Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Mutant mismatch repair protein

Gene

MSH2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mutant mismatch repair proteinImported
Gene namesi
Name:MSH2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ6VBB7.

Structurei

3D structure databases

ProteinModelPortaliQ6VBB7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR007860. DNA_mmatch_repair_MutS_con_dom.
[Graphical view]
PfamiPF05188. MutS_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6VBB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SPGNLSQFED ILFGNNDMSA SIGVVGVKMS AVDGQRQVGV GYVDSIQKKL
60 70 80 90
GLCEFPDNDQ FSNLEALLIQ IGPKECVLPG GETAGDMGKL RQ
Length:92
Mass (Da):9,744
Last modified:July 5, 2004 - v1
Checksum:i9933C10076E1E1E2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei92 – 921Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY344477 Genomic DNA. Translation: AAQ23475.1.
UniGeneiHs.597656.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY344477 Genomic DNA. Translation: AAQ23475.1.
UniGeneiHs.597656.

3D structure databases

ProteinModelPortaliQ6VBB7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ6VBB7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

ChiTaRSiMSH2. human.

Family and domain databases

InterProiIPR007860. DNA_mmatch_repair_MutS_con_dom.
[Graphical view]
PfamiPF05188. MutS_II. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Human mutator hMSH2 gene exon 3 missense mutation in an early onset rectal cancer patient."
    Rajkumar T., Soumittra N., Nirmala N.K., Pandey D., Mahajan V.
    Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6VBB7_HUMAN
AccessioniPrimary (citable) accession number: Q6VBB7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.