Q6U6Z9 (Q6U6Z9_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Zinc finger transcription factor Gli3 EMBL AAQ84329.1

Gene names

Name:

gli3 ZFIN ZDB-GENE-041111-162

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAQ84329.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	1553 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	regulation of neurogenesis Inferred from genetic interaction. Source: ZFIN
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6U6Z9 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 2C9AEC3E0F890A03	FASTA	1,553	171,018
	10 20 30 40 50 60 MEPQFQTSSS TEKRMENVVG TNSAPTRTDI SEKAVASSTT SNEDDSSGSP YHLERRNTIS 70 80 90 100 110 120 AQTDVVNTSG KVSEEPSTST DERLPLVKKE LQSFLHRLAD HTLPYRGTLF AMDLRSGYLD 130 140 150 160 170 180 PHYTAPQFFR AFHHPVPIDD RHTQGRYIYE PSPVPSLHMP PALAASPTFS DISLIRISPH 190 200 210 220 230 240 RNPSMGTDSP FNPSHPYINP YMDYIRSLHS SPSLSMVSAA RGLSPADTHH TGLTTAEYYH 250 260 270 280 290 300 QMALLVGHRS PYADLIPSVG STTGPASSAL HMEYLQAMES SRFPSPRLIN RPSRKRPIPN 310 320 330 340 350 360 SPSLSDPSFD LQAMIRTSPN SLVTILNNSR SSSSNSGSYG HLSAGTISPA LSFAYPPTPV 370 380 390 400 410 420 ALQMHQQLIS RQPGIVGSAF GHSPPLMHSA LAFSTQRPVP AIQTSSLAPT ERSIVSNDSQ 430 440 450 460 470 480 SKPTSESAVS STGDPMNHKR SKLKPEEEPP SPRAVSMQEQ MNGMTLVKEE GDKEEGKQEP 490 500 510 520 530 540 EVVYETNCHW DGCCREFDTQ EQLVHHINND HIHGEKKEFV CRWEECSREQ KPFKAQYMLV 550 560 570 580 590 600 VHMRRHTGEK PHKCTFEGCS KAYSRLENLK THLRSHTGEK PYVCEHEGCN KAFSNASDRA 610 620 630 640 650 660 KHQNRTHSNE KPYVCKIPGC TKRYTDPSSL RKHVKTVHGP EAHVTKKQRG ETYPRPPPQP 670 680 690 700 710 720 REPGATTDQK EYTHATSKQD ECLQVKSIKT EKPMTSQSSP GSQSSCSSDQ SINGPHVSQG 730 740 750 760 770 780 VQLTVNSIGL AGEVAMLEDM ENEEEDEENR EGEKEDAPIM DSTVSTATSS AATIVLQTHR 790 800 810 820 830 840 SVGRPLRWME HVKMERLRQV NGAVPRLGFL PPTPPRKGQA MPALTGKGQC LGRMTSVRVP 850 860 870 880 890 900 PCPEPSNTEL TILSLLHERR DSSGSNTSSA YLSSSRRSSG ISPCFSSRCS SQASLSEYSP 910 920 930 940 950 960 HRHIHNLSAT DSYDPISTDA SRRSSEASQY DGGSSSAVVF GGSGVFKGSG MGSRGDLNLT 970 980 990 1000 1010 1020 PAQHYSLKAK YAAATGGPPP TPLPSMGHIN LKTHFALKED RKDTGQLTLP PLVRSRRCSD 1030 1040 1050 1060 1070 1080 GAHNSHDSQA VYQRKGTYFG GGPGKNDRRA SDPTHHKQNL SSYGLPQVRH FSSLNNMTSS 1090 1100 1110 1120 1130 1140 PNPASYGYSN REDHSLNLQN STCHVDSFQS GLHSPCPPSI MEQSALENIF MNQDGLLLRV 1150 1160 1170 1180 1190 1200 NENIQSDFMQ YLHSQDQESI IIQDNHRPIF NPADDQNFLS PQQQQEGVEQ EDTRIDLMPI 1210 1220 1230 1240 1250 1260 QSNEVSSASA DVTIPRQPFQ RCGRWSDQSG SVSNAFGRFG NMVVQQQPID FIDQHSALQH 1270 1280 1290 1300 1310 1320 MGGISYGCRN SEQHLQVAKP AQEKSRMKTG IKTESSSTFQ LESKHSNFGR PDFSHIFSAP 1330 1340 1350 1360 1370 1380 IHQKCSQHTV VSQSYPQQNQ ITNQDSSNLF LQRPGNCSLL LAYRPQPAVN TSYSTRQDIN 1390 1400 1410 1420 1430 1440 SHNVQSCHPQ SLNNRLGTSC SLSNQVSVVK LDQVNHLQIN SCSTIQQQKP VFIDKCFDPE 1450 1460 1470 1480 1490 1500 ESKLSHAIVQ SCLMESLMAE KERTSKVLLS SGVGQVTSKV ERSPAEKVGL GICSIGGDSY 1510 1520 1530 1540 1550 DQGSVVSSSR LSNSHDSFAF HSVDPGTNNM AISDMNSLLT TLAEESKFLA IIQ

References

[1]	"Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling." Tyurina O.V., Guner B., Popova E., Feng J., Schier A.F., Kohtz J.D., Karlstrom R.O. Dev. Biol. 277:537-556(2005) [PubMed: 15617692] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY377429 mRNA. Translation: AAQ84329.1.
IPI	IPI00503206.
RefSeq	NP_991291.1. NM_205728.1.
UniGene	Dr.99315.
3D structure databases
HSSP	HSSP built from PDB template 1ARD based on UniProtKB P07248.
ProteinModelPortal	Q6U6Z9.
SMR	Q6U6Z9. Positions 485-639.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6U6Z9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	403042.
KEGG	dre:403042.
Organism-specific databases
CTD	2737.
ZFIN	ZDB-GENE-041111-162. gli3.
Phylogenomic databases
eggNOG	fiNOG04344.
GeneTree	ENSGT00600000084058.
HOGENOM	HBG447235.
HOVERGEN	HBG005844.
InParanoid	Q6U6Z9.
Gene expression databases
ArrayExpress	Q6U6Z9.
Bgee	Q6U6Z9.
Family and domain databases
InterPro	IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. IPR013087. Znf_C2H2/integrase_DNA-bd. [Graphical view]
Gene3D	G3DSA:3.30.160.60. Znf_C2H2/integrase_DNA-bd. 4 hits.
KO	K06230.
Pfam	PF00096. zf-C2H2. 4 hits. [Graphical view]
SMART	SM00355. ZnF_C2H2. 5 hits. [Graphical view]
PROSITE	PS00028. ZINC_FINGER_C2H2_1. 4 hits. PS50157. ZINC_FINGER_C2H2_2. 4 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6U6Z9_DANRE

Accession

Primary (citable) accession number: Q6U6Z9

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	November 16, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)