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Q6UGN0 (GPD_HYPAT) Reviewed, UniProtKB/Swiss-Prot

Last modified March 6, 2013. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]
EC=1.1.1.8
Gene names
Name:gld1
OrganismHypocrea atroviridis (Trichoderma atroviride)
Taxonomic identifier63577 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Hypocreomycetidae › Hypocreales › Hypocreaceae › Hypocrea › mitosporic Hypocrea › Trichoderma

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Sequence similarities

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 427427Glycerol-3-phosphate dehydrogenase [NAD(+)]
PRO_0000138097

Regions

Nucleotide binding17 – 226NAD By similarity
Region344 – 3452Substrate binding By similarity

Sites

Active site2781Proton acceptor By similarity
Binding site1201NAD By similarity
Binding site1431NAD; via amide nitrogen By similarity
Binding site1431Substrate By similarity
Binding site1761NAD; via amide nitrogen By similarity
Binding site3441NAD By similarity
Binding site3731NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6UGN0 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: AF84DC639B08C90F

FASTA42746,351
        10         20         30         40         50         60 
MAFLGGYEKK HKVTIVGSGN WGSTIAKIVA ENTRANKDVF EEDVQMWVFE EDVTIAKDSK 

        70         80         90        100        110        120 
HYDESIGDAP QKLTHVINKY HENVKYLPGI TLPSNIIANP SLVDAVQDSS ILIFNLPHQF 

       130        140        150        160        170        180 
IRNVCNQIRG KILPFARGIS CIKGVNVSDD GVSLFSEWIG DGLSIYVGAL SGANIASEIA 

       190        200        210        220        230        240 
AEKWSETTIA YDPPPMDNSR APTPRSQSPG LTMTVTEPPA DMQHRDARGR KSKTKLTPVP 

       250        260        270        280        290        300 
AEYPPLDHAC FHSLFHRPYF HVEMVSDVAG VSLGGALKNI VALAAGFVDG RGWGDNAKAA 

       310        320        330        340        350        360 
VMRIGLMEMV KFGKEFFGET VHTATFTESS AGVADLITSC SGGRNFRCAR KAVEKGITVD 

       370        380        390        400        410        420 
EVEKQDLNGQ KLQGTSTAFE VNSFLTARGL EKDYPLLTAV NAILLGKASV DDIPSLVSDT 


ERKQPLP

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References

[1]"The fungal STRE-element-binding protein Seb1 is involved but not essential for glycerol dehydrogenase (gld1) gene expression and glycerol accumulation in Trichoderma atroviride during osmotic stress."
Seidl V., Seiboth B., Karaffa L., Kubicek C.P.
Fungal Genet. Biol. 41:1132-1140(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: P1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY370658 Genomic DNA. Translation: AAR14209.1.

3D structure databases

ProteinModelPortalQ6UGN0.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 2 hits.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11728. PTHR11728. 1 hit.
PfamPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PRINTSPR00077. GPDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGPD_HYPAT
AccessionPrimary (citable) accession number: Q6UGN0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: July 5, 2004
Last modified: March 6, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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