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Protein

Transmembrane protein C16orf54

Gene

C16orf54

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein C16orf54
Gene namesi
ORF Names:UNQ9389/PRO34280
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000185905.3.
HGNCiHGNC:26649. C16orf54.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei32 – 52HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185905.
PharmGKBiPA142672261.

Polymorphism and mutation databases

BioMutaiC16orf54.
DMDMi74738078.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002794421 – 224Transmembrane protein C16orf54Add BLAST224

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi4O-linked (GalNAc...) threonine1 Publication1
Modified residuei112PhosphothreonineBy similarity1
Modified residuei116PhosphothreonineBy similarity1
Modified residuei194PhosphoserineBy similarity1

Post-translational modificationi

O-glycosylated with core 1 or possibly core 8 glycans.1 Publication

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiQ6UWD8.
PeptideAtlasiQ6UWD8.
PRIDEiQ6UWD8.

PTM databases

iPTMnetiQ6UWD8.
PhosphoSitePlusiQ6UWD8.
UniCarbKBiQ6UWD8.

Expressioni

Gene expression databases

BgeeiENSG00000185905.
CleanExiHS_C16orf54.
GenevisibleiQ6UWD8. HS.

Organism-specific databases

HPAiHPA060546.

Interactioni

Protein-protein interaction databases

BioGridi129700. 4 interactors.
STRINGi9606.ENSP00000327506.

Structurei

3D structure databases

ProteinModelPortaliQ6UWD8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IPJ8. Eukaryota.
ENOG41115SA. LUCA.
GeneTreeiENSGT00390000014957.
HOGENOMiHOG000111899.
HOVERGENiHBG081314.
InParanoidiQ6UWD8.
OMAiPEWGLQP.
OrthoDBiEOG091G0SQ2.
PhylomeDBiQ6UWD8.
TreeFamiTF337660.

Family and domain databases

InterProiView protein in InterPro
IPR031499. DUF4689.
PANTHERiPTHR36134. PTHR36134. 1 hit.
PfamiView protein in Pfam
PF15755. DUF4689. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6UWD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLTPEPPSG RVEGPPAWEA APWPSLPCGP CIPIMLVLAT LAALFILTTA
60 70 80 90 100
VLAERLFRRA LRPDPSHRAP TLVWRPGGEL WIEPMGTARE RSEDWYGSAV
110 120 130 140 150
PLLTDRAPEP PTQVGTLEAR ATAPPAPSAP NSAPSNLGPQ TVLEVPARST
160 170 180 190 200
FWGPQPWEGR PPATGLVSWA EPEQRPEASV QFGSPQARRQ RPGSPDPEWG
210 220
LQPRVTLEQI SAFWKREGRT SVGF
Length:224
Mass (Da):24,360
Last modified:July 5, 2004 - v1
Checksum:iF3556BF216B1044B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti215K → E in BAC04015 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358833 mRNA. Translation: AAQ89192.1.
AK093000 mRNA. Translation: BAC04015.1.
CH471238 Genomic DNA. Translation: EAW80012.1.
BC104466 mRNA. Translation: AAI04467.1.
BC104467 mRNA. Translation: AAI04468.1.
CCDSiCCDS10652.1.
RefSeqiNP_787096.2. NM_175900.3.
XP_011506896.1. XM_011508594.2.
UniGeneiHs.331095.

Genome annotation databases

EnsembliENST00000329410; ENSP00000327506; ENSG00000185905.
GeneIDi105369277.
283897.
KEGGihsa:105369277.
hsa:283897.
UCSCiuc002dtp.3. human.

Similar proteinsi

Entry informationi

Entry nameiCP054_HUMAN
AccessioniPrimary (citable) accession number: Q6UWD8
Secondary accession number(s): A6NJR6, Q8NAB0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: July 5, 2004
Last modified: November 22, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM