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Protein

Superoxide dismutase

Gene

sod2

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi52Divalent metal cationUniRule annotation1
Metal bindingi100Divalent metal cationUniRule annotation1
Metal bindingi185Divalent metal cationUniRule annotation1
Metal bindingi189Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sod2Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-1000995 sod2

Structurei

3D structure databases

ProteinModelPortaliQ6UTE6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 108Sod_Fe_NInterPro annotationAdd BLAST82
Domaini115 – 218Sod_Fe_CInterPro annotationAdd BLAST104

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG004451
KOiK04564

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

Q6UTE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLCRLSVCGR GRMRCVPALA YSFCKEKHTL PDLPYDYGAL QPHISAEIMQ
60 70 80 90 100
LHHSKHHATY VNNLNITEEK YAEALAKGDV TTQVSLQAAL KFNGGGHINH
110 120 130 140 150
TIFWTNLSPN GGGEPQGELL DAIKRDFGSF EKFKEKLNTV SVGVQGSGWG
160 170 180 190 200
WLGYNKDSNR LQLAACANQD PLQGTTGLIP LLGIDVWEHA YYLQYKNVRP
210 220
DYLKAIWNVI NWENVTERYQ ASKK
Length:224
Mass (Da):25,166
Last modified:July 5, 2004 - v1
Checksum:iBC89B2B91BA61323
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY362041 mRNA Translation: AAQ63483.1
RefSeqiNP_001083968.1, NM_001090499.1
UniGeneiXl.23883

Genome annotation databases

GeneIDi399216
KEGGixla:399216

Similar proteinsi

Entry informationi

Entry nameiQ6UTE6_XENLA
AccessioniPrimary (citable) accession number: Q6UTE6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health