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Protein

Poly(A) polymerase catalytic subunit

Gene

PAPL

Organism
Canarypox virus (CNPV)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activityi

ATP + RNA(n) = diphosphate + RNA(n+1).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei194By similarity1
Active sitei196By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processmRNA processing, Transcription
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Poly(A) polymerase catalytic subunit (EC:2.7.7.19)
Alternative name(s):
Poly(A) polymerase large subunit
Short name:
PAP-L
Gene namesi
Name:PAPL
Ordered Locus Names:CNPV129
OrganismiCanarypox virus (CNPV)
Taxonomic identifieri44088 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeAvipoxvirus
Virus hostiSerinus [TaxID: 9134]
Proteomesi
  • UP000168164 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003089261 – 472Poly(A) polymerase catalytic subunitAdd BLAST472

Interactioni

Subunit structurei

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ6VZL8.
SMRiQ6VZL8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK21315.

Family and domain databases

InterProiView protein in InterPro
IPR037265. PolyA_pol_cat_sf.
IPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxviridae_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
PfamiView protein in Pfam
PF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
PIRSFiPIRSF015693. VAC-48L_nuct. 1 hit.
SUPFAMiSSF160957. SSF160957. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6VZL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRRNQITSV IREYLGRNPV PKEYEVLKKQ TLKLSKIINF NKDTFFFLIK
60 70 80 90 100
KNKYTFFKDL NVSDEEIQER IDEYFTKQRR ARRLGNLLAI VELQKLLVSS
110 120 130 140 150
FTKTLGVLTT KALEYYPSNI RLDYSFMEKI ADNILDSYNV VKPSEEVKGR
160 170 180 190 200
HKVSDLVLHV NKIMEEYLRR HSNSCICYGS YSLHLLNKKI EYGDIDILQT
210 220 230 240 250
NARIFLINIA FLIRFITGRC VVLLKVPFLK NYVVIHDENL NHVMDSFNIK
260 270 280 290 300
QSTMDKIPKI MIDNMYIVDP CIQLLNTIKM FSQIDRLEDI HTKFDKLSIR
310 320 330 340 350
LGTLLEYTRY RYSILLDSES ILDVKYKIDI QNRKIILDFK KYNLNYIKCY
360 370 380 390 400
FFLDEDELKK LIRKTPKTDD YIDLEAVTNS EYMILNKTMY TYFSNTTLLR
410 420 430 440 450
SKDELHPITI NALTSHALLY HVITKKFYDD LLGDLIRSLM IVEKVPVYEI
460 470
IPRDKKRGKH TIIDIEKDVV FH
Length:472
Mass (Da):56,015
Last modified:July 5, 2004 - v1
Checksum:i5661DB73F7ED3A44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY318871 Genomic DNA. Translation: AAR83475.1.
RefSeqiNP_955152.1. NC_005309.1.

Genome annotation databases

GeneIDi2700390.
KEGGivg:2700390.

Similar proteinsi

Entry informationi

Entry nameiPAP1_CNPV
AccessioniPrimary (citable) accession number: Q6VZL8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 5, 2004
Last modified: November 22, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families