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Protein

Superoxide dismutase

Gene

sod2

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sod2Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-1000995. sod2.

Structurei

3D structure databases

ProteinModelPortaliQ6UTE6.
SMRiQ6UTE6. Positions 27-224.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG004451.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6UTE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLCRLSVCGR GRMRCVPALA YSFCKEKHTL PDLPYDYGAL QPHISAEIMQ
60 70 80 90 100
LHHSKHHATY VNNLNITEEK YAEALAKGDV TTQVSLQAAL KFNGGGHINH
110 120 130 140 150
TIFWTNLSPN GGGEPQGELL DAIKRDFGSF EKFKEKLNTV SVGVQGSGWG
160 170 180 190 200
WLGYNKDSNR LQLAACANQD PLQGTTGLIP LLGIDVWEHA YYLQYKNVRP
210 220
DYLKAIWNVI NWENVTERYQ ASKK
Length:224
Mass (Da):25,166
Last modified:July 5, 2004 - v1
Checksum:iBC89B2B91BA61323
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY362041 mRNA. Translation: AAQ63483.1.
RefSeqiNP_001083968.1. NM_001090499.1.
UniGeneiXl.23883.

Genome annotation databases

GeneIDi399216.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY362041 mRNA. Translation: AAQ63483.1.
RefSeqiNP_001083968.1. NM_001090499.1.
UniGeneiXl.23883.

3D structure databases

ProteinModelPortaliQ6UTE6.
SMRiQ6UTE6. Positions 27-224.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi399216.

Organism-specific databases

CTDi6648.
XenbaseiXB-GENE-1000995. sod2.

Phylogenomic databases

HOVERGENiHBG004451.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "ANTICLUSTAL: multiple sequence alignment by antipole clustering and linear approximate 1-median computation."
    Di Pietro C., Di Pietro V., Emmanuele G., Ferro A., Maugeri T., Modica E., Pigola G., Pulvirenti A., Purrello M., Ragusa M., Scalia M., Shasha D., Travali S., Zimmitti V.
    (In) IEEE COMPUTER SOCIETY BIOINFORMATICS CONFERENCE, pp.0-0, Unknown Publisher (2003)
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "In vitro and in silico cloning of Xenopus laevis SOD2 cDNA and its phylogenetic analysis."
    Purrello M., Di Pietro C., Ragusa M., Pulvirenti A., Giugno R., Pietro V.D., Emmanuele G., Travali S., Scalia M., Shasha D., Ferro A.
    DNA Cell Biol. 24:111-116(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6UTE6_XENLA
AccessioniPrimary (citable) accession number: Q6UTE6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 27, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.