Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6UXP3

- TM14E_HUMAN

UniProt

Q6UXP3 - TM14E_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Transmembrane protein 14E

Gene

TMEM14E

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 14E
Gene namesi
Name:TMEM14E
ORF Names:UNQ9344/PRO34067
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:34386. TMEM14E.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162405891.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 125125Transmembrane protein 14EPRO_0000348435Add
BLAST

Proteomic databases

PaxDbiQ6UXP3.
PRIDEiQ6UXP3.

Expressioni

Gene expression databases

BgeeiQ6UXP3.
CleanExiHS_TMEM14E.
GenevestigatoriQ6UXP3.

Organism-specific databases

HPAiHPA014550.

Structurei

3D structure databases

ProteinModelPortaliQ6UXP3.
SMRiQ6UXP3. Positions 4-61.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 2921HelicalSequence AnalysisAdd
BLAST
Transmembranei81 – 10121HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0136 (TMEM14) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG240787.
HOGENOMiHOG000211932.
HOVERGENiHBG066645.
InParanoidiQ6UXP3.
OMAiHEWEYEA.
OrthoDBiEOG7NKKP0.
PhylomeDBiQ6UXP3.

Family and domain databases

InterProiIPR005349. UPF0136_TM.
[Graphical view]
PANTHERiPTHR12668. PTHR12668. 1 hit.
PfamiPF03647. Tmemb_14. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6UXP3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQMDPGPQVP LYWLGFVYAA LAALGGISGY AKVGSVQSPS AGFFFSELAG
60 70 80 90 100
LDASQPSRNP KEHLSSPVYI WDLARYYANK ILTLWNIYAC GFSCRCLLIV
110 120
SKLGSMYGEQ ILSVVAMSQL GLMKN
Length:125
Mass (Da):13,608
Last modified:July 5, 2004 - v1
Checksum:iB341C0F9501B65CE
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti82 – 821L → P.
Corresponds to variant rs13077912 [ dbSNP | Ensembl ].
VAR_046161

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY358260 mRNA. Translation: AAQ88627.1.
CH471052 Genomic DNA. Translation: EAW78784.1.
CCDSiCCDS43161.1.
RefSeqiNP_001116700.1. NM_001123228.1.
UniGeneiHs.632562.

Genome annotation databases

EnsembliENST00000408960; ENSP00000386163; ENSG00000221962.
GeneIDi645843.
KEGGihsa:645843.
UCSCiuc010hvo.3. human.

Polymorphism databases

DMDMi74738233.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY358260 mRNA. Translation: AAQ88627.1 .
CH471052 Genomic DNA. Translation: EAW78784.1 .
CCDSi CCDS43161.1.
RefSeqi NP_001116700.1. NM_001123228.1.
UniGenei Hs.632562.

3D structure databases

ProteinModelPortali Q6UXP3.
SMRi Q6UXP3. Positions 4-61.
ModBasei Search...
MobiDBi Search...

Polymorphism databases

DMDMi 74738233.

Proteomic databases

PaxDbi Q6UXP3.
PRIDEi Q6UXP3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000408960 ; ENSP00000386163 ; ENSG00000221962 .
GeneIDi 645843.
KEGGi hsa:645843.
UCSCi uc010hvo.3. human.

Organism-specific databases

CTDi 645843.
GeneCardsi GC03M152057.
HGNCi HGNC:34386. TMEM14E.
HPAi HPA014550.
neXtProti NX_Q6UXP3.
PharmGKBi PA162405891.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG240787.
HOGENOMi HOG000211932.
HOVERGENi HBG066645.
InParanoidi Q6UXP3.
OMAi HEWEYEA.
OrthoDBi EOG7NKKP0.
PhylomeDBi Q6UXP3.

Miscellaneous databases

GenomeRNAii 645843.
NextBioi 118033.
PROi Q6UXP3.

Gene expression databases

Bgeei Q6UXP3.
CleanExi HS_TMEM14E.
Genevestigatori Q6UXP3.

Family and domain databases

InterProi IPR005349. UPF0136_TM.
[Graphical view ]
PANTHERi PTHR12668. PTHR12668. 1 hit.
Pfami PF03647. Tmemb_14. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiTM14E_HUMAN
AccessioniPrimary (citable) accession number: Q6UXP3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
  5. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3