Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

WD repeat and FYVE domain-containing protein 3

Gene

Wdfy3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Required for selective autophagy (aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies (p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri3436 – 3496FYVE-typePROSITE-ProRule annotationAdd BLAST61

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Autophagy

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
WD repeat and FYVE domain-containing protein 3
Alternative name(s):
Beach domain, WD repeat and FYVE domain-containing protein 1
Short name:
BWF1
Gene namesi
Name:Wdfy3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1096875. Wdfy3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002426941 – 3508WD repeat and FYVE domain-containing protein 3Add BLAST3508

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1942PhosphoserineCombined sources1
Modified residuei2277PhosphoserineBy similarity1
Modified residuei2474PhosphoserineCombined sources1
Modified residuei3317PhosphoserineCombined sources1
Modified residuei3321PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ6VNB8.
PaxDbiQ6VNB8.
PeptideAtlasiQ6VNB8.
PRIDEiQ6VNB8.

PTM databases

iPTMnetiQ6VNB8.
PhosphoSitePlusiQ6VNB8.

Expressioni

Tissue specificityi

Detected in liver, kidney and testis.1 Publication

Developmental stagei

Highly expressed in fetal brain. Levels decrease after 14 days of development, and continue to decrease in newborn mice to arrive at adult levels 3 days after birth.1 Publication

Gene expression databases

BgeeiENSMUSG00000043940.
CleanExiMM_WDFY3.
ExpressionAtlasiQ6VNB8. baseline and differential.
GenevisibleiQ6VNB8. MM.

Interactioni

Subunit structurei

Interacts with ATG5 and SQSTM1. Associates with the ATG12-ATG5-ATG16L complex. Interacts with GABARAP, GABARAPL1 and GABARAPL2, and weakly with MAP1LC3C (By similarity).By similarity

Protein-protein interaction databases

BioGridi215181. 1 interactor.
IntActiQ6VNB8. 2 interactors.
STRINGi10090.ENSMUSP00000052607.

Structurei

3D structure databases

ProteinModelPortaliQ6VNB8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2513 – 2638BEACH-type PHPROSITE-ProRule annotationAdd BLAST126
Domaini2665 – 2958BEACHPROSITE-ProRule annotationAdd BLAST294
Repeati3059 – 3097WD 1Add BLAST39
Repeati3107 – 3146WD 2Add BLAST40
Repeati3149 – 3188WD 3Add BLAST40
Repeati3192 – 3236WD 4Add BLAST45
Repeati3390 – 3429WD 5Add BLAST40

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni2284 – 2963Sufficient for translocalization to p62 bodies/ALISBy similarityAdd BLAST680
Regioni2568 – 3508Interaction with SQSTM1By similarityAdd BLAST941
Regioni2963 – 3508Interaction with ATG5By similarityAdd BLAST546

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi3326 – 3331LIR6

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi472 – 475Poly-Ser4
Compositional biasi2498 – 2501Poly-Glu4

Domaini

The LIR (LC3-interacting region) motif mediates the interaction with ATG8 family proteins.By similarity

Sequence similaritiesi

Contains 1 BEACH domain.PROSITE-ProRule annotation
Contains 1 BEACH-type PH domain.PROSITE-ProRule annotation
Contains 1 FYVE-type zinc finger.PROSITE-ProRule annotation
Contains 5 WD repeats.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri3436 – 3496FYVE-typePROSITE-ProRule annotationAdd BLAST61

Keywords - Domaini

Repeat, WD repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1786. Eukaryota.
KOG1788. Eukaryota.
ENOG410XNQC. LUCA.
GeneTreeiENSGT00760000119083.
HOGENOMiHOG000017170.
HOVERGENiHBG094156.
InParanoidiQ6VNB8.
PhylomeDBiQ6VNB8.
TreeFamiTF313658.

Family and domain databases

CDDicd06071. Beach. 1 hit.
Gene3Di1.10.1540.10. 1 hit.
1.25.10.10. 3 hits.
2.130.10.10. 2 hits.
2.30.29.40. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000409. BEACH_dom.
IPR013320. ConA-like_dom.
IPR031570. DUF4704.
IPR023362. PH-BEACH_dom.
IPR011993. PH_dom-like.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
IPR000306. Znf_FYVE.
IPR017455. Znf_FYVE-rel.
IPR011011. Znf_FYVE_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF02138. Beach. 1 hit.
PF15787. DUF4704. 1 hit.
PF01363. FYVE. 1 hit.
PF14844. PH_BEACH. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM01026. Beach. 1 hit.
SM00064. FYVE. 1 hit.
SM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 3 hits.
SSF49899. SSF49899. 1 hit.
SSF50729. SSF50729. 1 hit.
SSF50978. SSF50978. 2 hits.
SSF57903. SSF57903. 1 hit.
SSF81837. SSF81837. 1 hit.
PROSITEiPS50197. BEACH. 1 hit.
PS51783. PH_BEACH. 1 hit.
PS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
PS50178. ZF_FYVE. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q6VNB8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MNMVKRIMGR PRQEECSPQD NALGLMHLRR LFTELCHPPR HMTQKEQEEK
60 70 80 90 100
LYMMLPVFNR VFGNAPPNTM TEKFSDLLQF TTQVSRLMVT EIRRRASNKS
110 120 130 140 150
TEAASRAIVQ FLEINQSEEA SRGWMLLTTI NLLASSGQKT VDCMTTMSVP
160 170 180 190 200
STLVKCLYLF FDLPHVPEAG GGAQNELPLA ERRGLLQKAF VQILVKLCSF
210 220 230 240 250
VSPAEELAQK DDLQLLFSAI TSWCPPYNLP WRKSAGEVLM TISRHGLSVN
260 270 280 290 300
VVKYIHEKEC LSTCVQNMQQ SDDLSPLEIV EMFAGLSCFL KDSSDVSQTL
310 320 330 340 350
LDDFRIWQGY NFLCDLLLRL EQGKEAECRD ALKDLVSLVT SLTTYGVSEL
360 370 380 390 400
KPAGVTTGAP FLLPGFAVPQ PAGKGHSVRN IQAFAVLQNA FLKAKTNFLA
410 420 430 440 450
QIILDAITNI YMADNANYFI LESQHTLSQF AEKISKLPEV QNKYFEMLEF
460 470 480 490 500
VVFSLNYIPC KELISVSILL KSSSSYHCSI IAMKTLLKFT RHDYIFKDVF
510 520 530 540 550
REVGLLEVMV NLLHKYAALL KDPAQALNEQ GDSRNNSSVE DQKHLALLVM
560 570 580 590 600
EALTVLLQGS NTNAGIFREF GGARCAHNIV KYPQCRQHAL MTIQQLVLSP
610 620 630 640 650
NGEDDMGTLL GLMHSAPPTE LQLKTDILRA LLSVLRESHR SRTVFRKVGG
660 670 680 690 700
FVYITSLLVA MERSLSSPPK NGWEKVSQSQ VLELLHTVFC TLTAALRYEP
710 720 730 740 750
ANSHFFKTEI QYEKLADAVR FLGCFSDLRK ISAVNVFPSN TQPFQRLLEE
