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Q6UW78

- CK083_HUMAN

UniProt

Q6UW78 - CK083_HUMAN

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Protein

UPF0723 protein C11orf83

Gene

C11orf83

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0723 protein C11orf83
Gene namesi
ORF Names:UNQ655/PRO1286
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:34399. C11orf83.

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162377760.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 23231 PublicationAdd
BLAST
Chaini24 – 9370UPF0723 protein C11orf83PRO_0000022611Add
BLAST

Proteomic databases

MaxQBiQ6UW78.
PaxDbiQ6UW78.
PRIDEiQ6UW78.

PTM databases

PhosphoSiteiQ6UW78.

Expressioni

Gene expression databases

BgeeiQ6UW78.
CleanExiHS_C11orf83.
GenevestigatoriQ6UW78.

Organism-specific databases

HPAiHPA046851.

Interactioni

Protein-protein interaction databases

BioGridi612915. 6 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ6UW78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0723 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG82939.
GeneTreeiENSGT00390000001930.
HOGENOMiHOG000111740.
InParanoidiQ6UW78.
OMAiKEMPEQN.
OrthoDBiEOG7992TW.
PhylomeDBiQ6UW78.
TreeFamiTF339744.

Family and domain databases

InterProiIPR027896. DUF4574.
[Graphical view]
PfamiPF15141. DUF4574. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6UW78-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDSLRKMLIS VAMLGAGAGV GYALLVIVTP GERRKQEMLK EMPLQDPRSR
60 70 80 90
EEAARTQQLL LATLQEAATT QENVAWRKNW MVGGEGGAGG RSP
Length:93
Mass (Da):10,081
Last modified:May 18, 2010 - v2
Checksum:i7E65D81280196F93
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti89 – 891G → S in AAQ89294. (PubMed:12975309)Curated
Sequence conflicti89 – 891G → S in AAH90057. (PubMed:15489334)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY358935 mRNA. Translation: AAQ89294.1.
AP001458 Genomic DNA. No translation available.
BC090057 mRNA. Translation: AAH90057.1.
CCDSiCCDS41658.1.
RefSeqiNP_001078841.1. NM_001085372.2.
UniGeneiHs.569009.

Genome annotation databases

EnsembliENST00000377953; ENSP00000367189; ENSG00000204922.
ENST00000531323; ENSP00000432692; ENSG00000204922.
GeneIDi790955.
KEGGihsa:790955.
UCSCiuc001nui.4. human.

Polymorphism databases

DMDMi296434449.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY358935 mRNA. Translation: AAQ89294.1 .
AP001458 Genomic DNA. No translation available.
BC090057 mRNA. Translation: AAH90057.1 .
CCDSi CCDS41658.1.
RefSeqi NP_001078841.1. NM_001085372.2.
UniGenei Hs.569009.

3D structure databases

ProteinModelPortali Q6UW78.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 612915. 6 interactions.

PTM databases

PhosphoSitei Q6UW78.

Polymorphism databases

DMDMi 296434449.

Proteomic databases

MaxQBi Q6UW78.
PaxDbi Q6UW78.
PRIDEi Q6UW78.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000377953 ; ENSP00000367189 ; ENSG00000204922 .
ENST00000531323 ; ENSP00000432692 ; ENSG00000204922 .
GeneIDi 790955.
KEGGi hsa:790955.
UCSCi uc001nui.4. human.

Organism-specific databases

CTDi 790955.
GeneCardsi GC11P062443.
H-InvDB HIX0035944.
HGNCi HGNC:34399. C11orf83.
HPAi HPA046851.
neXtProti NX_Q6UW78.
PharmGKBi PA162377760.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG82939.
GeneTreei ENSGT00390000001930.
HOGENOMi HOG000111740.
InParanoidi Q6UW78.
OMAi KEMPEQN.
OrthoDBi EOG7992TW.
PhylomeDBi Q6UW78.
TreeFami TF339744.

Miscellaneous databases

GenomeRNAii 790955.
NextBioi 135718.

Gene expression databases

Bgeei Q6UW78.
CleanExi HS_C11orf83.
Genevestigatori Q6UW78.

Family and domain databases

InterProi IPR027896. DUF4574.
[Graphical view ]
Pfami PF15141. DUF4574. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Placenta.
  4. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
    Zhang Z., Henzel W.J.
    Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 24-37.

Entry informationi

Entry nameiCK083_HUMAN
AccessioniPrimary (citable) accession number: Q6UW78
Secondary accession number(s): Q5FVD5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: May 18, 2010
Last modified: October 29, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3