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Protein
Submitted name:

C-C motif chemokine receptor 7

Gene

Ccr7

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-RNO-380108. Chemokine receptors bind chemokines.
R-RNO-418594. G alpha (i) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
C-C motif chemokine receptor 7Imported
Submitted name:
Chemokine (C-C motif) receptor 7Imported
Submitted name:
Chemokine receptor 7-like proteinImported
Gene namesi
Name:Ccr7Imported
ORF Names:rCG_34318Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi735151. Ccr7.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei59 – 84HelicalSequence analysisAdd BLAST26
Transmembranei96 – 116HelicalSequence analysisAdd BLAST21
Transmembranei122 – 150HelicalSequence analysisAdd BLAST29
Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Transmembranei221 – 249HelicalSequence analysisAdd BLAST29
Transmembranei261 – 279HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501084542925 – 378Sequence analysisAdd BLAST354

Expressioni

Gene expression databases

BgeeiENSRNOG00000010665.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000014163.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 326G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST252

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IMBE. Eukaryota.
ENOG4110ZGY. LUCA.
GeneTreeiENSGT00760000118785.
HOGENOMiHOG000234122.
HOVERGENiHBG106917.
KOiK04182.
OMAiRCCLNPF.
OrthoDBiEOG091G0BDV.
TreeFamiTF330966.

Family and domain databases

InterProiView protein in InterPro
IPR001718. Chemokine_CCR7.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00657. CCCHEMOKINER.
PR00641. CHEMOKINER7.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6U2D6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLGKPTKNV LVVALLVIFQ VCFCQDEVTD DYIGENTTVD YTLYESVCFK
60 70 80 90 100
KDVRNFKAWF LPLMYSVICF VGLLGNGLVV LTYIYFKRLK TMTDTYLLNL
110 120 130 140 150
AVADILFLMI LPFWAYSEAK SWIFGAYLCK SIFGIYKLSF FSGMLLLLCI
160 170 180 190 200
SIDRYVAIVQ AVSAHRHRAR VLLISKLSCI GIWTLAFFLS IPELLYSGLQ
210 220 230 240 250
KNSGEDTWRC SLVSAQVEAL IAIQVAQMVV GFVLPMLAMS FCYLVIIRTL
260 270 280 290 300
LQARNFERNK AIKVIIAVVV VFVVFQLPYN GVVLAQTVAN FNITNSSCEA
310 320 330 340 350
SKQLNIAYDV TYSLASVRCC VNPFLYAFIG VKFRSDLFKL FKDLGCLSQE
360 370
RLRQWSSCRH VRHTSVSMEA ETTTTFSP
Length:378
Mass (Da):42,822
Last modified:July 5, 2004 - v1
Checksum:iA015E711DC4B521F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07030450 Genomic DNA. No translation available.
BC089762 mRNA. Translation: AAH89762.1.
AY379972 mRNA. Translation: AAR24573.1.
CH473948 Genomic DNA. Translation: EDM05972.1.
RefSeqiNP_955783.1. NM_199489.4.
UniGeneiRn.229736.

Genome annotation databases

EnsembliENSRNOT00000014163; ENSRNOP00000014163; ENSRNOG00000010665.
GeneIDi287673.
KEGGirno:287673.
UCSCiRGD:735151. rat.

Similar proteinsi

Entry informationi

Entry nameiQ6U2D6_RAT
AccessioniPrimary (citable) accession number: Q6U2D6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported