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Q6UVH2

- Q6UVH2_HUMAN

UniProt

Q6UVH2 - Q6UVH2_HUMAN

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Protein
Submitted name: ATGR2
Gene
ATGR2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. angiotensin type II receptor activity Source: Ensembl
  2. peptide hormone binding Source: Ensembl

GO - Biological processi

  1. G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger Source: Ensembl
  2. aldosterone secretion Source: Ensembl
  3. behavior Source: Ensembl
  4. brain renin-angiotensin system Source: Ensembl
  5. cell growth involved in cardiac muscle cell development Source: Ensembl
  6. cellular response to dexamethasone stimulus Source: Ensembl
  7. cellular sodium ion homeostasis Source: Ensembl
  8. cerebellar cortex development Source: Ensembl
  9. dopamine biosynthetic process Source: Ensembl
  10. inflammatory response Source: Ensembl
  11. negative regulation of fibroblast proliferation Source: Ensembl
  12. negative regulation of heart rate Source: Ensembl
  13. negative regulation of icosanoid secretion Source: Ensembl
  14. negative regulation of norepinephrine secretion Source: Ensembl
  15. positive regulation of branching involved in ureteric bud morphogenesis Source: Ensembl
  16. positive regulation of cell proliferation Source: Ensembl
  17. positive regulation of cytokine secretion Source: Ensembl
  18. positive regulation of metanephric glomerulus development Source: Ensembl
  19. positive regulation of nitric-oxide synthase activity Source: Ensembl
  20. positive regulation of renal sodium excretion Source: Ensembl
  21. positive regulation of transcription, DNA-templated Source: Ensembl
  22. positive regulation of vasodilation Source: Ensembl
  23. regulation of apoptotic process Source: InterPro
  24. regulation of metanephros size Source: Ensembl
  25. regulation of systemic arterial blood pressure by circulatory renin-angiotensin Source: Ensembl
  26. regulation of transcription factor import into nucleus Source: Ensembl
  27. renin-angiotensin regulation of aldosterone production Source: Ensembl
  28. response to organonitrogen compound Source: Ensembl
  29. vasodilation by angiotensin involved in regulation of systemic arterial blood pressure Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ATGR2Imported
Gene namesi
Name:ATGR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
  2. perinuclear region of cytoplasm Source: Ensembl
  3. plasma membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ6UVH2.
BgeeiQ6UVH2.

Structurei

3D structure databases

ProteinModelPortaliQ6UVH2.

Family & Domainsi

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000147. ATII_AT2_rcpt.
IPR000248. ATII_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00241. ANGIOTENSINR.
PR00636. ANGIOTENSN2R.
PR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6UVH2-1 [UniParc]FASTAAdd to Basket

« Hide

YQSVIYPFLS QRRNPWQASY IVPLVWCMAC LSSLPTFYFR DVRTIEYLGV    50
NACIMAFPPE KYAQWSAGIA LMKNILGFII PLIFIATCYF GIRKHLLKTN 100
SYGKNRITRD QVLKMAAAVV LAFIICWLPF HVLTFLDALA WMGVINSC 148
Length:148
Mass (Da):16,983
Last modified:July 5, 2004 - v1
Checksum:i76DA6142BE8E014B
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei148 – 1481Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AH013177 Genomic DNA. Translation: AAQ62073.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AH013177 Genomic DNA. Translation: AAQ62073.1 .

3D structure databases

ProteinModelPortali Q6UVH2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

ArrayExpressi Q6UVH2.
Bgeei Q6UVH2.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000147. ATII_AT2_rcpt.
IPR000248. ATII_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00241. ANGIOTENSINR.
PR00636. ANGIOTENSN2R.
PR00237. GPCRRHODOPSN.
PROSITEi PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Partial sequence of the AGTR2 gene in Cantonese."
    Zhang M., Wang B., Zhao Y.
    Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6UVH2_HUMAN
AccessioniPrimary (citable) accession number: Q6UVH2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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