Chemotaxis response regulator protein-glutamate methylesterase

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Q6W1R5 (Q6W1R5_RHISN) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 79. History...

Clusters with 100%, 90%, 50% identity |

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Recommended name:
Chemotaxis response regulator protein-glutamate methylesterase HAMAP-Rule MF_00099
EC=3.1.1.61 HAMAP-Rule MF_00099

Gene names

Name:	cheB1 EMBL ACP21840.1
Synonyms:	cheB HAMAP-Rule MF_00099
Ordered Locus Names:	NGR_b03760 EMBL ACP21840.1
ORF Names:	RNGR00529 EMBL AAQ87303.1

Encoded on

Plasmid pNGR234b EMBL ACP21840.1
Plasmid sym pNGR234b Ref.2 Ref.3
Plasmid megaplasmid 2 Ref.1 EMBL AAQ87303.1

Organism

Rhizobium sp. (strain NGR234) [Complete proteome] [HAMAP] EMBL AAQ87303.1

Taxonomic identifier

394 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium ›

Protein attributes

Sequence length	348 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR By similarity. SAAS SAAS000673 HAMAP-Rule MF_00099
Catalytic activity	Protein L-glutamate O(5)-methyl ester + H₂O = protein L-glutamate + methanol. SAAS SAAS000673 HAMAP-Rule MF_00099
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00099.
Domain	The N-terminal regulatory domain inhibits the activity of the C-terminal effector domain By similarity. HAMAP-Rule MF_00099
Sequence similarities	Contains 1 cheB-type methylesterase domain. SAAS SAAS000673 HAMAP-Rule MF_00099 Contains 1 response regulatory domain. SAAS SAAS000673 HAMAP-Rule MF_00099

Ontologies

Keywords
Biological process	Chemotaxis SAAS SAAS000673 HAMAP-Rule MF_00099
Cellular component	Cytoplasm SAAS SAAS000673 HAMAP-Rule MF_00099
Molecular function	Hydrolase SAAS SAAS000673 HAMAP-Rule MF_00099 EMBL AAQ87303.1
PTM	Phosphoprotein SAAS SAAS000673
Technical term	Complete proteome Plasmid EMBL AAQ87303.1
Gene Ontology (GO)
Biological_process	chemotaxis Inferred from electronic annotation. Source: HAMAP intracellular signal transduction Inferred from electronic annotation. Source: GOC regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro sensory perception of chemical stimulus Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	phosphorelay response regulator activity Inferred from electronic annotation. Source: InterPro protein-glutamate methylesterase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Domain

3 – 119

117

Response regulatory By similarity HAMAP-Rule MF_00099

Domain

157 – 344

188

CheB-type methylesterase By similarity HAMAP-Rule MF_00099

Sites

Active site

166

By similarity HAMAP-Rule MF_00099

Active site

193

By similarity HAMAP-Rule MF_00099

Active site

286

By similarity HAMAP-Rule MF_00099

Sequences

Sequence

Length

Mass (Da)

Tools

Q6W1R5 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: D8AD4A3ABE288734
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FASTA

348

36,186

        10         20         30         40         50         60 
MVRILLATSR VDLQELVERA VRSDASAELL GVARSFAEAV TMARQLSPDI VTMELRLGEH 

        70         80         90        100        110        120 
DSVEAVREIM VSAPAPIVMV SRVEELGSVA ARALDAGALA VIPAPPPVDG RLEKAATEKF 

       130        140        150        160        170        180 
LSTIKAMAHV KVVRQWRKKS GGDGRNDQGD LAAAHAPIGI VGIAASTGGP AAIRSILMNV 

       190        200        210        220        230        240 
SSKFPAPILI VQHMSSGFID RVAASLDATV PLNVKVATDG ERLRAGMVYL APDGRQLGVS 

       250        260        270        280        290        300 
GRSRIRVVND APVDGFKPSG SYLFGSIARA FKGEALAVIL TGMGNDGTEG LRALREAGGK 

       310        320        330        340 
AIAQDEESSV VFGMPKSAIG AGLVDFVLPL ESIGGKIVAL AEGRESGT

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative DNA analysis of two large contigs of the Rhizobium sp. NGR234 megaplasmid 2." Broughton W.J., Perret X., Staehelin C., Schmitz R.A., Raasch C., Liesegang H., Gottschalk G., Streit W.R. Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: NGR234 EMBL AAQ87303.1.
[2]	"An evolutionary hot spot: the pNGR234b replicon of Rhizobium sp. strain NGR234." Streit W.R., Schmitz R.A., Perret X., Staehelin C., Deakin W.J., Raasch C., Liesegang H., Broughton W.J. J. Bacteriol. 186:535-542(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NGR234.
[3]	"Rhizobium sp. strain NGR234 possesses a remarkable number of secretion systems." Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A., Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A., Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A., Broughton W.J., Perret X., Strittmatter A.W., Streit W.R. Appl. Environ. Microbiol. 75:4035-4045(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NGR234 EMBL ACP21840.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY316747 Genomic DNA. Translation: AAQ87303.1. CP000874 Genomic DNA. Translation: ACP21840.1.
RefSeq	YP_002822593.1. NC_012586.1.
3D structure databases
HSSP	HSSP built from PDB template 1A2O based on UniProtKB P04042.
ModBase	Search...
Protein-protein interaction databases
STRING	394.NGR_b03760.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACP21840; ACP21840; NGR_b03760.
GeneID	7789912.
KEGG	rhi:NGR_b03760.
PATRIC	32302376. VBIRhiSp122450_0823.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2201.
HOGENOM	HOG000151424.
KO	K03412.
OMA	MPKSAIG.
ProtClustDB	CLSK807707.
Family and domain databases
Gene3D	3.40.50.180. 1 hit.
HAMAP	MF_00099. CheB_methylest.
InterPro	IPR011006. CheY-like_superfamily. IPR008248. Sig_transdc_resp-reg_CheB. IPR000673. Sig_transdc_resp-reg_Me-estase. IPR001789. Sig_transdc_resp-reg_receiver. [Graphical view]
Pfam	PF01339. CheB_methylest. 1 hit. PF00072. Response_reg. 1 hit. [Graphical view]
PIRSF	PIRSF000876. RR_chemtxs_CheB. 1 hit.
SMART	SM00448. REC. 1 hit. [Graphical view]
SUPFAM	SSF52738. Chemotax_RR_pGlu_Me-esterase. 1 hit. SSF52172. CheY_like. 1 hit.
PROSITE	PS50122. CHEB. 1 hit. PS50110. RESPONSE_REGULATORY. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6W1R5_RHISN

Accession

Primary (citable) accession number: Q6W1R5

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Regions

Sites

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry information