ID   Q6TQE4_MOUSE            Unreviewed;       232 AA.
AC   Q6TQE4;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 122.
DE   SubName: Full=Peroxisome proliferator-activated receptor gamma 1 {ECO:0000313|EMBL:AAQ89993.1};
DE   Flags: Fragment;
GN   Name=Pparg {ECO:0000313|EMBL:AAQ89993.1};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAQ89993.1};
RN   [1] {ECO:0000313|EMBL:AAQ89993.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=AKR/J {ECO:0000313|EMBL:AAQ89992.1}, C57BL/6J
RC   {ECO:0000313|EMBL:AAQ89993.1}, and SAMP1/YitFc
RC   {ECO:0000313|EMBL:AAQ89994.1};
RA   Sugawara K., Olson T., Moskaluk C.A., Stevens B., Hoang S., Kozaiwa K.,
RA   Cominelli F., Ley K.F., McDuffie M.;
RT   "Susceptibility to Crohn's disease is linked to PPARgamma in mouse and
RT   man.";
RL   Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the nuclear hormone receptor family. NR1
CC       subfamily. {ECO:0000256|ARBA:ARBA00008092}.
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DR   EMBL; AH013272; AAQ89992.1; -; Genomic_DNA.
DR   EMBL; AY389530; AAQ89992.1; JOINED; Genomic_DNA.
DR   EMBL; AH013273; AAQ89993.1; -; Genomic_DNA.
DR   EMBL; AH013274; AAQ89994.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6TQE4; -.
DR   ChiTaRS; Pparg; mouse.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004879; F:nuclear receptor activity; IEA:InterPro.
DR   CDD; cd06932; NR_LBD_PPAR; 1.
DR   Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR   InterPro; IPR003074; 1Cnucl_rcpt.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR   PANTHER; PTHR24082; NUCLEAR HORMONE RECEPTOR; 1.
DR   PANTHER; PTHR24082:SF488; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA; 1.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   PRINTS; PR01288; PROXISOMEPAR.
DR   PRINTS; PR00398; STRDHORMONER.
DR   SMART; SM00430; HOLI; 1.
DR   SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AAQ89993.1};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          2..230
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51843"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAQ89993.1"
SQ   SEQUENCE   232 AA;  26703 MW;  E661D47B57AF083D CRC64;
     PFVIYDMNSL MMGEDKIKFK HITPLQEQSK EVAIRIFQGC QFRSVEAVQE ITEYAKNIPG
     FINLDLNDQV TLLKYGVHEI IYTMLASLMN KDGVLISEGQ GFMTREFLKS LRKPFGDFME
     PKFEFAVKFN ALELDDSDLA IFIAVIILSG DRPGLLNVKP IEDIQDNLLQ ALELQLKLNH
     PESSQLFAKV LQKMTDLRQI VTEHVQLLHV IKKTETDMSL HPLLQEIYKD LY
//