760 770 780 790 800
GAVSVDSVSP TLRHCSKLFI YLYKVATDSF DSHAEQIPPC LTSESSLPSP
810 820 830 840 850
WGTPALSRKR HAFHCVSTPP VYPAKNVTDL KLQVTSSPLQ SSDAVIIHPG
860 870 880 890 900
AMLAMLDLLA SVGSVTQPEH ALDLQLAVAN ILQSLVHTER NQQVMCEAGL
910 920 930 940 950
HARLLQRCGA ALADEDHSLH PPLQRMFERL ASQALEPMVL REFLRLASPL
960 970 980 990 1000
NCGAWDKKLL KQYRVHKPSS LSFEPEMRSS VITSLEGLGS DNVFSSHEDN
1010 1020 1030 1040 1050
HYRISKSLVK SAEGSTVPLT RVKCLVSMTT PHDIRLHGSS VTPAFVEFDT
1060 1070 1080 1090 1100
SLEGFGCLFL PSLAPHNAPT NNTVTTGLTD GAVVSGMGSG ERFFPPPSGL
1110 1120 1130 1140 1150
SYSCWFCIEH FSSPPNNHPV RLLTVVRRAN SSEQHYVCLA IVLSAKDRSL
1160 1170 1180 1190 1200
IVSTKEELLQ NYVDDFSEES SFYEILPCCA RFRCGELVVE GQWHHLALLM
1210 1220 1230 1240 1250
SRGMLKNSTA ALYLDGQLVS TVKLHYVHST PGGSGSANPP VLSTVYAYVG
1260 1270 1280 1290 1300
TPPAQRQIAS LVWRLGPTHF LEEVLPPSSV TTIYELGPNY VGSFQAVCVP
1310 1320 1330 1340 1350
CKDAKSEGVT PSPVSLVAEE KVSFGLYALS VSSLTVARIR KVYNKLDSKA
1360 1370 1380 1390 1400
IAKQLGISSH ENATPVKLVH NAAGHLNGPA RTIGAALIGY LGVRTFVPKP
1410 1420 1430 1440 1450
VATTLQYIGG AAAILGLVAM ASDVEGLYAA VKALVCVVKS NPLASKEMER
1460 1470 1480 1490 1500
IKGYQLLAML LKKKRSLLNS HILHLTFSLV GTVDSGHETS IIPNSTAFQD
1510 1520 1530 1540 1550
LLCDFEVWLH APYELHLSLF EHFIELLTES SEASKNAKLM REFQLIPKLL
1560 1570 1580 1590 1600
LTLRDMSLSQ PTIAAISNVL SFLLQGFPNS NDLLRFGQFI SSTLPTFAVC
1610 1620 1630 1640 1650
EKFVVMEINN EEKPDPGAEE EFGGLVSANL ILLRNRLLDI LLKLVYTSKE
1660 1670 1680 1690 1700
KTNINLQACE ELVRTLGFDW IMMFMEEHLH PTTVTAAMRI LVVLLSNQSI
1710 1720 1730 1740 1750
LIKFKEGLSG GGWLEQTDSV LTNKIGTVLG FNVGRSAGGR STVREINRDA
1760 1770 1780 1790 1800
CHFPGFLVLQ SFLPKHTNVP ALYFLLMALF LQQPVSELPE NLQVSVPVTS
1810 1820 1830 1840 1850
SRCKQGCQFD LDSIWTFIFG VPASSGTVVS SIHNVCTESA FLLLGMLRSM
1860 1870 1880 1890 1900
LNSPWQSEEE GSWLREYPVT LMQFFRYLYH NVPDLASMWL SPDFLCALAA
1910 1920 1930 1940 1950
TVFPFNIRPY SEMVTDLDDE VGSPAEEFKA FAADTGMNRS QSEYCNVGTK
1960 1970 1980 1990 2000
TYLTNHPAKK FVFDFMRVLI IDNLCLTPAS KQTPLIDLLL EASPERSTRT
2010 2020 2030 2040 2050
QQKEFQTHVL DSVMDHLLAA DVLLGEDASL PITSGGSYQV LVNNVFYFTQ
2060 2070 2080 2090 2100
RVVDKLWQGM FNKESKLLID FIIQLIAQSK RRSQGLSLDA VYHCLNRTIL
2110 2120 2130 2140 2150
YQFSRAHKTV PQQVALLDSL RVLTVNRNLI LGPGNHDQEF ISCLAHCLIN
2160 2170 2180 2190 2200
LHAGSVEGFG LEAEARMTTW HIMIPSDIEP DGGYSQDISE GRQLLIKAVN
2210 2220 2230 2240 2250
RVWTELIHSK KQVLEELFKV SLPVNDRGHV DIALARPLIE EAGLKCWQNH
2260 2270 2280 2290 2300
LAHEKKCISR GEALVPTTQS KLSRVSSGFG LSKLTGSRRN RKESGLHKHS
2310 2320 2330 2340 2350
PSPQEISQWM FTHIAVVRDL VDTQYKEYQE RQQNALKYVT EEWCQIECEL
2360 2370 2380 2390 2400
LRERGLWGPP IGSHLDKWML EMTEGPCRMR KKMVRNDMFY NHYPYVPETE
2410 2420 2430 2440 2450
QEASVGKPAR YRRAISYDSK EYYLRLASGN PAIVQDAIVE SSEGEATQQE
2460 2470 2480 2490 2500
PEHGEDTIAK VKGLVKPPLK RSRSAPDGGD EETQEQLQDQ IAESGSIEEE
2510 2520 2530 2540 2550
EKTDNATLLR LLEEGEKIQH MYRCARVQGL DTSEGLLLFG KEHFYVIDGF
2560 2570 2580 2590 2600
TMTATREIRD IETLPPNMHE PIIPRGARQG PSQLKRTCSI FAYEDIKEVH
2610 2620 2630 2640 2650
KRRYLLQPIA VEVFSGDGRN YLLAFQKGIR NKVYQRFLAV VPSLTDSSES
2660 2670 2680 2690 2700
VSGQRPNTSV EQGSGLLSTL VGEKSVTQRW ERGEISNFQY LMHLNTLAGR
2710 2720 2730 2740 2750
SYNDLMQYPV FPWILSDYDS EEVDLTNPKT FRNLAKPMGA QTDERLAQYK
2760 2770 2780 2790 2800
KRYKDWEDPN GETPAYHYGT HYSSAMIVAS YLVRMEPFTQ IFLRLQGGHF
2810 2820 2830 2840 2850
DLADRMFHSV REAWYSASKH NMADVKELIP EFFYLPEFLF NSNNFDLGCK
2860 2870 2880 2890 2900
QNGTKLGDVI LPPWAKGDPR EFIRVHREAL ECDYVSAHLH EWIDLIFGYK
2910 2920 2930 2940 2950
QQGPAAVEAV NVFHHLFYEG QVDIYNINDP LKETATIGFI NNFGQIPKQL
2960 2970 2980 2990 3000
FKKPHPPKRV RSRLNGDNIG ISVPPGATSD KIFFHHLDNL RPSLTPVKEL
3010 3020 3030 3040 3050
KEPVGQIVCT DKGILAVEQN KVLIPPAWNK TFAWGYADLS CRLGTYESDK
3060 3070 3080 3090 3100
AVTVYECLSE WGQILCAVCP NPKLVITGGT STVVCVWEMG TSKEKAKPLT
3110 3120 3130 3140 3150
LKQALLGHTD TVTCATASLA YHIIVSGSRD RTCIIWDLNK LSFLTQLRGH
3160 3170 3180 3190 3200
RAPVSALCIN ELTGDIVSCA GTYIHVWSIN GNPIVSVNTF TGRSQQIVCC
3210 3220 3230 3240 3250
CMSEMNEWDT QNVIVTGHSD GVVRFWRMEF LQVPETPAPE PVEDLEMQEG
3260 3270 3280 3290 3300
CPEAQIGQQA QDDDSSDSET EEPSVSQDPK DTSSQPSSTS HRPRAASCRA
3310 3320 3330 3340 3350
TATWCTDSGS DDSRRWSDQL SLDEKDGFIF VNYSEGQTRA HLQGPLAHPH
3360 3370 3380 3390 3400
PNPIEARSYS RLKPGYRWER QLVFRSKLTM HTAFDRKDNT HPAEVTALGV
3410 3420 3430 3440 3450
SKDHSRILVG DSRGRVFSWS VSDQPGRSAA DHWVKDEGGD SCSGCSVRFS
3460 3470 3480 3490 3500
LTERRHHCRN CGQLFCQKCS RFQSEIKRLK ISSPVRVCQN CYYSLQHERG

