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Q6VN45

- Q6VN45_MACEU

UniProt

Q6VN45 - Q6VN45_MACEU

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Protein
Submitted name:

Transcription factor Otx2

Gene
Otx2
Organism
Macropus eugenii (Tammar wallaby)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl

GO - Biological processi

  1. axon guidance Source: Ensembl
  2. cell fate specification Source: Ensembl
  3. diencephalon morphogenesis Source: Ensembl
  4. dorsal/ventral pattern formation Source: Ensembl
  5. endoderm development Source: Ensembl
  6. eye photoreceptor cell fate commitment Source: Ensembl
  7. inner ear morphogenesis Source: Ensembl
  8. metencephalon development Source: Ensembl
  9. midbrain development Source: Ensembl
  10. primitive streak formation Source: Ensembl
  11. protein complex assembly Source: Ensembl
  12. somite rostral/caudal axis specification Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor Otx2Imported
Gene namesi
Name:Otx2Imported
OrganismiMacropus eugenii (Tammar wallaby)Imported
Taxonomic identifieri9315 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDiprotodontiaMacropodidaeMacropus

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. growth cone Source: Ensembl
  3. nucleus Source: Ensembl
  4. protein complex Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00750000117284.
HOGENOMiHOG000082677.
HOVERGENiHBG004028.
OrthoDBiEOG74J98P.
TreeFamiTF351179.

Family and domain databases

InterProiIPR003022. Otx2_TF.
IPR003025. Otx_TF.
IPR013851. Otx_TF_C.
[Graphical view]
PfamiPF03529. TF_Otx. 1 hit.
[Graphical view]
PRINTSiPR01257. OTX2HOMEOBOX.
PR01255. OTXHOMEOBOX.

Sequencei

Sequence statusi: Fragment.

Q6VN45-1 [UniParc]FASTAAdd to Basket

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RAKCRQQQQQ QQNGGQNKVR PAKKKSSPVR EVSSESGTSG QFTPPSSTSV    50
PAISSSSAPV SIWSPASISP LSDPLSTSSS CMQRSYPMTY TQASGYSQGY 100
AGSTSYFGGM DCGSYLTPMH HQLPGPGATL SPMGTNAVTS HLNQSTASLT 150
TQGYGASSLG FNSTTDCLDY KDQTASWKLN FNA 183
Length:183
Mass (Da):19,241
Last modified:July 5, 2004 - v1
Checksum:i2CA0A91D4BFFC941
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei183 – 1831Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY337233 Genomic DNA. Translation: AAQ73531.1.

Genome annotation databases

EnsembliENSMEUT00000000823; ENSMEUP00000000761; ENSMEUG00000000827.
ENSMEUT00000000829; ENSMEUP00000000765; ENSMEUG00000000827.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY337233 Genomic DNA. Translation: AAQ73531.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMEUT00000000823 ; ENSMEUP00000000761 ; ENSMEUG00000000827 .
ENSMEUT00000000829 ; ENSMEUP00000000765 ; ENSMEUG00000000827 .

Phylogenomic databases

GeneTreei ENSGT00750000117284.
HOGENOMi HOG000082677.
HOVERGENi HBG004028.
OrthoDBi EOG74J98P.
TreeFami TF351179.

Family and domain databases

InterProi IPR003022. Otx2_TF.
IPR003025. Otx_TF.
IPR013851. Otx_TF_C.
[Graphical view ]
Pfami PF03529. TF_Otx. 1 hit.
[Graphical view ]
PRINTSi PR01257. OTX2HOMEOBOX.
PR01255. OTXHOMEOBOX.
ProtoNeti Search...

Publicationsi

  1. "Structural evolution of Otx genes in craniates."
    Germot A., Lecointre G., Plouhinec J.L., Le Mentec C., Girardot F., Mazan S.
    Mol. Biol. Evol. 18:1668-1678(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The mammalian Crx genes are highly divergent representatives of the Otx5 gene family, a gnathostome orthology class of orthodenticle-related homeogenes involved in the differentiation of retinal photoreceptors and circadian entrainment."
    Plouhinec J.L., Sauka-Spengler T., Germot A., Le Mentec C., Cabana T., Harrison G., Pieau C., Sire J.Y., Veron G., Mazan S.
    Mol. Biol. Evol. 20:513-521(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6VN45_MACEU
AccessioniPrimary (citable) accession number: Q6VN45
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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