Q6TQE4 (Q6TQE4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Peroxisome proliferator-activated receptor gamma 1 EMBL AAQ89993.1

Gene names

Name:

Pparg EMBL AAQ89993.1 MGI 97747

Organism

Mus musculus (Mouse) EMBL AAQ89993.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	232 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Transcription Transcription regulation SAAS SAAS000536
Cellular component	Nucleus SAAS SAAS000536
Molecular function	Receptor EMBL AAQ89993.1
Gene Ontology (GO)
Biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process Inferred from electronic annotation. Source: Compara cell maturation Inferred from electronic annotation. Source: Compara cellular response to insulin stimulus Inferred from electronic annotation. Source: Compara fatty acid oxidation Inferred from electronic annotation. Source: Compara glucose homeostasis Inferred from electronic annotation. Source: Compara heart development Inferred from electronic annotation. Source: Compara induction of apoptosis Inferred from electronic annotation. Source: Compara lipoprotein transport Inferred from electronic annotation. Source: Compara low-density lipoprotein particle receptor biosynthetic process Inferred from electronic annotation. Source: Compara monocyte differentiation Inferred from electronic annotation. Source: Compara negative regulation of acute inflammatory response Inferred from electronic annotation. Source: Compara negative regulation of cell growth Inferred from electronic annotation. Source: Compara negative regulation of cholesterol storage Inferred from electronic annotation. Source: Compara negative regulation of interferon-gamma-mediated signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of receptor biosynthetic process Inferred from electronic annotation. Source: Compara negative regulation of sequestering of triglyceride Inferred from electronic annotation. Source: Compara negative regulation of smooth muscle cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of telomerase activity Inferred from electronic annotation. Source: Compara organ regeneration Inferred from electronic annotation. Source: Compara peroxisome proliferator activated receptor signaling pathway Inferred from electronic annotation. Source: Compara positive regulation of fatty acid oxidation Inferred from electronic annotation. Source: Compara positive regulation of oligodendrocyte differentiation Inferred from electronic annotation. Source: Compara positive regulation of sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara regulation of blood pressure Inferred from electronic annotation. Source: Compara regulation of fat cell differentiation Inferred from electronic annotation. Source: Compara response to caffeine Inferred from electronic annotation. Source: Compara response to cold Inferred from electronic annotation. Source: Compara response to drug Inferred from electronic annotation. Source: Compara response to estrogen stimulus Inferred from electronic annotation. Source: Compara response to low-density lipoprotein particle stimulus Inferred from electronic annotation. Source: Compara response to retinoic acid Inferred from electronic annotation. Source: Compara response to vitamin A Inferred from electronic annotation. Source: Compara
Cellular_component	cytosol Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	drug binding Inferred from electronic annotation. Source: Compara ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Inferred from electronic annotation. Source: InterPro ligand-dependent nuclear receptor transcription coactivator activity Inferred from electronic annotation. Source: Compara steroid hormone receptor activity Inferred from electronic annotation. Source: InterPro transcription regulatory region DNA binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAQ89993.1

Sequences

	Sequence		Length	Mass (Da)
	Q6TQE4 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: E661D47B57AF083D	FASTA	232	26,703
	10 20 30 40 50 60 PFVIYDMNSL MMGEDKIKFK HITPLQEQSK EVAIRIFQGC QFRSVEAVQE ITEYAKNIPG 70 80 90 100 110 120 FINLDLNDQV TLLKYGVHEI IYTMLASLMN KDGVLISEGQ GFMTREFLKS LRKPFGDFME 130 140 150 160 170 180 PKFEFAVKFN ALELDDSDLA IFIAVIILSG DRPGLLNVKP IEDIQDNLLQ ALELQLKLNH 190 200 210 220 230 PESSQLFAKV LQKMTDLRQI VTEHVQLLHV IKKTETDMSL HPLLQEIYKD LY

References

[1]	"Susceptibility to Crohn's disease is linked to PPARgamma in mouse and man." Sugawara K., Olson T., Moskaluk C.A., Stevens B., Hoang S., Kozaiwa K., Cominelli F., Ley K.F., McDuffie M. Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: AKR/J EMBL AAQ89992.1, C57BL/6J EMBL AAQ89993.1 and SAMP1/YitFc EMBL AAQ89994.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY389532, AY389530 Genomic DNA. Translation: AAQ89992.1. AY389533, AY389531 Genomic DNA. Translation: AAQ89993.1. AY389544, AY389542 Genomic DNA. Translation: AAQ89994.1.
IPI	IPI00896034.
UniGene	Mm.3020.
3D structure databases
ProteinModelPortal	Q6TQE4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG106004.
InParanoid	Q6TQE4.
Gene expression databases
ArrayExpress	Q6TQE4.
Bgee	Q6TQE4.
Genevestigator	Q6TQE4.
Family and domain databases
Gene3D	1.10.565.10. 1 hit.
InterPro	IPR003074. 1Cnucl_rcpt. IPR008946. Nucl_hormone_rcpt_ligand-bd. IPR000536. Nucl_hrmn_rcpt_lig-bd_core. IPR001723. Str_hrmn_rcpt. [Graphical view]
Pfam	PF00104. Hormone_recep. 1 hit. [Graphical view]
PRINTS	PR01288. PROXISOMEPAR. PR00398. STRDHORMONER.
SMART	SM00430. HOLI. 1 hit. [Graphical view]
SUPFAM	SSF48508. Str_ncl_receptor. 1 hit.
ProtoNet	Search...
Other
BindingDB	Q6TQE4.

Entry information

Entry name

Q6TQE4_MOUSE

Accession

Primary (citable) accession number: Q6TQE4

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 29, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)