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Q6VN45

- Q6VN45_MACEU

UniProt

Q6VN45 - Q6VN45_MACEU

Protein
Submitted name:

Transcription factor Otx2

Gene

Otx2

Organism
Macropus eugenii (Tammar wallaby)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl

    GO - Biological processi

    1. axon guidance Source: Ensembl
    2. cell fate specification Source: Ensembl
    3. diencephalon morphogenesis Source: Ensembl
    4. dorsal/ventral pattern formation Source: Ensembl
    5. endoderm development Source: Ensembl
    6. eye photoreceptor cell fate commitment Source: Ensembl
    7. inner ear morphogenesis Source: Ensembl
    8. metencephalon development Source: Ensembl
    9. midbrain development Source: Ensembl
    10. primitive streak formation Source: Ensembl
    11. protein complex assembly Source: Ensembl
    12. somite rostral/caudal axis specification Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Transcription factor Otx2Imported
    Gene namesi
    Name:Otx2Imported
    OrganismiMacropus eugenii (Tammar wallaby)Imported
    Taxonomic identifieri9315 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDiprotodontiaMacropodidaeMacropus

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. growth cone Source: Ensembl
    3. nucleus Source: Ensembl
    4. protein complex Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00750000117284.
    HOGENOMiHOG000082677.
    HOVERGENiHBG004028.
    OrthoDBiEOG74J98P.
    TreeFamiTF351179.

    Family and domain databases

    InterProiIPR003022. Otx2_TF.
    IPR003025. Otx_TF.
    IPR013851. Otx_TF_C.
    [Graphical view]
    PfamiPF03529. TF_Otx. 1 hit.
    [Graphical view]
    PRINTSiPR01257. OTX2HOMEOBOX.
    PR01255. OTXHOMEOBOX.

    Sequencei

    Sequence statusi: Fragment.

    Q6VN45-1 [UniParc]FASTAAdd to Basket

    « Hide

    RAKCRQQQQQ QQNGGQNKVR PAKKKSSPVR EVSSESGTSG QFTPPSSTSV    50
    PAISSSSAPV SIWSPASISP LSDPLSTSSS CMQRSYPMTY TQASGYSQGY 100
    AGSTSYFGGM DCGSYLTPMH HQLPGPGATL SPMGTNAVTS HLNQSTASLT 150
    TQGYGASSLG FNSTTDCLDY KDQTASWKLN FNA 183
    Length:183
    Mass (Da):19,241
    Last modified:July 5, 2004 - v1
    Checksum:i2CA0A91D4BFFC941
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei183 – 1831Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY337233 Genomic DNA. Translation: AAQ73531.1.

    Genome annotation databases

    EnsembliENSMEUT00000000823; ENSMEUP00000000761; ENSMEUG00000000827.
    ENSMEUT00000000829; ENSMEUP00000000765; ENSMEUG00000000827.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY337233 Genomic DNA. Translation: AAQ73531.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMEUT00000000823 ; ENSMEUP00000000761 ; ENSMEUG00000000827 .
    ENSMEUT00000000829 ; ENSMEUP00000000765 ; ENSMEUG00000000827 .

    Phylogenomic databases

    GeneTreei ENSGT00750000117284.
    HOGENOMi HOG000082677.
    HOVERGENi HBG004028.
    OrthoDBi EOG74J98P.
    TreeFami TF351179.

    Family and domain databases

    InterProi IPR003022. Otx2_TF.
    IPR003025. Otx_TF.
    IPR013851. Otx_TF_C.
    [Graphical view ]
    Pfami PF03529. TF_Otx. 1 hit.
    [Graphical view ]
    PRINTSi PR01257. OTX2HOMEOBOX.
    PR01255. OTXHOMEOBOX.
    ProtoNeti Search...

    Publicationsi

    1. "Structural evolution of Otx genes in craniates."
      Germot A., Lecointre G., Plouhinec J.L., Le Mentec C., Girardot F., Mazan S.
      Mol. Biol. Evol. 18:1668-1678(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "The mammalian Crx genes are highly divergent representatives of the Otx5 gene family, a gnathostome orthology class of orthodenticle-related homeogenes involved in the differentiation of retinal photoreceptors and circadian entrainment."
      Plouhinec J.L., Sauka-Spengler T., Germot A., Le Mentec C., Cabana T., Harrison G., Pieau C., Sire J.Y., Veron G., Mazan S.
      Mol. Biol. Evol. 20:513-521(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ6VN45_MACEU
    AccessioniPrimary (citable) accession number: Q6VN45
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)