ontologies

Keywords
Cellular component	Nucleus Spearmint SPM012682
Gene Ontology (GO)
Biological process	B cell apoptosis Inferred from electronic annotation. Source: Compara DNA fragmentation involved in apoptosis Inferred from electronic annotation. Source: Compara activation of caspase activity Inferred from electronic annotation. Source: Compara activation of pro-apoptotic gene products Inferred from electronic annotation. Source: Compara detection of mechanical stimulus involved in sensory perception of sound Inferred from electronic annotation. Source: Compara glucose metabolic process Inferred from mutant phenotype. Source: RGD induction of apoptosis by intracellular signals Inferred from electronic annotation. Source: Compara middle ear morphogenesis Inferred from electronic annotation. Source: Compara negative regulation of survival gene product expression Inferred from electronic annotation. Source: Compara pathogenesis Traceable author statement. Source: RGD pigmentation Inferred from electronic annotation. Source: Compara positive regulation of B cell apoptosis Inferred from electronic annotation. Source: Compara positive regulation of cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from mutant phenotype. Source: RGD protein processing Inferred from electronic annotation. Source: Compara regulation of mitotic cell cycle Inferred from mutant phenotype. Source: RGD release of cytochrome c from mitochondria Inferred from electronic annotation. Source: Compara response to alkaloid Inferred from electronic annotation. Source: Compara response to radiation Inferred from electronic annotation. Source: Compara skeletal system morphogenesis Inferred from electronic annotation. Source: Compara transcription from RNA polymerase II promoter Inferred from direct assay. Source: RGD transcription initiation Inferred from direct assay. Source: RGD
Cellular component	cytoplasm Inferred from direct assay. Source: RGD nuclear body Inferred from electronic annotation. Source: Compara nucleolus Inferred from direct assay. Source: RGD spindle Inferred from electronic annotation. Source: Compara
Molecular function	double-stranded DNA binding Inferred from direct assay. Source: RGD protein heterodimerization activity Inferred from physical interaction. Source: RGD sequence-specific DNA binding Inferred from direct assay. Source: RGD transcription factor activity Inferred from direct assay. Source: RGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAQ57167.1

Sequences

	Sequence		Length	Mass (Da)
	Q6WDF7-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 416F29FFD7D99917	FASTA	187	21,551
	10 20 30 40 50 60 EEEQDDEEEI DVVSVEKRQP PAKRSESGSS PSRGHSKPPH SPLVLKRCHV STHQHNYAAP 70 80 90 100 110 120 PSTRKDYPAA KRAKLDSGRV LKQISNNRKC SSPRSSDTEE NDKRRTHNVL ERQRRNELKR 130 140 150 160 170 180 SFFALRDQIP ELENNEKAPK VVILKKATAY ILSVQADEHK LISEKDLLRK RREQLKHKLE QLRNSGA

References

[1]	"Phylogeny and divergence-date estimates of rapid radiations in muroid rodents based on multiple nuclear genes." Steppan S., Adkins R., Anderson J. Syst. Biol. 53:533-553(2004) [PubMed: 15371245] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Sprague-Dawley EMBL AAQ57167.1.
[2]	Steppan S.J., Adkins R.M., Anderson J. Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Sprague-Dawley EMBL AAQ57167.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY294970 Genomic DNA. Translation: AAQ57167.1.
IPI	IPI00214655.
UniGene	Rn.12072
3D structure databases
HSSP	HSSP built from PDB template 1A93 based on UniProtKB P01106.
SMR	Q6WDF7. Positions 101-182.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6WDF7.
Genome annotation databases
Ensembl	ENSRNOT00000006188; ENSRNOP00000006188; ENSRNOG00000004500; Rattus norvegicus. [Genome view]
Phylogenomic databases
HOVERGEN	Q6WDF7.
Gene expression databases
ArrayExpress	Q6WDF7.
Genevestigator	Q6WDF7.
Family and domain databases
InterPro	IPR001092. HLH_basic. IPR011598. HLH_DNA_bd. IPR003327. Myc-LZ. IPR002418. Tscrpt_reg_Myc. IPR012682. Tscrpt_reg_Myc_N. [Graphical view]
Gene3D	G3DSA:4.10.280.10. HLH_DNA_bd. 1 hit.
Pfam	PF00010. HLH. 1 hit. PF02344. Myc-LZ. 1 hit. PF01056. Myc_N. 1 hit. [Graphical view]
PRINTS	PR00044. LEUZIPPRMYC.
SMART	SM00353. HLH. 1 hit. [Graphical view]
PROSITE	PS50888. HLH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6WDF7_RAT

Accession

Primary (citable) accession number: Q6WDF7

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	November 3, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)