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Protein

Protein TEX261

Gene

TEX261

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein TEX261
Gene namesi
Name:TEX261
ORF Names:UNQ1882/PRO4325
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:30712. TEX261.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei3 – 2321HelicalSequence analysisAdd
BLAST
Transmembranei42 – 6221HelicalSequence analysisAdd
BLAST
Transmembranei70 – 9021HelicalSequence analysisAdd
BLAST
Transmembranei97 – 11721HelicalSequence analysisAdd
BLAST
Transmembranei125 – 14521HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134885680.

Polymorphism and mutation databases

BioMutaiTEX261.
DMDMi74749387.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 196196Protein TEX261PRO_0000247433Add
BLAST

Proteomic databases

PaxDbiQ6UWH6.
PeptideAtlasiQ6UWH6.
PRIDEiQ6UWH6.

Expressioni

Gene expression databases

BgeeiENSG00000144043.
CleanExiHS_TEX261.
ExpressionAtlasiQ6UWH6. baseline and differential.
GenevisibleiQ6UWH6. HS.

Organism-specific databases

HPAiHPA016631.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi125244. 1 interaction.
STRINGi9606.ENSP00000272438.

Structurei

3D structure databases

ProteinModelPortaliQ6UWH6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SVP26 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4136. Eukaryota.
ENOG4111MZE. LUCA.
GeneTreeiENSGT00390000010888.
HOGENOMiHOG000116065.
HOVERGENiHBG054718.
InParanoidiQ6UWH6.
OMAiMWFIYLL.
OrthoDBiEOG091G0S0I.
PhylomeDBiQ6UWH6.
TreeFamiTF324741.

Family and domain databases

InterProiIPR007277. Transmembrane_adaptor_Erv26.
[Graphical view]
PANTHERiPTHR13144. PTHR13144. 1 hit.
PfamiPF04148. Erv26. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6UWH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWFMYLLSWL SLFIQVAFIT LAVAAGLYYL AELIEEYTVA TSRIIKYMIW
60 70 80 90 100
FSTAVLIGLY VFERFPTSMI GVGLFTNLVY FGLLQTFPFI MLTSPNFILS
110 120 130 140 150
CGLVVVNHYL AFQFFAEEYY PFSEVLAYFT FCLWIIPFAF FVSLSAGENV
160 170 180 190
LPSTMQPGDD VVSNYFTKGK RGKRLGILVV FSFIKEAILP SRQKIY
Length:196
Mass (Da):22,538
Last modified:July 5, 2004 - v1
Checksum:i9DA21539B227095E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358783 mRNA. Translation: AAQ89143.1.
CH471053 Genomic DNA. Translation: EAW99783.1.
CH471053 Genomic DNA. Translation: EAW99785.1.
BC020251 mRNA. Translation: AAH20251.2.
BC128461 mRNA. Translation: AAI28462.1.
BC128462 mRNA. Translation: AAI28463.1.
CCDSiCCDS1914.1.
RefSeqiNP_653183.2. NM_144582.2.
UniGeneiHs.516087.

Genome annotation databases

EnsembliENST00000272438; ENSP00000272438; ENSG00000144043.
GeneIDi113419.
KEGGihsa:113419.
UCSCiuc002shn.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358783 mRNA. Translation: AAQ89143.1.
CH471053 Genomic DNA. Translation: EAW99783.1.
CH471053 Genomic DNA. Translation: EAW99785.1.
BC020251 mRNA. Translation: AAH20251.2.
BC128461 mRNA. Translation: AAI28462.1.
BC128462 mRNA. Translation: AAI28463.1.
CCDSiCCDS1914.1.
RefSeqiNP_653183.2. NM_144582.2.
UniGeneiHs.516087.

3D structure databases

ProteinModelPortaliQ6UWH6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125244. 1 interaction.
STRINGi9606.ENSP00000272438.

Polymorphism and mutation databases

BioMutaiTEX261.
DMDMi74749387.

Proteomic databases

PaxDbiQ6UWH6.
PeptideAtlasiQ6UWH6.
PRIDEiQ6UWH6.

Protocols and materials databases

DNASUi113419.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000272438; ENSP00000272438; ENSG00000144043.
GeneIDi113419.
KEGGihsa:113419.
UCSCiuc002shn.4. human.

Organism-specific databases

CTDi113419.
GeneCardsiTEX261.
H-InvDBHIX0029941.
HGNCiHGNC:30712. TEX261.
HPAiHPA016631.
neXtProtiNX_Q6UWH6.
PharmGKBiPA134885680.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4136. Eukaryota.
ENOG4111MZE. LUCA.
GeneTreeiENSGT00390000010888.
HOGENOMiHOG000116065.
HOVERGENiHBG054718.
InParanoidiQ6UWH6.
OMAiMWFIYLL.
OrthoDBiEOG091G0S0I.
PhylomeDBiQ6UWH6.
TreeFamiTF324741.

Miscellaneous databases

ChiTaRSiTEX261. human.
GenomeRNAii113419.
PROiQ6UWH6.

Gene expression databases

BgeeiENSG00000144043.
CleanExiHS_TEX261.
ExpressionAtlasiQ6UWH6. baseline and differential.
GenevisibleiQ6UWH6. HS.

Family and domain databases

InterProiIPR007277. Transmembrane_adaptor_Erv26.
[Graphical view]
PANTHERiPTHR13144. PTHR13144. 1 hit.
PfamiPF04148. Erv26. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTX261_HUMAN
AccessioniPrimary (citable) accession number: Q6UWH6
Secondary accession number(s): A1A587, D6W5G9, Q8WUJ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.