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Protein

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9

Gene

B3GNT9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Enzyme and pathway databases

ReactomeiR-HSA-913709. O-linked glycosylation of mucins.

Protein family/group databases

CAZyiGT31. Glycosyltransferase Family 31.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9Imported (EC:2.4.1.-)
Short name:
BGnT-9Imported
Short name:
Beta-1,3-Gn-T9
Short name:
Beta-1,3-N-acetylglucosaminyltransferase 9
Short name:
Beta3Gn-T9Imported
Gene namesi
Name:B3GNT9Imported
ORF Names:UNQ1922/PRO4397
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000237172.3.
HGNCiHGNC:28714. B3GNT9.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 10CytoplasmicSequence analysis10
Transmembranei11 – 27Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST17
Topological domaini28 – 402LumenalSequence analysisAdd BLAST375

Keywords - Cellular componenti

Golgi apparatus, Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi84752.
OpenTargetsiENSG00000237172.
PharmGKBiPA164716431.

Polymorphism and mutation databases

BioMutaiB3GNT9.
DMDMi74738184.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003527621 – 402UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9Add BLAST402

Proteomic databases

PaxDbiQ6UX72.
PeptideAtlasiQ6UX72.
PRIDEiQ6UX72.
TopDownProteomicsiQ6UX72.

PTM databases

iPTMnetiQ6UX72.
PhosphoSitePlusiQ6UX72.

Expressioni

Gene expression databases

BgeeiENSG00000237172.
CleanExiHS_B3GNT9.
GenevisibleiQ6UX72. HS.

Organism-specific databases

HPAiHPA052743.
HPA062734.

Interactioni

Protein-protein interaction databases

BioGridi124240. 2 interactors.
IntActiQ6UX72. 2 interactors.
STRINGi9606.ENSP00000400157.

Structurei

3D structure databases

ProteinModelPortaliQ6UX72.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 31 family.Sequence analysis

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2287. Eukaryota.
ENOG410ZZ1B. LUCA.
GeneTreeiENSGT00760000118879.
HOGENOMiHOG000232195.
HOVERGENiHBG050653.
InParanoidiQ6UX72.
KOiK18705.
OMAiFRTFGIP.
OrthoDBiEOG091G0AXM.
PhylomeDBiQ6UX72.
TreeFamiTF318639.

Family and domain databases

InterProiView protein in InterPro
IPR002659. Glyco_trans_31.
PANTHERiPTHR11214. PTHR11214. 1 hit.
PfamiView protein in Pfam
PF01762. Galactosyl_T. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6UX72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRRLRLRRD ALLTLLLGAS LGLLLYAQRD GAAPTASAPR GRGRAAPRPT
60 70 80 90 100
PGPRAFQLPD AGAAPPAYEG DTPAPPTPTG PFDFARYLRA KDQRRFPLLI
110 120 130 140 150
NQPHKCRGDG APGGRPDLLI AVKSVAEDFE RRQAVRQTWG AEGRVQGALV
160 170 180 190 200
RRVFLLGVPR GAGSGGADEV GEGARTHWRA LLRAESLAYA DILLWAFDDT
210 220 230 240 250
FFNLTLKEIH FLAWASAFCP DVRFVFKGDA DVFVNVGNLL EFLAPRDPAQ
260 270 280 290 300
DLLAGDVIVH ARPIRTRASK YYIPEAVYGL PAYPAYAGGG GFVLSGATLH
310 320 330 340 350
RLAGACAQVE LFPIDDVFLG MCLQRLRLTP EPHPAFRTFG IPQPSAAPHL
360 370 380 390 400
STFDPCFYRE LVVVHGLSAA DIWLMWRLLH GPHGPACAHP QPVAAGPFQW

DS
Length:402
Mass (Da):43,751
Last modified:July 5, 2004 - v1
Checksum:iE4FFEBDFD5F8F2FB
GO

Sequence cautioni

The sequence BC012191 differs from that shown. Reason: Frameshift at position 81.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358485 mRNA. Translation: AAQ88849.1.
CH471092 Genomic DNA. Translation: EAW83079.1.
BC012191 mRNA. No translation available.
CCDSiCCDS45509.1.
RefSeqiNP_171608.2. NM_033309.2.
UniGeneiHs.744158.

Genome annotation databases

EnsembliENST00000449549; ENSP00000400157; ENSG00000237172.
GeneIDi84752.
KEGGihsa:84752.
UCSCiuc002erf.4. human.

Similar proteinsi

Entry informationi

Entry nameiB3GN9_HUMAN
AccessioniPrimary (citable) accession number: Q6UX72
Secondary accession number(s): Q96EK0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: July 5, 2004
Last modified: September 27, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families