Q6TXQ4 (Q6TXQ4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: H3L-like histone EMBL AAQ96275.1
Organism	Homo sapiens (Human) EMBL AAQ96275.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	107 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

Ontologies

Keywords
Cellular component	Chromosome SAAS SAAS000164 Nucleus SAAS SAAS000164
Ligand	DNA-binding SAAS SAAS000164
Technical term	3D-structure PDB 4HCZ
Gene Ontology (GO)
Biological_process	nucleosome assembly Inferred from electronic annotation. Source: InterPro
Cellular_component	nucleosome Inferred from electronic annotation. Source: InterPro nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	22	1	N6,N6,N6-trimethyllysine PDB 4HCZ
Experimental info
	Non-terminal residue	1	1	EMBL AAQ96275.1
	Non-terminal residue	107	1	EMBL AAQ96275.1

Sequences

	Sequence		Length	Mass (Da)
	Q6TXQ4 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 10F48D9915FCE6E7	FASTA	107	12,104
	10 20 30 40 50 60 APRKQLATKA ARKSAPSTGG VKKPHRYRPG TVALREIRRY QKSTELLVRK LPFQRLVREI 70 80 90 100 AQDFKTDLRF QSAAIGALQE ASEAYLVNLF EDTNLCAIHA KRVTIMP

References

[1]	"A new family of H3 histone genes with the S.//.A.IG motif." Mancini P., Pulcrano G., Piscopo M., Aniello F., Branno M., Fucci L. Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1." Musselman C.A., Avvakumov N., Watanabe R., Abraham C.G., Lalonde M.E., Hong Z., Allen C., Roy S., Nunez J.K., Nickoloff J., Kulesza C.A., Yasui A., Cote J., Kutateladze T.G. Nat. Struct. Mol. Biol. 19:1266-1272(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 17-26, METHYLATION AT LYS-22.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AY383568 Genomic DNA. Translation: AAQ96275.1.

IPI

IPI00219038.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4HCZ	X-ray	1.85	C/D	17-26	[»]

HSSP

HSSP built from PDB template 1AOI based on UniProtKB P02302.

ProteinModelPortal

Q6TXQ4.

ModBase

Search...

Protein-protein interaction databases

STRING

Q6TXQ4.

Proteomic databases

PRIDE

Q6TXQ4.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Phylogenomic databases

HOVERGEN

HBG001172.

Gene expression databases

ArrayExpress

Q6TXQ4.

Family and domain databases

Gene3D

1.10.20.10. 1 hit.

InterPro

IPR009072. Histone-fold.
IPR007125. Histone_core_D.
IPR000164. Histone_H3.
[Graphical view]

PANTHER

PTHR11426. PTHR11426. 1 hit.

Pfam

PF00125. Histone. 1 hit.
[Graphical view]

PRINTS

PR00622. HISTONEH3.

SMART

SM00428. H3. 1 hit.
[Graphical view]

SUPFAM

SSF47113. Histone-fold. 1 hit.

PROSITE

PS00959. HISTONE_H3_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q6TXQ4_HUMAN

Accession

Primary (citable) accession number: Q6TXQ4

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.