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Protein

Superoxide dismutase

Gene

sod2

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sod2Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-1000995. sod2.

Structurei

3D structure databases

ProteinModelPortaliQ6UTE6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 108Sod_Fe_NInterPro annotationAdd BLAST82
Domaini115 – 218Sod_Fe_CInterPro annotationAdd BLAST104

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG004451.
KOiK04564.

Family and domain databases

InterProiView protein in InterPro
IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
PfamiView protein in Pfam
PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiView protein in PROSITE
PS00088. SOD_MN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6UTE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLCRLSVCGR GRMRCVPALA YSFCKEKHTL PDLPYDYGAL QPHISAEIMQ
60 70 80 90 100
LHHSKHHATY VNNLNITEEK YAEALAKGDV TTQVSLQAAL KFNGGGHINH
110 120 130 140 150
TIFWTNLSPN GGGEPQGELL DAIKRDFGSF EKFKEKLNTV SVGVQGSGWG
160 170 180 190 200
WLGYNKDSNR LQLAACANQD PLQGTTGLIP LLGIDVWEHA YYLQYKNVRP
210 220
DYLKAIWNVI NWENVTERYQ ASKK
Length:224
Mass (Da):25,166
Last modified:July 5, 2004 - v1
Checksum:iBC89B2B91BA61323
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY362041 mRNA. Translation: AAQ63483.1.
RefSeqiNP_001083968.1. NM_001090499.1.
UniGeneiXl.23883.

Genome annotation databases

GeneIDi399216.
KEGGixla:399216.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY362041 mRNA. Translation: AAQ63483.1.
RefSeqiNP_001083968.1. NM_001090499.1.
UniGeneiXl.23883.

3D structure databases

ProteinModelPortaliQ6UTE6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi399216.
KEGGixla:399216.

Organism-specific databases

CTDi399216.
XenbaseiXB-GENE-1000995. sod2.

Phylogenomic databases

HOVERGENiHBG004451.
KOiK04564.

Family and domain databases

InterProiView protein in InterPro
IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
PfamiView protein in Pfam
PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiView protein in PROSITE
PS00088. SOD_MN. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6UTE6_XENLA
AccessioniPrimary (citable) accession number: Q6UTE6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 15, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.