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Q6UW78 (CK083_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UPF0723 protein C11orf83
Gene names
Name:C11orf83
ORF Names:UNQ655/PRO1286
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length93 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Secreted Probable.

Sequence similarities

Belongs to the UPF0723 family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Technical termComplete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Ref.4
Chain24 – 9370UPF0723 protein C11orf83
PRO_0000022611

Experimental info

Sequence conflict891G → S in AAQ89294. Ref.1
Sequence conflict891G → S in AAH90057. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q6UW78 [UniParc].

Last modified May 18, 2010. Version 2.
Checksum: 7E65D81280196F93

FASTA9310,081
        10         20         30         40         50         60 
MDSLRKMLIS VAMLGAGAGV GYALLVIVTP GERRKQEMLK EMPLQDPRSR EEAARTQQLL 

        70         80         90 
LATLQEAATT QENVAWRKNW MVGGEGGAGG RSP 

« Hide

References

« Hide 'large scale' references
[1]"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. expand/collapse author list , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. expand/collapse author list , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y.
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Placenta.
[4]"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z., Henzel W.J.
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 24-37.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY358935 mRNA. Translation: AAQ89294.1.
AP001458 Genomic DNA. No translation available.
BC090057 mRNA. Translation: AAH90057.1.
CCDSCCDS41658.1.
RefSeqNP_001078841.1. NM_001085372.2.
UniGeneHs.569009.

3D structure databases

ProteinModelPortalQ6UW78.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid612915. 6 interactions.

PTM databases

PhosphoSiteQ6UW78.

Polymorphism databases

DMDM296434449.

Proteomic databases

MaxQBQ6UW78.
PaxDbQ6UW78.
PRIDEQ6UW78.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000377953; ENSP00000367189; ENSG00000204922.
ENST00000531323; ENSP00000432692; ENSG00000204922.
GeneID790955.
KEGGhsa:790955.
UCSCuc001nui.4. human.

Organism-specific databases

CTD790955.
GeneCardsGC11P062439.
H-InvDBHIX0035944.
HGNCHGNC:34399. C11orf83.
HPAHPA046851.
neXtProtNX_Q6UW78.
PharmGKBPA162377760.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG82939.
HOGENOMHOG000111740.
InParanoidQ6UW78.
OMAKEMPEQN.
OrthoDBEOG7992TW.
PhylomeDBQ6UW78.
TreeFamTF339744.

Gene expression databases

BgeeQ6UW78.
CleanExHS_C11orf83.
GenevestigatorQ6UW78.

Family and domain databases

InterProIPR027896. DUF4574.
[Graphical view]
PfamPF15141. DUF4574. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio135718.

Entry information

Entry nameCK083_HUMAN
AccessionPrimary (citable) accession number: Q6UW78
Secondary accession number(s): Q5FVD5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: May 18, 2010
Last modified: July 9, 2014
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM