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Q6UDJ1 (RIR2_PSHV1) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase small chain

EC=1.17.4.1
Alternative name(s):
Ribonucleotide reductase small subunit
Gene names
Name:UL40
OrganismPsittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) (Pacheco's disease virus) [Reference proteome]
Taxonomic identifier670426 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeIltovirus
Virus hostAmazona oratrix (yellow-headed parrot) [TaxID: 152276]

Protein attributes

Sequence length313 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity.

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.

Cofactor

Binds 2 iron ions per subunit By similarity.

Pathway

Genetic information processing; DNA replication.

Subunit structure

Heterodimer of a large and a small chain By similarity.

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase small chain family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 313313Ribonucleoside-diphosphate reductase small chain
PRO_0000406808

Sites

Active site1051 By similarity
Metal binding681Iron 1 By similarity
Metal binding981Iron 1 By similarity
Metal binding981Iron 2 By similarity
Metal binding1011Iron 1 By similarity
Metal binding1631Iron 2 By similarity
Metal binding1971Iron 2 By similarity
Metal binding2001Iron 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6UDJ1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 56F6F5771B40648D

FASTA31336,261
        10         20         30         40         50         60 
MSATEFLASE YYYTGECPDM RELRDLSIAN NWNEFELCYA RDEKDVDCLT EDECDFYKFV 

        70         80         90        100        110        120 
FCFLAAADDL VNVNLDNLVT LFPQKDIQHY YAEQIRIETV HSRTYSAVQL VFFRNDAIAR 

       130        140        150        160        170        180 
DRYVLEAVKD GAIRRKIDWL SRIQNEGDEL TLPEKYILMI LIEGIFFVSS FAAISYLRRH 

       190        200        210        220        230        240 
SIFQVTCQSN DLISRDETIH TTASCCIYNN WLKGHPKPSV KRIHQLFKEA VEIECDFLVA 

       250        260        270        280        290        300 
RAPKAARLID IDAIQSFVRF TANRWLSMIG VPTIYDDPAP DPTFPLALMS LEKNVNFFEH 

       310 
RSTAYSGNLV NDL 

« Hide

References

[1]"Psittacid herpesvirus 1 and infectious laryngotracheitis virus: Comparative genome sequence analysis of two avian alphaherpesviruses."
Thureen D.R., Keeler C.L. Jr.
J. Virol. 80:7863-7872(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY372243 Genomic DNA. Translation: AAQ73719.1.
RefSeqNP_944413.1. NC_005264.1.

3D structure databases

ProteinModelPortalQ6UDJ1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2657018.

Phylogenomic databases

ProtClustDBCLSP2509600.

Enzyme and pathway databases

UniPathwayUPA00326.

Family and domain databases

Gene3D1.10.620.20. 1 hit.
InterProIPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR000358. RNR_small.
[Graphical view]
PANTHERPTHR23409. PTHR23409. 1 hit.
PfamPF00268. Ribonuc_red_sm. 1 hit.
[Graphical view]
SUPFAMSSF47240. SSF47240. 1 hit.
PROSITEPS00368. RIBORED_SMALL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRIR2_PSHV1
AccessionPrimary (citable) accession number: Q6UDJ1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: July 5, 2004
Last modified: December 11, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways