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Q6UVH2

- Q6UVH2_HUMAN

UniProt

Q6UVH2 - Q6UVH2_HUMAN

Protein
Submitted name:

ATGR2

Gene

ATGR2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. angiotensin type II receptor activity Source: Ensembl
    2. peptide hormone binding Source: Ensembl

    GO - Biological processi

    1. aldosterone secretion Source: Ensembl
    2. behavior Source: Ensembl
    3. brain renin-angiotensin system Source: Ensembl
    4. cell growth involved in cardiac muscle cell development Source: Ensembl
    5. cellular response to dexamethasone stimulus Source: Ensembl
    6. cellular sodium ion homeostasis Source: Ensembl
    7. cerebellar cortex development Source: Ensembl
    8. dopamine biosynthetic process Source: Ensembl
    9. G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger Source: Ensembl
    10. inflammatory response Source: Ensembl
    11. negative regulation of fibroblast proliferation Source: Ensembl
    12. negative regulation of heart rate Source: Ensembl
    13. negative regulation of icosanoid secretion Source: Ensembl
    14. negative regulation of norepinephrine secretion Source: Ensembl
    15. positive regulation of branching involved in ureteric bud morphogenesis Source: Ensembl
    16. positive regulation of cell proliferation Source: Ensembl
    17. positive regulation of cytokine secretion Source: Ensembl
    18. positive regulation of metanephric glomerulus development Source: Ensembl
    19. positive regulation of nitric-oxide synthase activity Source: Ensembl
    20. positive regulation of renal sodium excretion Source: Ensembl
    21. positive regulation of transcription, DNA-templated Source: Ensembl
    22. positive regulation of vasodilation Source: Ensembl
    23. regulation of apoptotic process Source: InterPro
    24. regulation of metanephros size Source: Ensembl
    25. regulation of systemic arterial blood pressure by circulatory renin-angiotensin Source: Ensembl
    26. regulation of transcription factor import into nucleus Source: Ensembl
    27. renin-angiotensin regulation of aldosterone production Source: Ensembl
    28. response to organonitrogen compound Source: Ensembl
    29. vasodilation by angiotensin involved in regulation of systemic arterial blood pressure Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ATGR2Imported
    Gene namesi
    Name:ATGR2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: InterPro
    2. perinuclear region of cytoplasm Source: Ensembl
    3. plasma membrane Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ6UVH2.
    BgeeiQ6UVH2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6UVH2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000147. ATII_AT2_rcpt.
    IPR000248. ATII_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00241. ANGIOTENSINR.
    PR00636. ANGIOTENSN2R.
    PR00237. GPCRRHODOPSN.
    PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q6UVH2-1 [UniParc]FASTAAdd to Basket

    « Hide

    YQSVIYPFLS QRRNPWQASY IVPLVWCMAC LSSLPTFYFR DVRTIEYLGV    50
    NACIMAFPPE KYAQWSAGIA LMKNILGFII PLIFIATCYF GIRKHLLKTN 100
    SYGKNRITRD QVLKMAAAVV LAFIICWLPF HVLTFLDALA WMGVINSC 148
    Length:148
    Mass (Da):16,983
    Last modified:July 5, 2004 - v1
    Checksum:i76DA6142BE8E014B
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei148 – 1481Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AH013177 Genomic DNA. Translation: AAQ62073.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AH013177 Genomic DNA. Translation: AAQ62073.1 .

    3D structure databases

    ProteinModelPortali Q6UVH2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Gene expression databases

    ArrayExpressi Q6UVH2.
    Bgeei Q6UVH2.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000147. ATII_AT2_rcpt.
    IPR000248. ATII_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00241. ANGIOTENSINR.
    PR00636. ANGIOTENSN2R.
    PR00237. GPCRRHODOPSN.
    PROSITEi PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Partial sequence of the AGTR2 gene in Cantonese."
      Zhang M., Wang B., Zhao Y.
      Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ6UVH2_HUMAN
    AccessioniPrimary (citable) accession number: Q6UVH2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.