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Q6WDF1

- Q6WDF1_MOUSE

UniProt

Q6WDF1 - Q6WDF1_MOUSE

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Protein
Submitted name:

C-myc

Gene

c-myc

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. double-stranded DNA binding Source: Ensembl
  2. sequence-specific DNA binding Source: Ensembl
  3. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. amino acid transport Source: Ensembl
  2. canonical Wnt signaling pathway involved in positive regulation of wound healing Source: Ensembl
  3. cell proliferation Source: Ensembl
  4. cellular response to carbohydrate stimulus Source: Ensembl
  5. cellular response to estrogen stimulus Source: Ensembl
  6. cellular response to hydrostatic pressure Source: Ensembl
  7. cellular response to interleukin-1 Source: Ensembl
  8. DNA-templated transcription, initiation Source: Ensembl
  9. flavonoid metabolic process Source: Ensembl
  10. fungal-type cell wall polysaccharide metabolic process Source: Ensembl
  11. G0 to G1 transition Source: Ensembl
  12. glucose metabolic process Source: Ensembl
  13. glycoprotein metabolic process Source: Ensembl
  14. hypothalamus development Source: Ensembl
  15. inner mitochondrial membrane organization Source: Ensembl
  16. in utero embryonic development Source: Ensembl
  17. lactic acid secretion Source: Ensembl
  18. negative regulation of cell death Source: Ensembl
  19. negative regulation of glucose import Source: Ensembl
  20. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
  21. positive regulation of ATP biosynthetic process Source: Ensembl
  22. positive regulation of cell cycle Source: Ensembl
  23. positive regulation of cell proliferation Source: Ensembl
  24. positive regulation of cellular respiration Source: Ensembl
  25. positive regulation of glycolytic process Source: Ensembl
  26. positive regulation of mitochondrial membrane potential Source: Ensembl
  27. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  28. pyruvate transport Source: Ensembl
  29. regulation of mitotic cell cycle Source: Ensembl
  30. regulation of oxidative phosphorylation Source: Ensembl
  31. response to estradiol Source: Ensembl
  32. response to wounding Source: Ensembl
  33. transcription from RNA polymerase II promoter Source: Ensembl
  34. transformation of host cell by virus Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
C-mycImported
Gene namesi
Name:c-mycImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: Ensembl
  2. nucleus Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ6WDF1.
ExpressionAtlasiQ6WDF1. baseline and differential.
GenevestigatoriQ6WDF1.

Structurei

3D structure databases

ProteinModelPortaliQ6WDF1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 basic helix-loop-helix (bHLH) domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000043075.
HOVERGENiHBG000472.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
IPR003327. Myc-LZ.
IPR002418. Tscrpt_reg_Myc.
IPR012682. Tscrpt_reg_Myc_N.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
PF02344. Myc-LZ. 1 hit.
PF01056. Myc_N. 1 hit.
[Graphical view]
PRINTSiPR00044. LEUZIPPRMYC.
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6WDF1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
EEEQEDEEEI DVVSVEKRQT PAKRSESGSS PSRGHSKPPH SPLVLKRCHV
60 70 80 90 100
STHQHNYAAP PSTRKDYPAA KRAKLDSGRV LKQISNNRKC SSPRSSDTEE
110 120 130 140 150
NDKRRTHNVL ERQRRNELKR SFFALRDQIP ELENNEKAPK VVILKKATAY
160 170 180
ILSIQADEHK LTSEKDLLRK RREQLKHKLE QLRNSGA
Length:187
Mass (Da):21,571
Last modified:July 5, 2004 - v1
Checksum:i1E6D506C13DDDCC6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY294976 Genomic DNA. Translation: AAQ57173.1.
UniGeneiMm.2444.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY294976 Genomic DNA. Translation: AAQ57173.1 .
UniGenei Mm.2444.

3D structure databases

ProteinModelPortali Q6WDF1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOGENOMi HOG000043075.
HOVERGENi HBG000472.

Miscellaneous databases

ChiTaRSi Myc. mouse.

Gene expression databases

Bgeei Q6WDF1.
ExpressionAtlasi Q6WDF1. baseline and differential.
Genevestigatori Q6WDF1.

Family and domain databases

Gene3Di 4.10.280.10. 1 hit.
InterProi IPR011598. bHLH_dom.
IPR003327. Myc-LZ.
IPR002418. Tscrpt_reg_Myc.
IPR012682. Tscrpt_reg_Myc_N.
[Graphical view ]
Pfami PF00010. HLH. 1 hit.
PF02344. Myc-LZ. 1 hit.
PF01056. Myc_N. 1 hit.
[Graphical view ]
PRINTSi PR00044. LEUZIPPRMYC.
SMARTi SM00353. HLH. 1 hit.
[Graphical view ]
SUPFAMi SSF47459. SSF47459. 1 hit.
PROSITEi PS50888. BHLH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Steppan S.J., Adkins R.M., Anderson J.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
  2. "Phylogeny and divergence-date estimates of rapid radiations in muroid rodents based on multiple nuclear genes."
    Steppan S., Adkins R., Anderson J.
    Syst. Biol. 53:533-553(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.

Entry informationi

Entry nameiQ6WDF1_MOUSE
AccessioniPrimary (citable) accession number: Q6WDF1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 26, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)