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Protein
Submitted name:

Peroxisome proliferator-activated receptor gamma 1

Gene

Pparg

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Enzyme and pathway databases

ReactomeiREACT_276696. Nuclear Receptor transcription pathway.
REACT_309805. Transcriptional regulation of white adipocyte differentiation.

Names & Taxonomyi

Protein namesi
Submitted name:
Peroxisome proliferator-activated receptor gamma 1Imported
Gene namesi
Name:PpargImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

BgeeiQ6TQE4.
ExpressionAtlasiQ6TQE4. baseline and differential.
GenevestigatoriQ6TQE4.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ6TQE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG106004.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
InterProiIPR003074. 1Cnucl_rcpt.
IPR008946. Nucl_hormone_rcpt_ligand-bd.
IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
IPR001723. Str_hrmn_rcpt.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
[Graphical view]
PRINTSiPR01288. PROXISOMEPAR.
PR00398. STRDHORMONER.
SMARTiSM00430. HOLI. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6TQE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PFVIYDMNSL MMGEDKIKFK HITPLQEQSK EVAIRIFQGC QFRSVEAVQE
60 70 80 90 100
ITEYAKNIPG FINLDLNDQV TLLKYGVHEI IYTMLASLMN KDGVLISEGQ
110 120 130 140 150
GFMTREFLKS LRKPFGDFME PKFEFAVKFN ALELDDSDLA IFIAVIILSG
160 170 180 190 200
DRPGLLNVKP IEDIQDNLLQ ALELQLKLNH PESSQLFAKV LQKMTDLRQI
210 220 230
VTEHVQLLHV IKKTETDMSL HPLLQEIYKD LY
Length:232
Mass (Da):26,703
Last modified:July 5, 2004 - v1
Checksum:iE661D47B57AF083D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY389532, AY389530 Genomic DNA. Translation: AAQ89992.1.
AY389533, AY389531 Genomic DNA. Translation: AAQ89993.1.
AY389544, AY389542 Genomic DNA. Translation: AAQ89994.1.
UniGeneiMm.3020.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY389532, AY389530 Genomic DNA. Translation: AAQ89992.1.
AY389533, AY389531 Genomic DNA. Translation: AAQ89993.1.
AY389544, AY389542 Genomic DNA. Translation: AAQ89994.1.
UniGeneiMm.3020.

3D structure databases

ProteinModelPortaliQ6TQE4.
ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiQ6TQE4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG106004.

Enzyme and pathway databases

ReactomeiREACT_276696. Nuclear Receptor transcription pathway.
REACT_309805. Transcriptional regulation of white adipocyte differentiation.

Gene expression databases

BgeeiQ6TQE4.
ExpressionAtlasiQ6TQE4. baseline and differential.
GenevestigatoriQ6TQE4.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
InterProiIPR003074. 1Cnucl_rcpt.
IPR008946. Nucl_hormone_rcpt_ligand-bd.
IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
IPR001723. Str_hrmn_rcpt.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
[Graphical view]
PRINTSiPR01288. PROXISOMEPAR.
PR00398. STRDHORMONER.
SMARTiSM00430. HOLI. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Susceptibility to Crohn's disease is linked to PPARgamma in mouse and man."
    Sugawara K., Olson T., Moskaluk C.A., Stevens B., Hoang S., Kozaiwa K., Cominelli F., Ley K.F., McDuffie M.
    Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AKR/JImported, C57BL/6JImported and SAMP1/YitFcImported.

Entry informationi

Entry nameiQ6TQE4_MOUSE
AccessioniPrimary (citable) accession number: Q6TQE4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 27, 2015
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.