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Protein

Histidine-rich carboxyl terminus protein 1

Gene

HRCT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-32332-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine-rich carboxyl terminus protein 1
Gene namesi
Name:HRCT1
ORF Names:UNQ338/PRO537
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:33872. HRCT1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 29HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000196196.
PharmGKBiPA164720718.

Polymorphism and mutation databases

BioMutaiHRCT1.
DMDMi74738206.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003176381 – 115Histidine-rich carboxyl terminus protein 1Add BLAST115

Proteomic databases

PaxDbiQ6UXD1.
PeptideAtlasiQ6UXD1.
PRIDEiQ6UXD1.

Expressioni

Gene expression databases

BgeeiENSG00000196196.
CleanExiHS_HRCT1.
GenevisibleiQ6UXD1. HS.

Organism-specific databases

HPAiHPA067038.

Structurei

3D structure databases

ProteinModelPortaliQ6UXD1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi66 – 113His-richAdd BLAST48

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J57D. Eukaryota.
ENOG411195T. LUCA.
GeneTreeiENSGT00510000049544.
HOGENOMiHOG000082439.
InParanoidiQ6UXD1.
OMAiATCLFHG.
OrthoDBiEOG091G1BYN.
PhylomeDBiQ6UXD1.

Family and domain databases

InterProiIPR031506. HRCT1.
[Graphical view]
PfamiPF15758. HRCT1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6UXD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGLLGSTAL VGWITGAAVA VLLLLLLLAT CLFHGRQDCD VERNRTAAGG
60 70 80 90 100
NRVRRAQPWP FRRRGHLGIF HHHRHPGHVS HVPNVGLHHH HHPRHTPHHL
110
HHHHHPHRHH PRHAR
Length:115
Mass (Da):13,183
Last modified:July 5, 2004 - v1
Checksum:i8EE498C8AA1DE8D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358408 mRNA. Translation: AAQ88774.1.
AL135841 Genomic DNA. Translation: CAX15137.1.
CCDSiCCDS35012.1.
RefSeqiNP_001034881.1. NM_001039792.1.
UniGeneiHs.208081.

Genome annotation databases

EnsembliENST00000354323; ENSP00000346283; ENSG00000196196.
GeneIDi646962.
KEGGihsa:646962.
UCSCiuc003zyr.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358408 mRNA. Translation: AAQ88774.1.
AL135841 Genomic DNA. Translation: CAX15137.1.
CCDSiCCDS35012.1.
RefSeqiNP_001034881.1. NM_001039792.1.
UniGeneiHs.208081.

3D structure databases

ProteinModelPortaliQ6UXD1.
ModBaseiSearch...
MobiDBiSearch...

Polymorphism and mutation databases

BioMutaiHRCT1.
DMDMi74738206.

Proteomic databases

PaxDbiQ6UXD1.
PeptideAtlasiQ6UXD1.
PRIDEiQ6UXD1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000354323; ENSP00000346283; ENSG00000196196.
GeneIDi646962.
KEGGihsa:646962.
UCSCiuc003zyr.1. human.

Organism-specific databases

CTDi646962.
GeneCardsiHRCT1.
HGNCiHGNC:33872. HRCT1.
HPAiHPA067038.
neXtProtiNX_Q6UXD1.
OpenTargetsiENSG00000196196.
PharmGKBiPA164720718.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J57D. Eukaryota.
ENOG411195T. LUCA.
GeneTreeiENSGT00510000049544.
HOGENOMiHOG000082439.
InParanoidiQ6UXD1.
OMAiATCLFHG.
OrthoDBiEOG091G1BYN.
PhylomeDBiQ6UXD1.

Enzyme and pathway databases

BioCyciZFISH:G66-32332-MONOMER.

Miscellaneous databases

GenomeRNAii646962.
PROiQ6UXD1.

Gene expression databases

BgeeiENSG00000196196.
CleanExiHS_HRCT1.
GenevisibleiQ6UXD1. HS.

Family and domain databases

InterProiIPR031506. HRCT1.
[Graphical view]
PfamiPF15758. HRCT1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHRCT1_HUMAN
AccessioniPrimary (citable) accession number: Q6UXD1
Secondary accession number(s): B7ZBJ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.