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Q6V1P9

- PCD23_HUMAN

UniProt

Q6V1P9 - PCD23_HUMAN

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Protein

Protocadherin-23

Gene
DCHS2, CDH27, CDHJ, PCDH23, PCDHJ
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

Calcium-dependent cell-adhesion protein By similarity.

GO - Molecular functioni

  1. calcium ion binding Source: InterPro

GO - Biological processi

  1. homophilic cell adhesion Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Cell adhesion

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Recommended name:
Protocadherin-23
Alternative name(s):
Cadherin-27
Cadherin-like protein CDHJ
Cadherin-like protein VR8
Protein dachsous homolog 2
Protocadherin PCDHJ
Gene namesi
Name:DCHS2
Synonyms:CDH27, CDHJ, PCDH23, PCDHJ
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 4

Organism-specific databases

HGNCiHGNC:23111. DCHS2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei2541 – 256121Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134953793.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 29162916Protocadherin-23PRO_0000343410Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi220 – 2201N-linked (GlcNAc...) Reviewed prediction
Glycosylationi245 – 2451N-linked (GlcNAc...) Reviewed prediction
Glycosylationi406 – 4061N-linked (GlcNAc...) Reviewed prediction
Glycosylationi467 – 4671N-linked (GlcNAc...) Reviewed prediction
Glycosylationi539 – 5391N-linked (GlcNAc...) Reviewed prediction
Glycosylationi673 – 6731N-linked (GlcNAc...) Reviewed prediction
Glycosylationi820 – 8201N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1032 – 10321N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1140 – 11401N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1209 – 12091N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1443 – 14431N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1599 – 15991N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1615 – 16151N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1874 – 18741N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2024 – 20241N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2042 – 20421N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2100 – 21001N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2209 – 22091N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2474 – 24741N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2522 – 25221N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2635 – 26351N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ6V1P9.
PRIDEiQ6V1P9.

PTM databases

PhosphoSiteiQ6V1P9.

Expressioni

Tissue specificityi

Cerebral cortex and testis.1 Publication

Gene expression databases

ArrayExpressiQ6V1P9.
BgeeiQ6V1P9.
CleanExiHS_DCHS2.
GenevestigatoriQ6V1P9.

Interactioni

Protein-protein interaction databases

BioGridi120157. 1 interaction.
STRINGi9606.ENSP00000349768.

Structurei

3D structure databases

ProteinModelPortaliQ6V1P9.
SMRiQ6V1P9. Positions 58-240, 380-2516.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini56 – 177122Cadherin 1Add
BLAST
Domaini178 – 382205Cadherin 2Add
BLAST
Domaini378 – 480103Cadherin 3Add
BLAST
Domaini481 – 583103Cadherin 4Add
BLAST
Domaini586 – 692107Cadherin 5Add
BLAST
Domaini693 – 839147Cadherin 6Add
BLAST
Domaini844 – 960117Cadherin 7Add
BLAST
Domaini949 – 1055107Cadherin 8Add
BLAST
Domaini1056 – 1165110Cadherin 9Add
BLAST
Domaini1165 – 1269105Cadherin 10Add
BLAST
Domaini1270 – 1374105Cadherin 11Add
BLAST
Domaini1375 – 1478104Cadherin 12Add
BLAST
Domaini1479 – 1583105Cadherin 13Add
BLAST
Domaini1584 – 1685102Cadherin 14Add
BLAST
Domaini1685 – 1787103Cadherin 15Add
BLAST
Domaini1788 – 1892105Cadherin 16Add
BLAST
Domaini1892 – 1992101Cadherin 17Add
BLAST
Domaini1993 – 2094102Cadherin 18Add
BLAST
Domaini2095 – 2210116Cadherin 19Add
BLAST
Domaini2211 – 2314104Cadherin 20Add
BLAST
Domaini2315 – 2425111Cadherin 21Add
BLAST
Domaini2426 – 2533108Cadherin 22Add
BLAST

Sequence similaritiesi

Contains 22 cadherin domains.

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000115466.
HOVERGENiHBG053522.
InParanoidiQ6V1P9.
KOiK16507.
OMAiDKDGHFE.
OrthoDBiEOG75TM9Z.
PhylomeDBiQ6V1P9.
TreeFamiTF330641.

Family and domain databases

Gene3Di2.60.40.60. 24 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
[Graphical view]
PfamiPF00028. Cadherin. 17 hits.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 21 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 23 hits.
PROSITEiPS00232. CADHERIN_1. 13 hits.
PS50268. CADHERIN_2. 22 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Note: Additional isoforms seem to exist.

Isoform 1 (identifier: Q6V1P9-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MRLDEITKSE NEDGEKKMFT QQFESTDACV YEVYVKINSI VKSQSQCGLK     50
RGSPETELWG AIVFRSQEEN AKPVKETEVT ASDADSGLYG FIEYSLYDGF 100
LSYEAPQAFR IDPHDGQICV SQDIDRERDP ATYDLLVEAK DGDEQRMTHL 150
ALVKGGLSAQ AFVRVDLEDV NDNHPVFNPS TYVTSISDET QPGTEIINVL 200
ATDQDSGIYG TVAYELIPGN VSSLFTIDST TGLYSPEVEI LSAVNFSADK 250
EVMNSLEMFL PLLRHFKKVE RDEEAAEKKF EASRGWFMRF KGRRHLHYLK 300
VQDEAASADG EAAARYVANL AKILGEGIIY LTLPLSHLES TTLSLMVSAQ 350
DGGGLTAVIN ADVTIHIFQT TLAPAEFERP KYTFLVYEDV PEDSPIGTVK 400
AREPLNSSEP IFYRISSGDL GGKFSIHPRL GTIRTRKPLD HETQPVVVLT 450
VQAQLGSAPA CSSTEVNITV MDVNDNHPAF LRTSDEIRIS QTTPPGTALY 500
LARAEDRDSG RNGLIRYSIA SPQPGVFAID RALGVLFLNG SLGAGEQREL 550
TLTLRAEDQG VHPQAALLVL TVVIEKREHS PSWTFEHLVY QVEVSESLSP 600
MTQMLQTQAH PLGPQRAASP LRYSLEPSVD SAMFGIRPYT GWIYLRRQFD 650
YESTQTYNFR VFAWIPEDGF LQNVSTTVIV RVWDENDNSP TFLHDVLFLK 700
VEESPVPQGV IGKITAIDMD SGKNGQLLYF LLSDGKFFKM NPNTGPAGTI 750
YVITWADGAA AFSGTDFAFS SDELQAFVLK SLFCELGEGE LINWVALDRE 800
HRGHHEMTVL VTDRGSPPRN ATMAVYVSVT DINDNRPFFP QCLPGKELHV 850
KVLEGQPVNM LVTTVFAKDP DEGNNAEVTY SVSSEDSSDH FKIDANNGEI 900
RTTTILSYDY RPSYRMSVIA TDQGVPPLQG QAVVNIQVIP LSKGRAIMSQ 950
NIRHLIIPEN LKPTKIMSLI KSSDHLQQHY NGKLHFSIVA DDKDGHFEID 1000
SSTGDLFLSK ELDYETTSHY LFRVITTDHS KNLSLSSTVF LSIDVEDQND 1050
HSPSFQDELI VISVEENVPI GTLVYVFNAK DDDGSFLNSR IQYYIESHNP 1100
GTNPFLIHPS FGTLVTVSRL DRESIPTVIL TVTASDQAVN VTDRRLRSLT 1150
AQIVILDVND HNPTFISFPN AHVKEDVTVG SLVHHITAHD PDEGRNGKVT 1200
YSILSGNENM TFMLDESSGL LTTTCPLDYE MKTQHILTVL ALDDGTPALS 1250
SSQTLTVTVL DVNDEAPVFK QHLYEASVKE NQNPGEFVTR VEALDRDSGV 1300
NSKLQFEIMP GASFELFEIN SDTGEVVTTT ILDREIQEVF TLRVLVRDGG 1350
FPSLSSTTTI LCTVEDENDH APEFIVSSYD IEVLENQEPE VVYTVLASDM 1400
