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Q6WDF1

- Q6WDF1_MOUSE

UniProt

Q6WDF1 - Q6WDF1_MOUSE

Protein
Submitted name:

C-myc

Gene

c-myc

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. double-stranded DNA binding Source: Ensembl
    2. sequence-specific DNA binding Source: Ensembl
    3. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. amino acid transport Source: Ensembl
    2. canonical Wnt signaling pathway involved in positive regulation of wound healing Source: Ensembl
    3. cell proliferation Source: Ensembl
    4. cellular response to carbohydrate stimulus Source: Ensembl
    5. cellular response to estrogen stimulus Source: Ensembl
    6. cellular response to hydrostatic pressure Source: Ensembl
    7. cellular response to interleukin-1 Source: Ensembl
    8. DNA-templated transcription, initiation Source: Ensembl
    9. embryo development Source: Ensembl
    10. flavonoid metabolic process Source: Ensembl
    11. fungal-type cell wall polysaccharide metabolic process Source: Ensembl
    12. G0 to G1 transition Source: Ensembl
    13. glucose metabolic process Source: Ensembl
    14. glycoprotein metabolic process Source: Ensembl
    15. hypothalamus development Source: Ensembl
    16. inner mitochondrial membrane organization Source: Ensembl
    17. lactic acid secretion Source: Ensembl
    18. negative regulation of cell death Source: Ensembl
    19. negative regulation of glucose import Source: Ensembl
    20. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
    21. positive regulation of ATP biosynthetic process Source: Ensembl
    22. positive regulation of cell cycle Source: Ensembl
    23. positive regulation of cell proliferation Source: Ensembl
    24. positive regulation of cellular respiration Source: Ensembl
    25. positive regulation of glycolytic process Source: Ensembl
    26. positive regulation of mitochondrial membrane potential Source: Ensembl
    27. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    28. pyruvate transport Source: Ensembl
    29. regulation of mitotic cell cycle Source: Ensembl
    30. regulation of oxidative phosphorylation Source: Ensembl
    31. response to estradiol Source: Ensembl
    32. response to wounding Source: Ensembl
    33. transcription from RNA polymerase II promoter Source: Ensembl
    34. transformation of host cell by virus Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    C-mycImported
    Gene namesi
    Name:c-mycImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrion Source: GOC
    2. nucleus Source: InterPro

    Expressioni

    Gene expression databases

    ArrayExpressiQ6WDF1.
    BgeeiQ6WDF1.
    GenevestigatoriQ6WDF1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6WDF1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 basic helix-loop-helix (bHLH) domain.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000043075.
    HOVERGENiHBG000472.
    InParanoidiQ6WDF1.

    Family and domain databases

    Gene3Di4.10.280.10. 1 hit.
    InterProiIPR011598. bHLH_dom.
    IPR003327. Myc-LZ.
    IPR002418. Tscrpt_reg_Myc.
    IPR012682. Tscrpt_reg_Myc_N.
    [Graphical view]
    PfamiPF00010. HLH. 1 hit.
    PF02344. Myc-LZ. 1 hit.
    PF01056. Myc_N. 1 hit.
    [Graphical view]
    PRINTSiPR00044. LEUZIPPRMYC.
    SMARTiSM00353. HLH. 1 hit.
    [Graphical view]
    SUPFAMiSSF47459. SSF47459. 1 hit.
    PROSITEiPS50888. BHLH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q6WDF1-1 [UniParc]FASTAAdd to Basket

    « Hide

    EEEQEDEEEI DVVSVEKRQT PAKRSESGSS PSRGHSKPPH SPLVLKRCHV    50
    STHQHNYAAP PSTRKDYPAA KRAKLDSGRV LKQISNNRKC SSPRSSDTEE 100
    NDKRRTHNVL ERQRRNELKR SFFALRDQIP ELENNEKAPK VVILKKATAY 150
    ILSIQADEHK LTSEKDLLRK RREQLKHKLE QLRNSGA 187
    Length:187
    Mass (Da):21,571
    Last modified:July 5, 2004 - v1
    Checksum:i1E6D506C13DDDCC6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY294976 Genomic DNA. Translation: AAQ57173.1.
    UniGeneiMm.2444.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY294976 Genomic DNA. Translation: AAQ57173.1 .
    UniGenei Mm.2444.

    3D structure databases

    ProteinModelPortali Q6WDF1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000043075.
    HOVERGENi HBG000472.
    InParanoidi Q6WDF1.

    Miscellaneous databases

    ChiTaRSi MYC. mouse.

    Gene expression databases

    ArrayExpressi Q6WDF1.
    Bgeei Q6WDF1.
    Genevestigatori Q6WDF1.

    Family and domain databases

    Gene3Di 4.10.280.10. 1 hit.
    InterProi IPR011598. bHLH_dom.
    IPR003327. Myc-LZ.
    IPR002418. Tscrpt_reg_Myc.
    IPR012682. Tscrpt_reg_Myc_N.
    [Graphical view ]
    Pfami PF00010. HLH. 1 hit.
    PF02344. Myc-LZ. 1 hit.
    PF01056. Myc_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00044. LEUZIPPRMYC.
    SMARTi SM00353. HLH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47459. SSF47459. 1 hit.
    PROSITEi PS50888. BHLH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Steppan S.J., Adkins R.M., Anderson J.
      Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/cImported.
    2. "Phylogeny and divergence-date estimates of rapid radiations in muroid rodents based on multiple nuclear genes."
      Steppan S., Adkins R., Anderson J.
      Syst. Biol. 53:533-553(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/cImported.

    Entry informationi

    Entry nameiQ6WDF1_MOUSE
    AccessioniPrimary (citable) accession number: Q6WDF1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)