H3L-like histone

Functionⁱ

GO - Molecular functionⁱ

DNA binding Source: UniProtKB-KW
protein heterodimerization activity Source: InterPro

Keywordsⁱ

Molecular function	DNA-bindingSAAS annotation

Molecular function

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: H3L-like histoneImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Subcellular locationⁱ

Chromosome
SAAS annotation
Automatic assertion according to rulesⁱ
- SAAS:SAAS00690744

Nucleus
SAAS annotation
Automatic assertion according to rulesⁱ
- SAAS:SAAS00690742

GO - Cellular componentⁱ

nucleosome Source: InterPro
nucleus Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

ChromosomeSAAS annotation, NucleusSAAS annotation

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q6TXQ4.
PeptideAtlas More...PeptideAtlasⁱ	Q6TXQ4.
PRIDEⁱ	Q6TXQ4.

Interactionⁱ

GO - Molecular functionⁱ

protein heterodimerization activity Source: InterPro

Complete GO annotation...

Structureⁱ

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	4HCZ	X-ray	1.85	C/D	17-26	[»]
ProteinModelPortalⁱ	Q6TXQ4.
SMRⁱ	Q6TXQ4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	2 – 107	HistoneInterPro annotationAdd BLAST		106

Sequence similaritiesⁱ

Belongs to the histone H3 family.SAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG1745. Eukaryota. COG2036. LUCA.
HOVERGENⁱ	HBG001172.

Family and domain databases

InterProⁱ	View protein in InterPro IPR009072. Histone-fold. IPR007125. Histone_H2A/H2B/H3. IPR000164. Histone_H3/CENP-A.
PANTHERⁱ	PTHR11426. PTHR11426. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00125. Histone. 1 hit.
PRINTSⁱ	PR00622. HISTONEH3.
SMARTⁱ	View protein in SMART SM00428. H3. 1 hit.
SUPFAMⁱ	SSF47113. SSF47113. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00959. HISTONE_H3_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q6TXQ4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
APRKQLATKA ARKSAPSTGG VKKPHRYRPG TVALREIRRY QKSTELLVRK 
        60         70         80         90        100
LPFQRLVREI AQDFKTDLRF QSAAIGALQE ASEAYLVNLF EDTNLCAIHA 

KRVTIMP

Length:107

Mass (Da):12,104

Last modified:July 5, 2004 - v1

Checksum:ⁱ10F48D9915FCE6E7

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1
Non-terminal residueⁱ	107	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY383568 Genomic DNA. Translation: AAQ96275.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AY383568 Genomic DNA. Translation: AAQ96275.1.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY383568 Genomic DNA. Translation: AAQ96275.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AY383568 Genomic DNA. Translation: AAQ96275.1.

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	4HCZ	X-ray	1.85	C/D	17-26	[»]
ProteinModelPortalⁱ	Q6TXQ4.
SMRⁱ	Q6TXQ4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PaxDbⁱ	Q6TXQ4.
PeptideAtlas More...PeptideAtlasⁱ	Q6TXQ4.
PRIDEⁱ	Q6TXQ4.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Phylogenomic databases

eggNOGⁱ	KOG1745. Eukaryota. COG2036. LUCA.
HOVERGENⁱ	HBG001172.

Family and domain databases

InterProⁱ	View protein in InterPro IPR009072. Histone-fold. IPR007125. Histone_H2A/H2B/H3. IPR000164. Histone_H3/CENP-A.
PANTHERⁱ	PTHR11426. PTHR11426. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00125. Histone. 1 hit.
PRINTSⁱ	PR00622. HISTONEH3.
SMARTⁱ	View protein in SMART SM00428. H3. 1 hit.
SUPFAMⁱ	SSF47113. SSF47113. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00959. HISTONE_H3_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q6TXQ4_HUMAN
Accessionⁱ	Q6TXQ4Primary (citable) accession number: Q6TXQ4
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 5, 2004
	Last sequence update:	July 5, 2004
	Last modified:	July 5, 2017
	This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structureCombined sources

UniProtKB - Q6TXQ4 (Q6TXQ4_HUMAN)

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Functionⁱ

GO - Molecular functionⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Proteomic databases

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q6TXQ4 (Q6TXQ4_HUMAN)

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H3L-like histone

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