DAGNNRAVEY HIIDGNTDEC FTINEMSGEL STTRALDREQ ISNFTLVILC 1450
SDLGDPPRSS VIHLQVRVLD ANDHSPSFPT LYYQSSVRED AEVGTVVLVL 1500
SAVDKDEGLN GQTEYFLTDE ASGAFTIDPM SGTLKTSNTL DREARSQHTF 1550
SAVARDCSIQ GSRSTTVIIK VYVTDVNDND PVLEQNPFDV FLSPESPTNQ 1600
TTVIVRADDL DLGPNGTVVF SFAETQSMFS IDKYTGEIQF QQNPSSEYFP 1650
IWLQLKVTDQ GIPARTTTGL LVIHMEGEDV KISFSHHLYK GLVTENCEAG 1700
TSIVTVKAFA PDSIQDSMKY SIFSGNEDGV LSLCSKSGQL TVKEPKFLDF 1750
EVRNEVQLIV LAESSGHRAY CKVAVLIQDE NDNSPCFEQS IYQASVSESQ 1800
LYNAHVIQVF ATDLDSGLNG LIEYSILSGN QEEAFQIDAL SGVITTKAIL 1850
DYELTSSYSL IVQATDKGMP RLSNTTVIKV QVTDINDNAP AFLPSEAVEI 1900
TEDSLPGVIV THVSVHDVDL NSAFIFSFAK ESNPGTKFAI DQNTGVVVLV 1950
KTLDFEEMTE YELLIQISDS VHYTEGALVV RVLDVNDNPP VFSQDFYQVT 2000
VPESIPVGYS VLTLSATDLE SNENISYRIL SSSKEFSIDP KNGTIFTISP 2050
VLLLDTISTT QFLVEASDGG NPDLRALTLV EIGIEDMNNY APEFTVKSYN 2100
LSLSEDALVG STLVTFSNID HDWTRENTYV EYSIISGNSQ NNFHVETKFF 2150
HSEYPYKQVG YLVLLHSLDR EASASHELVI LASDSGCPPL SSTAVISIQV 2200
LDVNDNPPNF SSLSYHTHVK ESTPLGSHIT VVSANDRDTG SHAEIIYNII 2250
SGNEKGHFYL EENTGVLYLI KPLDYEKMTK FTLTVQASDA EKKHFSFAVV 2300
FVSVLDDNDH APQFMFSSFS CIVPENLPIS STICSINALD FDAGPYGELT 2350
YSIVSPCFLT HGMSYDHDLF LIDPLTGDIH AKQILDYENG NKYCLTVQAK 2400
DKGDATASLV VWVDIEGIDE FEPIFTQDQY FFTLPEKNKD RQLIGRVEAS 2450
DADAGIDGVI LYSLGTSSPF FSVNKTNGNI YLIRALPLIK SQLNKEDTLE 2500
MKIIAHSPKS DSKFASCTVF VNVSFSSEGT PLAVFASSFS ISLVVSFLVF 2550
LILICILIVM ILRHKQKDTI NNYEEKKTSS LDADLRVTRD ASVLKAFQKT 2600
DDCSNEVVPV DATPEWLSLI SIMEKDIVNL YRHSNSSGHC SVEGETAEDK 2650
EIQRINEHPY RKCSDSALSD HESRVPDSGI PRDSDQLSCL SGETDVMVTA 2700
ETAEASQTFG EGDQGEGCST TCAQNNVLPQ TVQKREAKES ILADVRKESV 2750
FISGDQEVRC AALSTQTTSD HDGKDNYHWN YLLSWEPKFQ PLASVFNDIA 2800
KLKDEHLHMP GIPKEKKSFV FPPPLITAVA QPGIKAVPPR MPAVNLGQVP 2850
PKHPRSPIPY HLGSLPEGMT PNFSPSLSLL TMQPPALSPL LREGELLGTH 2900
ISGTCHELKA EDEVQI 2916
Length:2,916
Mass (Da):322,234
Last modified:July 5, 2004 - v1
Checksum:i25B2F4496468ABB5
GO
Isoform 4 (identifier: Q6V1P9-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-78: MRLDEITKSE...ENAKPVKETE → MSPCGRKMGE...HAPVGHCFLQ
     143-154: Missing.
     232-326: Missing.
     745-788: Missing.
     885-914: EDSSDHFKIDANNGEIRTTTILSYDYRPSY → ARHMPLKGKTAFGKQSCKKTNKQTNKILT
     915-2916: Missing.

Note: Ref.2 (BAC87093) sequence is in conflict in positions: 446:C->G, 1358:K->KQ and differs from that shown due to a frameshift in position 1364.

Show »
Length:1,368
Mass (Da):149,191
Checksum:i8BBD22FA06CE9263
GO

Sequence cautioni

The sequence BAA90911.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence AAY41019.1 differs from that shown. Reason: Erroneous gene model prediction.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti153 – 1531V → A.
Corresponds to variant rs11721758 [ dbSNP | Ensembl ].
VAR_044362
Natural varianti174 – 1741H → R.1 Publication
Corresponds to variant rs10017772 [ dbSNP | Ensembl ].
VAR_044363
Natural varianti344 – 3441S → L.2 Publications
Corresponds to variant rs6858712 [ dbSNP | Ensembl ].
VAR_044364
Natural varianti827 – 8271V → I.
Corresponds to variant rs7666283 [ dbSNP | Ensembl ].
VAR_044365
Natural varianti897 – 8971N → S.
Corresponds to variant rs1352714 [ dbSNP | Ensembl ].
VAR_044366
Natural varianti1205 – 12051S → L.
Corresponds to variant rs11935573 [ dbSNP | Ensembl ].
VAR_044367
Natural varianti1480 – 14801T → R.
Corresponds to variant rs17031394 [ dbSNP | Ensembl ].
VAR_044368
Natural varianti1595 – 15951E → Q.
Corresponds to variant rs28561984 [ dbSNP | Ensembl ].
VAR_061075
Natural varianti2112 – 21121T → M.
Corresponds to variant rs17031279 [ dbSNP | Ensembl ].
VAR_044369
Natural varianti2303 – 23031S → N.
Corresponds to variant rs6824133 [ dbSNP | Ensembl ].
VAR_044370

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 7878MRLDE…VKETE → MSPCGRKMGEGRQQQRAPVG KLLLLPGRRDTPHGRSGSSG ARTQRSLLWLLVHVWLWAAS GSSAQLFNLTLSVDEGLPPD TLVGDIRAGLPAAQQQEGSG FFLSEDSDDSPLLDDFHVHP DTGIIRTARRLDRERRDHYS FVAATLLGAVVQVEIRVNDV NDHSPRFPLDSLQLDVSELS PPGTAFRLPGAHDPDAGLFS TQGYTLVQPSDLPKDPAGPF FQLRYRTPGPLPSPLLPGSS SPLEPLDLVLLRRLDREEAA AHRLQIEAWDGGRPRRTGLL SVELRVLDENDNPPVFEQDE YRAAVREDAQPGAEVCRVRA TDRDLGPNGFVRYSVRARQV PGAGSGGGALGDAAYFAVEE LSGVVRVWRPLDREAQAWHQ LVVEARDGGAEPEVATVRVS IAVLDVNDNRPAIHVLFLTE GGVARVSEGARPGDYVARVS VSDADCDWEKEDEATGELGV GLGDGSISLSLEGGEGDFAL LPGGPPGVFFLCVEGPLDRE SRDLYELLLVATDAGSPPLS TEETLLLRVADLNDQPPLFS QQHYKASVSEAAAPGTVVMW VSASDADEAGSDHAWLRYTV VQLSAPCNLGSLESKMVHTA ECGPSFAIDSESGVISTIRA LDREVQEAVELKVVAQDLGE PPLSATCLVSITVDDVNDNE PIFWRQVYNATIAEHAPVGH CFLQ in isoform 4. VSP_034586Add
BLAST
Alternative sequencei143 – 15412Missing in isoform 4. VSP_034587Add
BLAST
Alternative sequencei232 – 32695Missing in isoform 4. VSP_034588Add
BLAST
Alternative sequencei745 – 78844Missing in isoform 4. VSP_034589Add
BLAST
Alternative sequencei885 – 91430EDSSD…YRPSY → ARHMPLKGKTAFGKQSCKKT NKQTNKILT in isoform 4. VSP_046654Add
BLAST
Alternative sequencei915 – 29162002Missing in isoform 4. VSP_046655Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti2061 – 20611Q → R in BAA90911. 1 Publication
Sequence conflicti2074 – 20741L → P in BAA90911. 1 Publication
Sequence conflicti2475 – 24751K → R in BAA90911. 1 Publication
Sequence conflicti2633 – 26331H → Y in BAA90911. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY354497 mRNA. Translation: AAR10443.1.
AK000054 mRNA. Translation: BAA90911.1. Different initiation.
AK127704 mRNA. Translation: BAC87093.1. Frameshift.
AC079298 Genomic DNA. Translation: AAY41019.1. Sequence problems.
AC110608 Genomic DNA. No translation available.
AC110775 Genomic DNA. No translation available.
BC140919 mRNA. Translation: AAI40920.1.
CCDSiCCDS3785.1. [Q6V1P9-1]
RefSeqiNP_001136024.1. NM_001142552.1.
NP_060109.2. NM_017639.3. [Q6V1P9-1]
UniGeneiHs.655664.

