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Protein
Submitted name:

Tranglutaminase 1

Gene

TGM1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 1 Ca2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei407UniRule annotation1
Active sitei466UniRule annotation1
Active sitei489UniRule annotation1
Metal bindingi529CalciumUniRule annotation1
Metal bindingi531CalciumUniRule annotation1
Metal bindingi578CalciumUniRule annotation1
Metal bindingi583CalciumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Tranglutaminase 1Imported
Gene namesi
Name:TGM1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Structurei

3D structure databases

ProteinModelPortaliQ6TNF3
SMRiQ6TNF3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini399 – 492TGcInterPro annotationAdd BLAST94

Phylogenomic databases

eggNOGiENOG410IFMV Eukaryota
ENOG410XQEZ LUCA
HOGENOMiHOG000231695
HOVERGENiHBG004342
KOiK05619

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PfamiView protein in Pfam
PF00927 Transglut_C, 2 hits
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00547 TRANSGLUTAMINASES, 1 hit

Sequencei

Sequence statusi: Complete.

Q6TNF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSPTPSSGG PRSDVGRWGG NPWQPPTTPS PEPEPEPDRR SRRGGRSFWA
60 70 80 90 100
RCCGCCSCRN TEDDDWGPER HGDRGGRGSG SRNRRPDSRG SDSRQPGSRD
110 120 130 140 150
SRRPGSRDSR RPGSRDSRRP GSRGSAVNAA GDGTIREGML VVTGVDLLSS
160 170 180 190 200
RSDQNRREHH TDEFEYDELI LRRGQPFQMV LFLSRPYESS DHVTLELCIG
210 220 230 240 250
NNPEVGKGTH VIIPVGKGGS GGWKAQVTKS SGQNLNLRVH TSPNAIIGKF
260 270 280 290 300
QFTIRTRCEA GEFQLPFDPR NEIYILFNPW CPEDIVYVDH EDWRQEYVLN
310 320 330 340 350
ESGRIYYGTE AQIGERTWNY GQFDHGVLDA CLYILDRRGM PYGGRGDPVS
360 370 380 390 400
VSRVISAMVN SLDDNGVLIG NWSGDYSRGT NPSAWVGSVE ILLSYLRTGN
410 420 430 440 450
SVPFGQCWVF AGVTTTVLRC LGLATRTVTN FNSAHDTDTS LTMDIYFDEN
460 470 480 490 500
MKPLEHLNHD SVWNFHVWND CWMKRPDLPS GFDGWQVVDA TPQETSSGIF
510 520 530 540 550
CCGPCSVQSI KNGLVYMKYD TPFIFAEVNS DKVYWQRQDD GSFKIVYVEE
560 570 580 590 600
KAIGSLIITK AIGSNMREDI THTYKHPEGS EAERKAVETA AAHGSKPNVY
610 620 630 640 650
ATRDSAEDVA VQVEAQDAVM GQDLMVSVVL TNRGSSLRTV KLHLYLSVTF
660 670 680 690 700
YTGVTGSVFK ESKKEVVLAP GASERVTMPV AYKEYRVHLV DQGAMLLNIS
710 720 730 740 750
GHVKENGQVL AKQHTFRLRT PDLSLTLLGA AVVGQECEVQ IVFKNPLPVT
760 770 780 790 800
LTNVVFRLEG SGLQRPKILN VGDIGGNETV TLRQTFVPVR PGPRQLIASL
810 820 830 840
DSPQLSQVHG VIQVDVAPAS GGGAFSDIRG SGRSGETIPM ASRGGA
Length:846
Mass (Da):93,105
Last modified:July 5, 2005 - v4
Checksum:i31B4A675365C4849
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY676606 mRNA Translation: AAR26246.2
RefSeqiNP_001010991.1, NM_001010991.1
UniGeneiBt.736

Genome annotation databases

GeneIDi407997
KEGGibta:407997

Similar proteinsi

Entry informationi

Entry nameiQ6TNF3_BOVIN
AccessioniPrimary (citable) accession number: Q6TNF3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2005
Last modified: May 23, 2018
This is version 87 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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