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Protein
Submitted name:

C-C motif chemokine receptor 7

Gene

Ccr7

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-RNO-380108 Chemokine receptors bind chemokines
R-RNO-418594 G alpha (i) signalling events

Names & Taxonomyi

Protein namesi
Submitted name:
C-C motif chemokine receptor 7Imported
Submitted name:
Chemokine (C-C motif) receptor 7Imported
Submitted name:
Chemokine receptor 7-like proteinImported
Gene namesi
Name:Ccr7Imported
ORF Names:rCG_34318Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi735151 Ccr7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei59 – 84HelicalSequence analysisAdd BLAST26
Transmembranei96 – 116HelicalSequence analysisAdd BLAST21
Transmembranei122 – 150HelicalSequence analysisAdd BLAST29
Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Transmembranei221 – 249HelicalSequence analysisAdd BLAST29
Transmembranei261 – 279HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501431066825 – 378Sequence analysisAdd BLAST354

Expressioni

Gene expression databases

BgeeiENSRNOG00000010665

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000014163

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 326G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST252

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IMBE Eukaryota
ENOG4110ZGY LUCA
GeneTreeiENSGT00760000118785
HOGENOMiHOG000234122
HOVERGENiHBG106917
KOiK04182
OMAiRCCLNPF
OrthoDBiEOG091G0BDV
TreeFamiTF330966

Family and domain databases

InterProiView protein in InterPro
IPR001718 Chemokine_CCR7
IPR000355 Chemokine_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00657 CCCHEMOKINER
PR00641 CHEMOKINER7
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6U2D6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLGKPTKNV LVVALLVIFQ VCFCQDEVTD DYIGENTTVD YTLYESVCFK
60 70 80 90 100
KDVRNFKAWF LPLMYSVICF VGLLGNGLVV LTYIYFKRLK TMTDTYLLNL
110 120 130 140 150
AVADILFLMI LPFWAYSEAK SWIFGAYLCK SIFGIYKLSF FSGMLLLLCI
160 170 180 190 200
SIDRYVAIVQ AVSAHRHRAR VLLISKLSCI GIWTLAFFLS IPELLYSGLQ
210 220 230 240 250
KNSGEDTWRC SLVSAQVEAL IAIQVAQMVV GFVLPMLAMS FCYLVIIRTL
260 270 280 290 300
LQARNFERNK AIKVIIAVVV VFVVFQLPYN GVVLAQTVAN FNITNSSCEA
310 320 330 340 350
SKQLNIAYDV TYSLASVRCC VNPFLYAFIG VKFRSDLFKL FKDLGCLSQE
360 370
RLRQWSSCRH VRHTSVSMEA ETTTTFSP
Length:378
Mass (Da):42,822
Last modified:July 5, 2004 - v1
Checksum:iA015E711DC4B521F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07030450 Genomic DNA No translation available.
BC089762 mRNA Translation: AAH89762.1
AY379972 mRNA Translation: AAR24573.1
CH473948 Genomic DNA Translation: EDM05972.1
RefSeqiNP_955783.1, NM_199489.4
UniGeneiRn.229736

Genome annotation databases

EnsembliENSRNOT00000014163; ENSRNOP00000014163; ENSRNOG00000010665
GeneIDi287673
KEGGirno:287673
UCSCiRGD:735151 rat

Similar proteinsi

Entry informationi

Entry nameiQ6U2D6_RAT
AccessioniPrimary (citable) accession number: Q6U2D6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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