ID   Q6V0K8_HUMAN            Unreviewed;       366 AA.
AC   Q6V0K8;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 92.
DE   SubName: Full=Cajalin 2 {ECO:0000313|EMBL:AAQ56189.1};
DE   Flags: Fragment;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAQ56189.1};
RN   [1] {ECO:0000313|EMBL:AAQ56189.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15862129; DOI=10.1186/1471-2121-6-23;
RA   Xu H., Hebert M.D.;
RT   "A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body
RT   protein coilin.";
RL   BMC Cell Biol. 6:23-23(2005).
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DR   EMBL; AY356353; AAQ56189.1; -; mRNA.
DR   RefSeq; NP_001191009.1; NM_001204080.1.
DR   AlphaFoldDB; Q6V0K8; -.
DR   IntAct; Q6V0K8; 1.
DR   PeptideAtlas; Q6V0K8; -.
DR   DNASU; 56899; -.
DR   GeneID; 56899; -.
DR   CTD; 56899; -.
DR   OrthoDB; 25046at2759; -.
DR   BioGRID-ORCS; 56899; 7 hits in 1138 CRISPR screens.
DR   GenomeRNAi; 56899; -.
DR   CDD; cd01274; PTB_Anks; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR033635; ANKS1/Caskin.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   PANTHER; PTHR24174; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR24174:SF3; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1B; 1.
DR   Pfam; PF00640; PID; 1.
DR   SMART; SM00462; PTB; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS01179; PID; 1.
DR   Genevisible; Q6V0K8; HS.
PE   2: Evidence at transcript level;
FT   DOMAIN          165..298
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   REGION          49..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          303..323
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..93
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        101..122
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAQ56189.1"
SQ   SEQUENCE   366 AA;  41015 MW;  3AA02088F6254D75 CRC64;
     GERRFKPHVC VLGGQSPPAL ADPGSRPARA ARVLKINLIG HRKRILASLG DRLHDDPPQK
     PPRSITLREP SGNHTPPQLS PSLSQSTYTT GGSLDVPHII MQGDARRRRN ENYFDDIPRS
     KLERQMAQTG DWGEPSITLR PPNEATASTP VQYWQHHPEK LIFQSCDYKA FYLGSMLIKE
     LRGTESTQDA CAKMRANCQK STEQMKKVPT IILSVSYKGV KFIDATNKNI IAEHEIRNIS
     CAAQDPEDLS TFAYITKDLK SNHHYCHVFT AFDVNLAYEI ILTLGQAFEV AYQLALQARK
     GGHSSTLPES FENKPSKPIP KPRVSIRKSV QIDPSEQKTL ANLPWIVEPG QEAKRGINTK
     YETTIF
//