Genome annotation databases

EnsembliENST00000339452; ENSP00000345062; ENSG00000197410. [Q6V1P9-4]
ENST00000357232; ENSP00000349768; ENSG00000197410. [Q6V1P9-1]
GeneIDi54798.
KEGGihsa:54798.
UCSCiuc003inw.2. human. [Q6V1P9-1]

Polymorphism databases

DMDMi74762378.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY354497 mRNA. Translation: AAR10443.1 .
AK000054 mRNA. Translation: BAA90911.1 . Different initiation.
AK127704 mRNA. Translation: BAC87093.1 . Frameshift.
AC079298 Genomic DNA. Translation: AAY41019.1 . Sequence problems.
AC110608 Genomic DNA. No translation available.
AC110775 Genomic DNA. No translation available.
BC140919 mRNA. Translation: AAI40920.1 .
CCDSi CCDS3785.1. [Q6V1P9-1 ]
RefSeqi NP_001136024.1. NM_001142552.1.
NP_060109.2. NM_017639.3. [Q6V1P9-1 ]
UniGenei Hs.655664.

3D structure databases

ProteinModelPortali Q6V1P9.
SMRi Q6V1P9. Positions 58-240, 380-2516.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 120157. 1 interaction.
STRINGi 9606.ENSP00000349768.

PTM databases

PhosphoSitei Q6V1P9.

Polymorphism databases

DMDMi 74762378.

Proteomic databases

PaxDbi Q6V1P9.
PRIDEi Q6V1P9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000339452 ; ENSP00000345062 ; ENSG00000197410 . [Q6V1P9-4 ]
ENST00000357232 ; ENSP00000349768 ; ENSG00000197410 . [Q6V1P9-1 ]
GeneIDi 54798.
KEGGi hsa:54798.
UCSCi uc003inw.2. human. [Q6V1P9-1 ]

Organism-specific databases

CTDi 54798.
GeneCardsi GC04M155155.
H-InvDB HIX0004584.
HGNCi HGNC:23111. DCHS2.
MIMi 612486. gene.
neXtProti NX_Q6V1P9.
PharmGKBi PA134953793.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG12793.
HOGENOMi HOG000115466.
HOVERGENi HBG053522.
InParanoidi Q6V1P9.
KOi K16507.
OMAi DKDGHFE.
OrthoDBi EOG75TM9Z.
PhylomeDBi Q6V1P9.
TreeFami TF330641.

Miscellaneous databases

GeneWikii DCHS2.
GenomeRNAii 54798.
NextBioi 57483.
PROi Q6V1P9.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q6V1P9.
Bgeei Q6V1P9.
CleanExi HS_DCHS2.
Genevestigatori Q6V1P9.

Family and domain databases

Gene3Di 2.60.40.60. 24 hits.
InterProi IPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
[Graphical view ]
Pfami PF00028. Cadherin. 17 hits.
[Graphical view ]
PRINTSi PR00205. CADHERIN.
SMARTi SM00112. CA. 21 hits.
[Graphical view ]
SUPFAMi SSF49313. SSF49313. 23 hits.
PROSITEi PS00232. CADHERIN_1. 13 hits.
PS50268. CADHERIN_2. 22 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of new human cadherin genes using a combination of protein motif search and gene finding methods."
    Hoeng J.C., Ivanov N.V., Hodor P., Xia M., Wei N., Blevins R., Gerhold D., Borodovsky M., Liu Y.
    J. Mol. Biol. 337:307-317(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1902-2916 (ISOFORM 1), VARIANT LEU-344.
    Tissue: Colon.
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4), VARIANTS ARG-174 AND LEU-344.
    Tissue: Brain.

Entry informationi

Entry nameiPCD23_HUMAN
AccessioniPrimary (citable) accession number: Q6V1P9
Secondary accession number(s): B2RU14
, E9PC11, Q4W5P9, Q6ZS61, Q9NXU8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: July 5, 2004
Last modified: September 3, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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