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Q6U841

- S4A10_HUMAN

UniProt

Q6U841 - S4A10_HUMAN

Protein

Sodium-driven chloride bicarbonate exchanger

Gene

SLC4A10

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Electrogenic sodium/bicarbonate cotransporter in exchange for intracellular chloride. Plays an important role in regulating intracellular pH By similarity.By similarity

    GO - Molecular functioni

    1. inorganic anion exchanger activity Source: InterPro
    2. symporter activity Source: UniProtKB-KW

    GO - Biological processi

    1. bicarbonate transport Source: UniProtKB
    2. chloride transport Source: UniProtKB
    3. ion transport Source: Reactome
    4. regulation of pH Source: Ensembl
    5. sodium ion transport Source: UniProtKB-KW
    6. transmembrane transport Source: Reactome

    Keywords - Biological processi

    Antiport, Ion transport, Sodium transport, Symport, Transport

    Keywords - Ligandi

    Sodium

    Enzyme and pathway databases

    ReactomeiREACT_19298. Bicarbonate transporters.

    Protein family/group databases

    TCDBi2.A.31.2.14. the anion exchanger (ae) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sodium-driven chloride bicarbonate exchanger
    Alternative name(s):
    Solute carrier family 4 member 10
    Gene namesi
    Name:SLC4A10
    Synonyms:NCBE
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:13811. SLC4A10.

    Subcellular locationi

    Cell membrane; Multi-pass membrane protein
    Note: Localizes to the basolateral membrane.By similarity

    GO - Cellular componenti

    1. basolateral plasma membrane Source: Ensembl
    2. integral component of membrane Source: UniProtKB
    3. plasma membrane Source: Reactome

    Keywords - Cellular componenti

    Cell membrane, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA37810.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 11181118Sodium-driven chloride bicarbonate exchangerPRO_0000245240Add
    BLAST

    Proteomic databases

    MaxQBiQ6U841.
    PaxDbiQ6U841.
    PRIDEiQ6U841.

    PTM databases

    PhosphoSiteiQ6U841.

    Expressioni

    Gene expression databases

    BgeeiQ6U841.
    CleanExiHS_SLC4A10.
    GenevestigatoriQ6U841.

    Organism-specific databases

    HPAiHPA034755.

    Interactioni

    Protein-protein interaction databases

    BioGridi121475. 1 interaction.
    IntActiQ6U841. 2 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6U841.
    SMRiQ6U841. Positions 117-429, 493-533.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 509509CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini531 – 5388ExtracellularSequence Analysis
    Topological domaini560 – 5623CytoplasmicSequence Analysis
    Topological domaini584 – 59613ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini618 – 6269CytoplasmicSequence Analysis
    Topological domaini648 – 72073ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini742 – 76221CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini784 – 80926ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini831 – 85525CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini877 – 91236ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini934 – 9352CytoplasmicSequence Analysis
    Topological domaini957 – 99842ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini1020 – 111899CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei510 – 53021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei539 – 55921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei563 – 58321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei597 – 61721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei627 – 64721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei721 – 74121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei763 – 78321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei810 – 83021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei856 – 87621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei913 – 93321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei936 – 95621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei999 – 101921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG268067.
    HOGENOMiHOG000280684.
    HOVERGENiHBG004326.
    InParanoidiQ6U841.
    KOiK13861.
    OMAiNTHANDP.
    OrthoDBiEOG7TMZR0.
    PhylomeDBiQ6U841.
    TreeFamiTF313630.

    Family and domain databases

    Gene3Di3.40.1100.10. 2 hits.
    InterProiIPR013769. Band3_cytoplasmic_dom.
    IPR011531. HCO3_transpt_C.
    IPR003020. HCO3_transpt_euk.
    IPR003024. Na/HCO3_transpt.
    IPR016152. PTrfase/Anion_transptr.
    [Graphical view]
    PANTHERiPTHR11453. PTHR11453. 1 hit.
    PfamiPF07565. Band_3_cyto. 1 hit.
    PF00955. HCO3_cotransp. 1 hit.
    [Graphical view]
    PRINTSiPR01231. HCO3TRNSPORT.
    PR01232. NAHCO3TRSPRT.
    SUPFAMiSSF55804. SSF55804. 2 hits.
    TIGRFAMsiTIGR00834. ae. 1 hit.

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q6U841-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MEIKDQGAQM EPLLPTRNDE EAVVDRGGTR SILKTHFEKE DLEGHRTLFI     50
    GVHVPLGGRK SHRRHRHRGH KHRKRDRERD SGLEDGRESP SFDTPSQRVQ 100
    FILGTEDDDE EHIPHDLFTE LDEICWREGE DAEWRETARW LKFEEDVEDG 150
    GERWSKPYVA TLSLHSLFEL RSCILNGTVL LDMHANTLEE IADMVLDQQV 200
    SSGQLNEDVR HRVHEALMKQ HHHQNQKKLT NRIPIVRSFA DIGKKQSEPN 250
    SMDKNAGQVV SPQSAPACVE NKNDVSRENS TVDFSKGLGG QQKGHTSPCG 300
    MKQRHEKGPP HQQEREVDLH FMKKIPPGAE ASNILVGELE FLDRTVVAFV 350
    RLSPAVLLQG LAEVPIPTRF LFILLGPLGK GQQYHEIGRS IATLMTDEVF 400
    HDVAYKAKDR NDLVSGIDEF LDQVTVLPPG EWDPSIRIEP PKNVPSQEKR 450
    KIPAVPNGTA AHGEAEPHGG HSGPELQRTG RIFGGLILDI KRKAPYFWSD 500
    FRDAFSLQCL ASFLFLYCAC MSPVITFGGL LGEATEGRIS AIESLFGASM 550
    TGIAYSLFGG QPLTILGSTG PVLVFEKILF KFCKEYGLSY LSLRASIGLW 600
    TATLCIILVA TDASSLVCYI TRFTEEAFAS LICIIFIYEA LEKLFELSEA 650
    YPINMHNDLE LLTQYSCNCV EPHNPSNGTL KEWRESNISA SDIIWENLTV 700
    SECKSLHGEY VGRACGHDHP YVPDVLFWSV ILFFSTVTLS ATLKQFKTSR 750
    YFPTKVRSIV SDFAVFLTIL CMVLIDYAIG IPSPKLQVPS VFKPTRDDRG 800
    WFVTPLGPNP WWTVIAAIIP ALLCTILIFM DQQITAVIIN RKEHKLKKGC 850
    GYHLDLLMVA VMLGVCSIMG LPWFVAATVL SITHVNSLKL ESECSAPGEQ 900
    PKFLGIREQR VTGLMIFILM GSSVFMTSIL KFIPMPVLYG VFLYMGASSL 950
    KGIQFFDRIK LFWMPAKHQP DFIYLRHVPL RKVHLFTIIQ MSCLGLLWII 1000
    KVSRAAIVFP MMVLALVFVR KLMDLLFTKR ELSWLDDLMP ESKKKKLEDA 1050
    EKEEEQSMLA MEDEGTVQLP LEGHYRDDPS VINISDEMSK TALWRNLLIT 1100
    ADNSKDKESS FPSKSSPS 1118
    Length:1,118
    Mass (Da):125,946
    Last modified:July 5, 2004 - v1
    Checksum:i2376529C2CBE04E2
    GO
    Isoform 2 (identifier: Q6U841-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         287-316: Missing.

    Show »
    Length:1,088
    Mass (Da):122,641
    Checksum:i900D304004CC7208
    GO
    Isoform 3 (identifier: Q6U841-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-16: MEIKDQGAQMEPLLPT → MQSLGVSGNRKVMQSGTCEPFQSLSHQ
         287-316: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:1,099
    Mass (Da):123,777
    Checksum:iB3A73B8131408E8E
    GO
    Isoform 4 (identifier: Q6U841-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         370-408: FLFILLGPLG...VFHDVAYKAK → YFMMLPIKLK...LLENGIQAFE
         409-1118: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:408
    Mass (Da):46,839
    Checksum:i1C70E5B511C6A6CE
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti336 – 3361V → L in BAB18301. (PubMed:10993873)Curated
    Sequence conflicti699 – 6991T → I in BAH11596. (PubMed:14702039)Curated
    Sequence conflicti1008 – 10081V → A in BAH11596. (PubMed:14702039)Curated
    Sequence conflicti1009 – 10091F → S in BAB18301. (PubMed:10993873)Curated
    Sequence conflicti1015 – 10151A → S in BAB18301. (PubMed:10993873)Curated
    Sequence conflicti1033 – 10331S → C in BAB18301. (PubMed:10993873)Curated
    Sequence conflicti1048 – 10481E → G in BAH11596. (PubMed:14702039)Curated
    Sequence conflicti1049 – 10491D → Y in BAB18301. (PubMed:10993873)Curated
    Sequence conflicti1057 – 10582SM → CV in BAB18301. (PubMed:10993873)Curated
    Sequence conflicti1060 – 10601A → P in BAB18301. (PubMed:10993873)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 1616MEIKD…PLLPT → MQSLGVSGNRKVMQSGTCEP FQSLSHQ in isoform 3. 1 PublicationVSP_044993Add
    BLAST
    Alternative sequencei287 – 31630Missing in isoform 2 and isoform 3. 3 PublicationsVSP_019653Add
    BLAST
    Alternative sequencei370 – 40839FLFIL…AYKAK → YFMMLPIKLKIVMTWYQELM SFWIRLLFSLLENGIQAFE in isoform 4. 1 PublicationVSP_054471Add
    BLAST
    Alternative sequencei409 – 1118710Missing in isoform 4. 1 PublicationVSP_054472Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB040457 mRNA. Translation: BAB18301.1.
    AY376402 mRNA. Translation: AAQ83632.1.
    AK293793 mRNA. Translation: BAH11596.1.
    AK294767 mRNA. Translation: BAH11876.1.
    AC008063 Genomic DNA. No translation available.
    AC062022 Genomic DNA. No translation available.
    AC092841 Genomic DNA. No translation available.
    AC009487 Genomic DNA. No translation available.
    AC092654 Genomic DNA. No translation available.
    AC096654 Genomic DNA. Translation: AAX88962.1.
    CH471058 Genomic DNA. Translation: EAX11364.1.
    BC136269 mRNA. Translation: AAI36270.1.
    BC143714 mRNA. Translation: AAI43715.1.
    AL713680 mRNA. Translation: CAD28484.1.
    AL832525 mRNA. Translation: CAD38630.1.
    CCDSiCCDS46438.1. [Q6U841-2]
    CCDS54411.1. [Q6U841-1]
    CCDS54412.1. [Q6U841-3]
    RefSeqiNP_001171486.1. NM_001178015.1. [Q6U841-1]
    NP_001171487.1. NM_001178016.1. [Q6U841-3]
    NP_071341.2. NM_022058.3. [Q6U841-2]
    UniGeneiHs.333958.

    Genome annotation databases

    EnsembliENST00000375514; ENSP00000364664; ENSG00000144290. [Q6U841-3]
    ENST00000415876; ENSP00000395797; ENSG00000144290. [Q6U841-2]
    ENST00000446997; ENSP00000393066; ENSG00000144290. [Q6U841-1]
    GeneIDi57282.
    KEGGihsa:57282.
    UCSCiuc002ubx.4. human. [Q6U841-1]
    uc002uby.4. human. [Q6U841-2]

    Polymorphism databases

    DMDMi74710237.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB040457 mRNA. Translation: BAB18301.1 .
    AY376402 mRNA. Translation: AAQ83632.1 .
    AK293793 mRNA. Translation: BAH11596.1 .
    AK294767 mRNA. Translation: BAH11876.1 .
    AC008063 Genomic DNA. No translation available.
    AC062022 Genomic DNA. No translation available.
    AC092841 Genomic DNA. No translation available.
    AC009487 Genomic DNA. No translation available.
    AC092654 Genomic DNA. No translation available.
    AC096654 Genomic DNA. Translation: AAX88962.1 .
    CH471058 Genomic DNA. Translation: EAX11364.1 .
    BC136269 mRNA. Translation: AAI36270.1 .
    BC143714 mRNA. Translation: AAI43715.1 .
    AL713680 mRNA. Translation: CAD28484.1 .
    AL832525 mRNA. Translation: CAD38630.1 .
    CCDSi CCDS46438.1. [Q6U841-2 ]
    CCDS54411.1. [Q6U841-1 ]
    CCDS54412.1. [Q6U841-3 ]
    RefSeqi NP_001171486.1. NM_001178015.1. [Q6U841-1 ]
    NP_001171487.1. NM_001178016.1. [Q6U841-3 ]
    NP_071341.2. NM_022058.3. [Q6U841-2 ]
    UniGenei Hs.333958.

    3D structure databases

    ProteinModelPortali Q6U841.
    SMRi Q6U841. Positions 117-429, 493-533.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 121475. 1 interaction.
    IntActi Q6U841. 2 interactions.

    Chemistry

    DrugBanki DB01390. Sodium bicarbonate.

    Protein family/group databases

    TCDBi 2.A.31.2.14. the anion exchanger (ae) family.

    PTM databases

    PhosphoSitei Q6U841.

    Polymorphism databases

    DMDMi 74710237.

    Proteomic databases

    MaxQBi Q6U841.
    PaxDbi Q6U841.
    PRIDEi Q6U841.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000375514 ; ENSP00000364664 ; ENSG00000144290 . [Q6U841-3 ]
    ENST00000415876 ; ENSP00000395797 ; ENSG00000144290 . [Q6U841-2 ]
    ENST00000446997 ; ENSP00000393066 ; ENSG00000144290 . [Q6U841-1 ]
    GeneIDi 57282.
    KEGGi hsa:57282.
    UCSCi uc002ubx.4. human. [Q6U841-1 ]
    uc002uby.4. human. [Q6U841-2 ]

    Organism-specific databases

    CTDi 57282.
    GeneCardsi GC02P162444.
    HGNCi HGNC:13811. SLC4A10.
    HPAi HPA034755.
    MIMi 605556. gene.
    neXtProti NX_Q6U841.
    PharmGKBi PA37810.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG268067.
    HOGENOMi HOG000280684.
    HOVERGENi HBG004326.
    InParanoidi Q6U841.
    KOi K13861.
    OMAi NTHANDP.
    OrthoDBi EOG7TMZR0.
    PhylomeDBi Q6U841.
    TreeFami TF313630.

    Enzyme and pathway databases

    Reactomei REACT_19298. Bicarbonate transporters.

    Miscellaneous databases

    ChiTaRSi SLC4A10. human.
    GenomeRNAii 57282.
    NextBioi 35479014.
    PROi Q6U841.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q6U841.
    CleanExi HS_SLC4A10.
    Genevestigatori Q6U841.

    Family and domain databases

    Gene3Di 3.40.1100.10. 2 hits.
    InterProi IPR013769. Band3_cytoplasmic_dom.
    IPR011531. HCO3_transpt_C.
    IPR003020. HCO3_transpt_euk.
    IPR003024. Na/HCO3_transpt.
    IPR016152. PTrfase/Anion_transptr.
    [Graphical view ]
    PANTHERi PTHR11453. PTHR11453. 1 hit.
    Pfami PF07565. Band_3_cyto. 1 hit.
    PF00955. HCO3_cotransp. 1 hit.
    [Graphical view ]
    PRINTSi PR01231. HCO3TRNSPORT.
    PR01232. NAHCO3TRSPRT.
    SUPFAMi SSF55804. SSF55804. 2 hits.
    TIGRFAMsi TIGR00834. ae. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The Na+-driven Cl-/HCO3- exchanger. Cloning, tissue distribution, and functional characterization."
      Wang C.-Z., Yano H., Nagashima K., Seino S.
      J. Biol. Chem. 275:35486-35490(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
    2. "Cloning and functional characterisation of human kidney 'NCBE'."
      Choi I., Kobayashi C., Rojas J.R., Boron W.F.
      Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Tissue: Kidney.
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4).
      Tissue: Brain and Cerebellum.
    4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Tissue: Cerebellum and Testis.
    7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 897-1118 (ISOFORM 1).
      Tissue: Amygdala.

    Entry informationi

    Entry nameiS4A10_HUMAN
    AccessioniPrimary (citable) accession number: Q6U841
    Secondary accession number(s): B7Z1R0
    , B7Z2J0, B7ZLC5, B9EG69, F8W675, Q4ZFX6, Q8TCP2, Q9HCQ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 11, 2006
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 2
      Human chromosome 2: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3