Q6W5P8 (Q6W5P8_9ACTO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
FscF EMBL AAQ82566.1

Gene names

Name:

fscF EMBL AAQ82566.1

Organism

Streptomyces sp. FR-008 EMBL AAQ82566.1

Taxonomic identifier

206662 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	2049 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Phosphopantetheine RuleBase RU000721
Molecular function	Transferase RuleBase RU000693
Gene Ontology (GO)
Biological process	biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro hydrolase activity, acting on ester bonds Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6W5P8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 993B5EB7BDF0C0C3	FASTA	2,049	213,663
	10 20 30 40 50 60 MPDDKKLVDY LKWVTADLHK TRRRLEEAEA HRREPIAVVG MACRLPGGVA TPEEYWRLLE 70 80 90 100 110 120 EGRDGIAPFP ADRGWDLDAL NGEGAGSSAA GEGGFVDAAA FDAGFFGISP REAVAMDPQQ 130 140 150 160 170 180 RILLETTWEA VERAGIDPVS LRGSRTGVYV GTAGVDYVGV VMNSREDAEG HATTGLTASV 190 200 210 220 230 240 VSGRLSYAFD LAGPAVTVDT ACSASLVAIH LAAQALRNGE CGLALAGGVT VMSTPMGFSG 250 260 270 280 290 300 FTRQGGISTS GRCKAFADSA DGTGWAEGAG VLVLERLSDA RRNGHQVLAV VRGSAVNQDG 310 320 330 340 350 360 ASNGLTAPNG PSQQRVIRQA LAGAGLSAAD VDAVEAHGTG TPLGDPIEAQ ALLATYGQDR 370 380 390 400 410 420 PEDRPLLLGS VKSNIGHSQA AAGVAGVIKT VLAIQHGVLP RSLHIDEASS HVDWGAGNVR 430 440 450 460 470 480 LLTENTAWPE TGRPRRAGVS SFGISGTNAH VVIEQAPEPE EPATPEDGTP TARPTLVPWP 490 500 510 520 530 540 VSAKTREALD AQLARVTSVT GAAPLDIGHS LATGRSTFEH RAVLLAGPEG EPAEAARGRA 550 560 570 580 590 600 TERTLALLFS GQGSQRAGMG RELYERFPVF AEALDAVVAR LDTGLERSLR EVLFVEEGSE 610 620 630 640 650 660 AAALLDVTGY TQPALFAVEV ALFRLVESWG VSPEFVAGHS VGEIAAAHVA GVFSLDDACR 670 680 690 700 710 720 LVAARARLMQ ELPTGGAMVA VRATEAEVTP RLTEGLSLAA VNGPDSVVVS GPEGEVTALA 730 740 750 760 770 780 AEFETEGRKI QRLSVSHAFH SALMEPMLDA FREVARSLEY AEPRVPVVSN VTGALAAPGQ 790 800 810 820 830 840 LTDPEYWVRH VRETVRFADG VRTLAEAGAD AFLEIGPGGV LTALARQSLD TLDGGTGAVA 850 860 870 880 890 900 APALRSRRPE QEALLTGLAQ LHVAGVRVDW AAWFTGTGAR RTDLPTYAWQ HRRYWPRPLA 910 920 930 940 950 960 HAADIPGAGL TPAEHPLLGA AVSLAGSEGV LLTGRVGLRT HPWLADHVMG GLVLFPATAF 970 980 990 1000 1010 1020 LELAVRAGDQ AGCGRVQELT LTTPLALDPR GAASVQVGVG PPDAAGCRPL AIHSRPEDAA 1030 1040 1050 1060 1070 1080 DDEPWTQHAT GVLVAGARQV AFGQSAWPPA DATPVDLDGF YERTEYGPLF QGLRAVWTRG 1090 1100 1110 1120 1130 1140 DEVLAELELP ARADDAALFG LHPALLTAAL HAVEYVELKD ADQGLLPFSW SGVTLHASGA 1150 1160 1170 1180 1190 1200 ARLRVRITKA GEDTVSIAAV DTAGRPVLSV ESLALRPSGA ARLLKPGTDR STLLGLDWVP 1210 1220 1230 1240 1250 1260 AEPTGPAAGG PRVALGTDPF GTGTVLAGLD EVTETGTQVL VPVPDGGEDP VTATHEATRA 1270 1280 1290 1300 1310 1320 TLALLQEWLD GPRPAGARLV FVARGVVAAR PGDPAANLAG AAVWGMVRTA QAEHPADFTL 1330 1340 1350 1360 1370 1380 VDVEPGAPFP LEAVLAVDEP QAAVRDGQVL VGRLTQLPPP TPQDGPENTD PFGVTRDGTV 1390 1400 1410 1420 1430 1440 LVTGGTGTLG ARTARHLVTR HGVTRLLLAG RRGPDAPGAA ALREELTALG AHVTVAACDV 1450 1460 1470 1480 1490 1500 SDRDALAALL GGIPAEHPLT AVVHAAGVLD DAVVTSLTPD RLATVLRSKA DAAWHLHDLT 1510 1520 1530 1540 1550 1560 RGLGLDAFVL YSSISGVTAR AGQANYVAAN LFLDTLAQHR AAQGLPALSV AWGAWDLDEG 1570 1580 1590 1600 1610 1620 MAGDLLTDTG RRRIRSGGID TLPGDRALDL LDTALTLGEP LVVATNLAAP PATAHLDEVP 1630 1640 1650 1660 1670 1680 PLMRGLVRPP RRTAAATTDA PARVLDAASF RENFANLGAG EQETTLRETV VACAAALLGH 1690 1700 1710 1720 1730 1740 TDTSEIDPDR DFLELGFDSL IGIELRRKLS EITGLQLPAS IVYDSGSPNG LTAWLRTELG 1750 1760 1770 1780 1790 1800 AQGSGAPQTG AAGGPTENDS MERLFLDGLA QGKVREAQRM LATVAALRPS FEVTAELEDL 1810 1820 1830 1840 1850 1860 PWPVTLAEGP APTRLVCVSA PTANGGVHQY ATLSGHFRGR RDVTALPLIG FNTGEALPAH 1870 1880 1890 1900 1910 1920 AEAAARIIAD CTLQAADGKP FVLVGHSSGG SLAYAAAGVL EHTWGIRPEA VVLLDTLSIQ 1930 1940 1950 1960 1970 1980 HKSDEGVDYN GMMKFNFTAV DDSPVRLTNS RLSAMGRWMV LLNALDVHPT TVPVLEIKCT 1990 2000 2010 2020 2030 2040 RALIEGVPAP DPERLHLPVV PDAEVRPLDS DHLSLIREDS GPAADLMDAW LTALETTATT DAPETAPAG

References

[1]	"Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex." Chen S., Huang X., Zhou X., Bai L., He J., Jeong K.J., Lee S.Y., Deng Z. Chem. Biol. 10:1065-1076(2003) [PubMed: 14652074] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Chen S., Huang X., Zhou X., He J., Bai L., Jeong K.J., Lee S.Y., Deng Z. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY310323 Genomic DNA. Translation: AAQ82566.1.
3D structure databases
ProteinModelPortal	Q6W5P8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001227. Ac_transferase_dom. IPR009081. Acyl_carrier_prot-like. IPR014043. Acyl_transferase. IPR016035. Acyl_Trfase/lysoPLipase. IPR000794. Beta-ketoacyl_synthase. IPR018201. Ketoacyl_synth_AS. IPR014031. Ketoacyl_synth_C. IPR014030. Ketoacyl_synth_N. IPR016036. Malonyl_transacylase_ACP-bd. IPR016040. NAD(P)-bd_dom. IPR006163. Phsphopanteth-bd. IPR020842. PKS/FAS_KR. IPR020801. PKS_acyl_transferase. IPR020841. PKS_Beta-ketoAc_synthase_dom. IPR020807. PKS_dehydratase. IPR013968. PKS_KR. IPR020806. PKS_PP-bd. IPR020802. PKS_thioesterase. IPR015083. Polyketide_synth_docking. IPR006162. PPantetheine_attach_site. IPR001031. Thioesterase. IPR016039. Thiolase-like. IPR016038. Thiolase-like_subgr. [Graphical view]
Gene3D	G3DSA:3.40.366.10. Ac_transferase_reg. 2 hits. G3DSA:1.10.1200.10. ACP_like. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:3.40.47.10. Thiolase-like_subgr. 2 hits.
PANTHER	PTHR11712. Ketoacyl_synth. 1 hit.
Pfam	PF00698. Acyl_transf_1. 1 hit. PF08990. Docking. 1 hit. PF00109. ketoacyl-synt. 1 hit. PF02801. Ketoacyl-synt_C. 1 hit. PF08659. KR. 1 hit. PF00550. PP-binding. 1 hit. PF00975. Thioesterase. 1 hit. [Graphical view]
SMART	SM00827. PKS_AT. 1 hit. SM00826. PKS_DH. 1 hit. SM00822. PKS_KR. 1 hit. SM00825. PKS_KS. 1 hit. SM00823. PKS_PP. 1 hit. SM00824. PKS_TE. 1 hit. [Graphical view]
SUPFAM	SSF47336. ACP_like. 1 hit. SSF52151. Acyl_Trfase/lysoPlipase. 1 hit. SSF55048. Malonyl_transacylase_ACP-bd. 1 hit. SSF53901. Thiolase-like. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 1 hit. PS00606. B_KETOACYL_SYNTHASE. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6W5P8_9ACTO

Accession

Primary (citable) accession number: Q6W5P8

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)