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Q6TQE4 (Q6TQE4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:Pparg EMBL AAQ89993.1
OrganismMus musculus (Mouse) EMBL AAQ89993.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length232 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Biological processTranscription
Transcription regulation SAAS SAAS008946
   Cellular componentNucleus SAAS SAAS008946
   Molecular functionReceptor EMBL AAQ89993.1
Gene Ontology (GO)
   Biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process

Inferred from electronic annotation. Source: Ensembl

cell maturation

Inferred from electronic annotation. Source: Ensembl

cellular response to insulin stimulus

Inferred from electronic annotation. Source: Ensembl

fatty acid oxidation

Inferred from electronic annotation. Source: Ensembl

glucose homeostasis

Inferred from electronic annotation. Source: Ensembl

heart development

Inferred from electronic annotation. Source: Ensembl

lipoprotein transport

Inferred from electronic annotation. Source: Ensembl

low-density lipoprotein particle receptor biosynthetic process

Inferred from electronic annotation. Source: Ensembl

monocyte differentiation

Inferred from electronic annotation. Source: Ensembl

negative regulation of acute inflammatory response

Inferred from electronic annotation. Source: Ensembl

negative regulation of cell growth

Inferred from electronic annotation. Source: Ensembl

negative regulation of cholesterol storage

Inferred from electronic annotation. Source: Ensembl

negative regulation of interferon-gamma-mediated signaling pathway

Inferred from electronic annotation. Source: Ensembl

negative regulation of receptor biosynthetic process

Inferred from electronic annotation. Source: Ensembl

negative regulation of sequestering of triglyceride

Inferred from electronic annotation. Source: Ensembl

negative regulation of smooth muscle cell proliferation

Inferred from electronic annotation. Source: Ensembl

negative regulation of telomerase activity

Inferred from electronic annotation. Source: Ensembl

organ regeneration

Inferred from electronic annotation. Source: Ensembl

peroxisome proliferator activated receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

positive regulation of fatty acid oxidation

Inferred from electronic annotation. Source: Ensembl

positive regulation of oligodendrocyte differentiation

Inferred from electronic annotation. Source: Ensembl

positive regulation of sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Ensembl

regulation of blood pressure

Inferred from electronic annotation. Source: Ensembl

regulation of fat cell differentiation

Inferred from electronic annotation. Source: Ensembl

response to caffeine

Inferred from electronic annotation. Source: Ensembl

response to cold

Inferred from electronic annotation. Source: Ensembl

response to drug

Inferred from electronic annotation. Source: Ensembl

response to estrogen

Inferred from electronic annotation. Source: Ensembl

response to low-density lipoprotein particle

Inferred from electronic annotation. Source: Ensembl

response to retinoic acid

Inferred from electronic annotation. Source: Ensembl

response to vitamin A

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentcytosol

Inferred from electronic annotation. Source: Ensembl

nucleus

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functiondrug binding

Inferred from electronic annotation. Source: Ensembl

ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity

Inferred from electronic annotation. Source: InterPro

ligand-dependent nuclear receptor transcription coactivator activity

Inferred from electronic annotation. Source: Ensembl

steroid hormone receptor activity

Inferred from electronic annotation. Source: InterPro

transcription regulatory region DNA binding

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAQ89993.1

Sequences

Sequence LengthMass (Da)Tools
Q6TQE4 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: E661D47B57AF083D

FASTA23226,703
        10         20         30         40         50         60 
PFVIYDMNSL MMGEDKIKFK HITPLQEQSK EVAIRIFQGC QFRSVEAVQE ITEYAKNIPG 

        70         80         90        100        110        120 
FINLDLNDQV TLLKYGVHEI IYTMLASLMN KDGVLISEGQ GFMTREFLKS LRKPFGDFME 

       130        140        150        160        170        180 
PKFEFAVKFN ALELDDSDLA IFIAVIILSG DRPGLLNVKP IEDIQDNLLQ ALELQLKLNH 

       190        200        210        220        230 
PESSQLFAKV LQKMTDLRQI VTEHVQLLHV IKKTETDMSL HPLLQEIYKD LY 

« Hide

References

[1]"Susceptibility to Crohn's disease is linked to PPARgamma in mouse and man."
Sugawara K., Olson T., Moskaluk C.A., Stevens B., Hoang S., Kozaiwa K., Cominelli F., Ley K.F., McDuffie M.
Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: AKR/J EMBL AAQ89992.1, C57BL/6J EMBL AAQ89993.1 and SAMP1/YitFc EMBL AAQ89994.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY389532, AY389530 Genomic DNA. Translation: AAQ89992.1.
AY389533, AY389531 Genomic DNA. Translation: AAQ89993.1.
AY389544, AY389542 Genomic DNA. Translation: AAQ89994.1.
UniGeneMm.3020.

3D structure databases

ProteinModelPortalQ6TQE4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG106004.
InParanoidQ6TQE4.

Gene expression databases

ArrayExpressQ6TQE4.
GenevestigatorQ6TQE4.

Family and domain databases

Gene3D1.10.565.10. 1 hit.
InterProIPR003074. 1Cnucl_rcpt.
IPR008946. Nucl_hormone_rcpt_ligand-bd.
IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
IPR001723. Str_hrmn_rcpt.
[Graphical view]
PfamPF00104. Hormone_recep. 1 hit.
[Graphical view]
PRINTSPR01288. PROXISOMEPAR.
PR00398. STRDHORMONER.
SMARTSM00430. HOLI. 1 hit.
[Graphical view]
SUPFAMSSF48508. SSF48508. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ6TQE4_MOUSE
AccessionPrimary (citable) accession number: Q6TQE4
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)