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Q6TUY0 (PAP1_YMTV5) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Poly(A) polymerase catalytic subunit

EC=2.7.7.19
Alternative name(s):
Poly(A) polymerase large subunit
Short name=PAP-L
Gene names
Name:PAPL
Ordered Locus Names:32L
OrganismYaba monkey tumor virus (strain VR587) (YMTV) [Reference proteome]
Taxonomic identifier928314 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeYatapoxvirus
Virus hostErythrocebus patas (Red guenon) (Cercopithecus patas) [TaxID: 9538]
Homo sapiens (Human) [TaxID: 9606]
Macaca (macaques) [TaxID: 9539]
Papio hamadryas (Hamadryas baboon) [TaxID: 9557]

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activity

ATP + RNA(n) = diphosphate + RNA(n+1).

Subunit structure

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Sequence similarities

Belongs to the poxviridae poly(A) polymerase catalytic subunit family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 470470Poly(A) polymerase catalytic subunit
PRO_0000308942

Sites

Active site1921 By similarity
Active site1941 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6TUY0 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 523D828081B1669B

FASTA47054,614
        10         20         30         40         50         60 
MNNSITLTLK NYLGRMPTVN EYYMLKSQVR NIQKIMFFNK DIFISLIKKN KKKFFYEIKS 

        70         80         90        100        110        120 
SPSEMRLHIL EYFMKQQKTS SIGKLYAIIE LQTILVSTYT DVLGVLTTKA PYVFPSNVRY 

       130        140        150        160        170        180 
EPRSMKKIAH DILTTINVAT VSEKVMGRHN VSELVTNVNL LMEEYLRRHN KSCICYGSYS 

       190        200        210        220        230        240 
LYLLNPSIEY GDIDIMQTNS RIFLINLAFL IKFITGHNVM LLKVPYLKNY MVLRDDEDKH 

       250        260        270        280        290        300 
IIDSFNVRQD TMHSIPKILI DNIYIVDPTF QLLSMIKMFS QVDRLEDLAR NQEKATIKLA 

       310        320        330        340        350        360 
TLLEYVRVKH GIIFNGKVTN MPMPSSFDHE KRIITVDTSR YNFSFKKCFV YLDENSLSSD 

       370        380        390        400        410        420 
ILNLNADDAI DFENVSNSVF LINDEIMYTY FSNTILMSSK DEIHEISARG VSAHILMYQI 

       430        440        450        460        470 
LTDGDYLIPL SDIVNSLMFK EKIPIFSIIP RDKKTGKHGI INIEKDIITH 

« Hide

References

[1]"Complete genomic sequence and comparative analysis of the tumorigenic poxvirus Yaba monkey tumor virus."
Brunetti C.R., Amano H., Ueda Y., Qin J., Miyamura T., Suzuki T., Li X., Barrett J.W., McFadden G.
J. Virol. 77:13335-13347(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY386371 Genomic DNA. Translation: AAR07389.1.
RefSeqNP_938288.1. NC_005179.1.

3D structure databases

ProteinModelPortalQ6TUY0.
SMRQ6TUY0. Positions 9-468.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2943665.

Phylogenomic databases

ProtClustDBPHA2996.

Family and domain databases

InterProIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFPIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNetSearch...

Entry information

Entry namePAP1_YMTV5
AccessionPrimary (citable) accession number: Q6TUY0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families