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Protein

Myoglobin

Gene

mb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi60 – 601Iron (heme distal ligand)
Metal bindingi89 – 891Iron (heme proximal ligand)

GO - Molecular functioni

GO - Biological processi

  • digestive tract development Source: ZFIN
  • response to activity Source: ZFIN
  • response to hypoxia Source: ZFIN
  • vasculogenesis Source: ZFIN
Complete GO annotation...

Keywords - Molecular functioni

Muscle protein

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:mb
ORF Names:zgc:65819
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 1

Organism-specific databases

ZFINiZDB-GENE-040426-1430. mb.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 147146MyoglobinPRO_0000053360Add
BLAST

Proteomic databases

PaxDbiQ6VN46.

Expressioni

Gene expression databases

BgeeiENSDARG00000031952.
ExpressionAtlasiQ6VN46. differential.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000120260.

Structurei

3D structure databases

ProteinModelPortaliQ6VN46.
SMRiQ6VN46. Positions 2-147.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3378. Eukaryota.
COG1018. LUCA.
GeneTreeiENSGT00730000110844.
HOGENOMiHOG000070111.
HOVERGENiHBG107340.
InParanoidiQ6VN46.
OMAiKKKGQHE.
OrthoDBiEOG091G0OAO.
PhylomeDBiQ6VN46.
TreeFamiTF332967.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6VN46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADHDLVLKC WGAVEADYAA NGGEVLNRLF KEYPDTLKLF PKFSGISQGD
60 70 80 90 100
LAGSPAVAAH GATVLKKLGE LLKAKGDHAA LLKPLANTHA NIHKVALNNF
110 120 130 140
RLITEVLVKV MAEKAGLDAA GQGALRRVMD AVIGDIDGYY KEIGFAG
Length:147
Mass (Da):15,583
Last modified:January 23, 2007 - v3
Checksum:i9866FEE18813EF9D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti137 – 1371D → G in AAR00323 (PubMed:15050521).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY337025 mRNA. Translation: AAR00323.1.
BC056727 mRNA. Translation: AAH56727.1.
BC065862 mRNA. Translation: AAH65862.1.
RefSeqiNP_956880.1. NM_200586.1.
XP_005160224.1. XM_005160167.2.
XP_005160225.1. XM_005160168.2.
UniGeneiDr.76034.

Genome annotation databases

EnsembliENSDART00000039807; ENSDARP00000039806; ENSDARG00000031952.
ENSDART00000133472; ENSDARP00000116402; ENSDARG00000031952.
ENSDART00000136378; ENSDARP00000120315; ENSDARG00000031952.
ENSDART00000138070; ENSDARP00000120260; ENSDARG00000031952.
GeneIDi393558.
KEGGidre:393558.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY337025 mRNA. Translation: AAR00323.1.
BC056727 mRNA. Translation: AAH56727.1.
BC065862 mRNA. Translation: AAH65862.1.
RefSeqiNP_956880.1. NM_200586.1.
XP_005160224.1. XM_005160167.2.
XP_005160225.1. XM_005160168.2.
UniGeneiDr.76034.

3D structure databases

ProteinModelPortaliQ6VN46.
SMRiQ6VN46. Positions 2-147.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000120260.

Proteomic databases

PaxDbiQ6VN46.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000039807; ENSDARP00000039806; ENSDARG00000031952.
ENSDART00000133472; ENSDARP00000116402; ENSDARG00000031952.
ENSDART00000136378; ENSDARP00000120315; ENSDARG00000031952.
ENSDART00000138070; ENSDARP00000120260; ENSDARG00000031952.
GeneIDi393558.
KEGGidre:393558.

Organism-specific databases

CTDi4151.
ZFINiZDB-GENE-040426-1430. mb.

Phylogenomic databases

eggNOGiKOG3378. Eukaryota.
COG1018. LUCA.
GeneTreeiENSGT00730000110844.
HOGENOMiHOG000070111.
HOVERGENiHBG107340.
InParanoidiQ6VN46.
OMAiKKKGQHE.
OrthoDBiEOG091G0OAO.
PhylomeDBiQ6VN46.
TreeFamiTF332967.

Miscellaneous databases

PROiQ6VN46.

Gene expression databases

BgeeiENSDARG00000031952.
ExpressionAtlasiQ6VN46. differential.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMYG_DANRE
AccessioniPrimary (citable) accession number: Q6VN46
Secondary accession number(s): Q6P028
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2004
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 82 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.