Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q6VZL8 (PAP1_CNPV) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Poly(A) polymerase catalytic subunit

EC=2.7.7.19
Alternative name(s):
Poly(A) polymerase large subunit
Short name=PAP-L
Gene names
Name:PAPL
Ordered Locus Names:CNPV129
OrganismCanarypox virus (CNPV)
Taxonomic identifier44088 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeAvipoxvirus
Virus hostSerinus [TaxID: 9134]

Protein attributes

Sequence length472 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activity

ATP + RNA(n) = diphosphate + RNA(n+1).

Subunit structure

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Sequence similarities

Belongs to the poxviridae poly(A) polymerase catalytic subunit family.

Ontologies

Keywords
   Biological processmRNA processing
Transcription
   LigandATP-binding
Nucleotide-binding
   Molecular functionTransferase
Gene Ontology (GO)
   Biological_processmRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

polynucleotide adenylyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 472472Poly(A) polymerase catalytic subunit
PRO_0000308926

Sites

Active site1941 By similarity
Active site1961 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6VZL8 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 5661DB73F7ED3A44

FASTA47256,015
        10         20         30         40         50         60 
MDRRNQITSV IREYLGRNPV PKEYEVLKKQ TLKLSKIINF NKDTFFFLIK KNKYTFFKDL 

        70         80         90        100        110        120 
NVSDEEIQER IDEYFTKQRR ARRLGNLLAI VELQKLLVSS FTKTLGVLTT KALEYYPSNI 

       130        140        150        160        170        180 
RLDYSFMEKI ADNILDSYNV VKPSEEVKGR HKVSDLVLHV NKIMEEYLRR HSNSCICYGS 

       190        200        210        220        230        240 
YSLHLLNKKI EYGDIDILQT NARIFLINIA FLIRFITGRC VVLLKVPFLK NYVVIHDENL 

       250        260        270        280        290        300 
NHVMDSFNIK QSTMDKIPKI MIDNMYIVDP CIQLLNTIKM FSQIDRLEDI HTKFDKLSIR 

       310        320        330        340        350        360 
LGTLLEYTRY RYSILLDSES ILDVKYKIDI QNRKIILDFK KYNLNYIKCY FFLDEDELKK 

       370        380        390        400        410        420 
LIRKTPKTDD YIDLEAVTNS EYMILNKTMY TYFSNTTLLR SKDELHPITI NALTSHALLY 

       430        440        450        460        470 
HVITKKFYDD LLGDLIRSLM IVEKVPVYEI IPRDKKRGKH TIIDIEKDVV FH 

« Hide

References

[1]"The genome of canarypox virus."
Tulman E.R., Afonso C.L., Lu Z., Zsak L., Kutish G.F., Rock D.L.
J. Virol. 78:353-366(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Isolate ATCC VR-111 / Wheatley C93.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY318871 Genomic DNA. Translation: AAR83475.1.
RefSeqNP_955152.1. NC_005309.1.

3D structure databases

ProteinModelPortalQ6VZL8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2700390.

Phylogenomic databases

ProtClustDBPHA2996.

Family and domain databases

InterProIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFPIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNetSearch...

Entry information

Entry namePAP1_CNPV
AccessionPrimary (citable) accession number: Q6VZL8
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families