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Q6UW78

- CK083_HUMAN

UniProt

Q6UW78 - CK083_HUMAN

Protein

UPF0723 protein C11orf83

Gene

C11orf83

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    UPF0723 protein C11orf83
    Gene namesi
    ORF Names:UNQ655/PRO1286
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:34399. C11orf83.

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162377760.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 23231 PublicationAdd
    BLAST
    Chaini24 – 9370UPF0723 protein C11orf83PRO_0000022611Add
    BLAST

    Proteomic databases

    MaxQBiQ6UW78.
    PaxDbiQ6UW78.
    PRIDEiQ6UW78.

    PTM databases

    PhosphoSiteiQ6UW78.

    Expressioni

    Gene expression databases

    BgeeiQ6UW78.
    CleanExiHS_C11orf83.
    GenevestigatoriQ6UW78.

    Organism-specific databases

    HPAiHPA046851.

    Interactioni

    Protein-protein interaction databases

    BioGridi612915. 6 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6UW78.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UPF0723 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG82939.
    HOGENOMiHOG000111740.
    InParanoidiQ6UW78.
    OMAiKEMPEQN.
    OrthoDBiEOG7992TW.
    PhylomeDBiQ6UW78.
    TreeFamiTF339744.

    Family and domain databases

    InterProiIPR027896. DUF4574.
    [Graphical view]
    PfamiPF15141. DUF4574. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q6UW78-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDSLRKMLIS VAMLGAGAGV GYALLVIVTP GERRKQEMLK EMPLQDPRSR   50
    EEAARTQQLL LATLQEAATT QENVAWRKNW MVGGEGGAGG RSP 93
    Length:93
    Mass (Da):10,081
    Last modified:May 18, 2010 - v2
    Checksum:i7E65D81280196F93
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti89 – 891G → S in AAQ89294. (PubMed:12975309)Curated
    Sequence conflicti89 – 891G → S in AAH90057. (PubMed:15489334)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY358935 mRNA. Translation: AAQ89294.1.
    AP001458 Genomic DNA. No translation available.
    BC090057 mRNA. Translation: AAH90057.1.
    CCDSiCCDS41658.1.
    RefSeqiNP_001078841.1. NM_001085372.2.
    UniGeneiHs.569009.

    Genome annotation databases

    EnsembliENST00000377953; ENSP00000367189; ENSG00000204922.
    ENST00000531323; ENSP00000432692; ENSG00000204922.
    GeneIDi790955.
    KEGGihsa:790955.
    UCSCiuc001nui.4. human.

    Polymorphism databases

    DMDMi296434449.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY358935 mRNA. Translation: AAQ89294.1 .
    AP001458 Genomic DNA. No translation available.
    BC090057 mRNA. Translation: AAH90057.1 .
    CCDSi CCDS41658.1.
    RefSeqi NP_001078841.1. NM_001085372.2.
    UniGenei Hs.569009.

    3D structure databases

    ProteinModelPortali Q6UW78.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 612915. 6 interactions.

    PTM databases

    PhosphoSitei Q6UW78.

    Polymorphism databases

    DMDMi 296434449.

    Proteomic databases

    MaxQBi Q6UW78.
    PaxDbi Q6UW78.
    PRIDEi Q6UW78.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000377953 ; ENSP00000367189 ; ENSG00000204922 .
    ENST00000531323 ; ENSP00000432692 ; ENSG00000204922 .
    GeneIDi 790955.
    KEGGi hsa:790955.
    UCSCi uc001nui.4. human.

    Organism-specific databases

    CTDi 790955.
    GeneCardsi GC11P062439.
    H-InvDB HIX0035944.
    HGNCi HGNC:34399. C11orf83.
    HPAi HPA046851.
    neXtProti NX_Q6UW78.
    PharmGKBi PA162377760.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG82939.
    HOGENOMi HOG000111740.
    InParanoidi Q6UW78.
    OMAi KEMPEQN.
    OrthoDBi EOG7992TW.
    PhylomeDBi Q6UW78.
    TreeFami TF339744.

    Miscellaneous databases

    NextBioi 135718.

    Gene expression databases

    Bgeei Q6UW78.
    CleanExi HS_C11orf83.
    Genevestigatori Q6UW78.

    Family and domain databases

    InterProi IPR027896. DUF4574.
    [Graphical view ]
    Pfami PF15141. DUF4574. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Placenta.
    4. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z., Henzel W.J.
      Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 24-37.

    Entry informationi

    Entry nameiCK083_HUMAN
    AccessioniPrimary (citable) accession number: Q6UW78
    Secondary accession number(s): Q5FVD5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 23, 2004
    Last sequence update: May 18, 2010
    Last modified: October 1, 2014
    This is version 75 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 11
      Human chromosome 11: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families
    3. Uncharacterized protein families (UPF)
      List of uncharacterized protein family (UPF) entries

    External Data

    Dasty 3