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Protein

Protein PET117 homolog, mitochondrial

Gene

PET117

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PET117 homolog, mitochondrial
Gene namesi
Name:PET117
ORF Names:UNQ607/PRO1194
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:40045. PET117.

Subcellular locationi

GO - Cellular componenti

  • mitochondrion Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

Pathology & Biotechi

Polymorphism and mutation databases

BioMutaiPET117.
DMDMi74738135.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2222MitochondrionSequence AnalysisAdd
BLAST
Chaini23 – 8159Protein PET117 homolog, mitochondrialPRO_0000416096Add
BLAST

Proteomic databases

MaxQBiQ6UWS5.
PRIDEiQ6UWS5.

Expressioni

Gene expression databases

BgeeiQ6UWS5.
ExpressionAtlasiQ6UWS5. baseline.

Organism-specific databases

HPAiHPA047716.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000397881.

Structurei

3D structure databases

ProteinModelPortaliQ6UWS5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PET117 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiNOG83617.
GeneTreeiENSGT00520000059926.
HOGENOMiHOG000186417.
HOVERGENiHBG063510.
InParanoidiQ6UWS5.
KOiK18188.
OMAiQNRKKEN.
OrthoDBiEOG78H3X3.
PhylomeDBiQ6UWS5.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6UWS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRSSKVVLG LSVLLTAATV AGVHVKQQWD QQRLRDGVIR DIERQIRKKE
60 70 80
NIRLLGEQII LTEQLEAERE KMLLAKGSQK S
Length:81
Mass (Da):9,223
Last modified:July 5, 2004 - v1
Checksum:i47FDC5E7BC63E87C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358666 mRNA. Translation: AAQ89029.1.
AL050321 Genomic DNA. No translation available.
CCDSiCCDS54450.1.
RefSeqiNP_001158283.1. NM_001164811.1.
UniGeneiHs.488051.

Genome annotation databases

EnsembliENST00000432901; ENSP00000397881; ENSG00000232838.
GeneIDi100303755.
KEGGihsa:100303755.
UCSCiuc021wba.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358666 mRNA. Translation: AAQ89029.1.
AL050321 Genomic DNA. No translation available.
CCDSiCCDS54450.1.
RefSeqiNP_001158283.1. NM_001164811.1.
UniGeneiHs.488051.

3D structure databases

ProteinModelPortaliQ6UWS5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000397881.

Polymorphism and mutation databases

BioMutaiPET117.
DMDMi74738135.

Proteomic databases

MaxQBiQ6UWS5.
PRIDEiQ6UWS5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000432901; ENSP00000397881; ENSG00000232838.
GeneIDi100303755.
KEGGihsa:100303755.
UCSCiuc021wba.1. human.

Organism-specific databases

CTDi100303755.
GeneCardsiGC20P018119.
HGNCiHGNC:40045. PET117.
HPAiHPA047716.
MIMi614771. gene.
neXtProtiNX_Q6UWS5.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG83617.
GeneTreeiENSGT00520000059926.
HOGENOMiHOG000186417.
HOVERGENiHBG063510.
InParanoidiQ6UWS5.
KOiK18188.
OMAiQNRKKEN.
OrthoDBiEOG78H3X3.
PhylomeDBiQ6UWS5.

Miscellaneous databases

GenomeRNAii100303755.
NextBioi34050860.
PROiQ6UWS5.
SOURCEiSearch...

Gene expression databases

BgeeiQ6UWS5.
ExpressionAtlasiQ6UWS5. baseline.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase."
    Szklarczyk R., Wanschers B.F., Cuypers T.D., Esseling J.J., Riemersma M., van den Brand M.A., Gloerich J., Lasonder E., van den Heuvel L.P., Nijtmans L.G., Huynen M.A.
    Genome Biol. 13:RESEARCH0012.1-RESEARCH0012.14(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.

Entry informationi

Entry nameiPT117_HUMAN
AccessioniPrimary (citable) accession number: Q6UWS5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: July 5, 2004
Last modified: May 27, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.