AEDGPRNC
Length:3,508
Mass (Da):392,338
Last modified:July 5, 2004 - v1
Checksum:i9718CB1AABCB3B8E
GO
Isoform 2 (identifier: Q6VNB8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     782-809: Missing.
     942-3508: Missing.

Show »
Length:913
Mass (Da):102,219
Checksum:iCA4F642584736900
GO

Sequence cautioni

The sequence BAC32952 differs from that shown. Reason: Frameshift at position 34.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_019477782 – 809Missing in isoform 2. 1 PublicationAdd BLAST28
Alternative sequenceiVSP_019478942 – 3508Missing in isoform 2. 1 PublicationAdd BLAST2567

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY336569 mRNA. Translation: AAQ84516.1.
AK047077 mRNA. Translation: BAC32952.1. Frameshift.
CCDSiCCDS19473.1. [Q6VNB8-1]
RefSeqiNP_766470.2. NM_172882.3. [Q6VNB8-1]
UniGeneiMm.332522.
Mm.447999.

Genome annotation databases

EnsembliENSMUST00000053177; ENSMUSP00000052607; ENSMUSG00000043940. [Q6VNB8-1]
ENSMUST00000174698; ENSMUSP00000134541; ENSMUSG00000043940. [Q6VNB8-2]
GeneIDi72145.
KEGGimmu:72145.
UCSCiuc008yis.2. mouse. [Q6VNB8-1]
uc008yit.1. mouse. [Q6VNB8-2]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY336569 mRNA. Translation: AAQ84516.1.
AK047077 mRNA. Translation: BAC32952.1. Frameshift.
CCDSiCCDS19473.1. [Q6VNB8-1]
RefSeqiNP_766470.2. NM_172882.3. [Q6VNB8-1]
UniGeneiMm.332522.
Mm.447999.

3D structure databases

ProteinModelPortaliQ6VNB8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi215181. 1 interactor.
IntActiQ6VNB8. 2 interactors.
STRINGi10090.ENSMUSP00000052607.

PTM databases

iPTMnetiQ6VNB8.
PhosphoSitePlusiQ6VNB8.

Proteomic databases

EPDiQ6VNB8.
PaxDbiQ6VNB8.
PeptideAtlasiQ6VNB8.
PRIDEiQ6VNB8.

Protocols and materials databases

DNASUi72145.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000053177; ENSMUSP00000052607; ENSMUSG00000043940. [Q6VNB8-1]
ENSMUST00000174698; ENSMUSP00000134541; ENSMUSG00000043940. [Q6VNB8-2]
GeneIDi72145.
KEGGimmu:72145.
UCSCiuc008yis.2. mouse. [Q6VNB8-1]
uc008yit.1. mouse. [Q6VNB8-2]

Organism-specific databases

CTDi23001.
MGIiMGI:1096875. Wdfy3.

Phylogenomic databases

eggNOGiKOG1786. Eukaryota.
KOG1788. Eukaryota.
ENOG410XNQC. LUCA.
GeneTreeiENSGT00760000119083.
HOGENOMiHOG000017170.
HOVERGENiHBG094156.
InParanoidiQ6VNB8.
PhylomeDBiQ6VNB8.
TreeFamiTF313658.

Miscellaneous databases

ChiTaRSiWdfy3. mouse.
PROiQ6VNB8.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000043940.
CleanExiMM_WDFY3.
ExpressionAtlasiQ6VNB8. baseline and differential.
GenevisibleiQ6VNB8. MM.

Family and domain databases

CDDicd06071. Beach. 1 hit.
Gene3Di1.10.1540.10. 1 hit.
1.25.10.10. 3 hits.
2.130.10.10. 2 hits.
2.30.29.40. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000409. BEACH_dom.
IPR013320. ConA-like_dom.
IPR031570. DUF4704.
IPR023362. PH-BEACH_dom.
IPR011993. PH_dom-like.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
IPR000306. Znf_FYVE.
IPR017455. Znf_FYVE-rel.
IPR011011. Znf_FYVE_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF02138. Beach. 1 hit.
PF15787. DUF4704. 1 hit.
PF01363. FYVE. 1 hit.
PF14844. PH_BEACH. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM01026. Beach. 1 hit.
SM00064. FYVE. 1 hit.
SM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 3 hits.
SSF49899. SSF49899. 1 hit.
SSF50729. SSF50729. 1 hit.
SSF50978. SSF50978. 2 hits.
SSF57903. SSF57903. 1 hit.
SSF81837. SSF81837. 1 hit.
PROSITEiPS50197. BEACH. 1 hit.
PS51783. PH_BEACH. 1 hit.
PS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
PS50178. ZF_FYVE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiWDFY3_MOUSE
AccessioniPrimary (citable) accession number: Q6VNB8
Secondary accession number(s): Q8C8H7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.