Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q6TLV9 (Q6TLV9_CHICK) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length837 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 RGS domain. RuleBase RU003298

Contains RGS domain. SAAS SAAS024066

Ontologies

Gene Ontology (GO)
   Biological_processWnt signaling pathway involved in somitogenesis

Inferred from Biological aspect of Ancestor. Source: RefGenome

cell death

Inferred from Biological aspect of Ancestor. Source: RefGenome

cellular response to organic cyclic compound

Inferred from Biological aspect of Ancestor. Source: RefGenome

dorsal/ventral axis specification

Inferred from Biological aspect of Ancestor. Source: RefGenome

intramembranous ossification

Inferred from Biological aspect of Ancestor. Source: RefGenome

negative regulation of canonical Wnt signaling pathway

Inferred from Biological aspect of Ancestor. Source: RefGenome

negative regulation of osteoblast differentiation

Inferred from Biological aspect of Ancestor. Source: RefGenome

positive regulation of GTPase activity

Inferred from Biological aspect of Ancestor. Source: GOC

regulation of catenin import into nucleus

Inferred from Biological aspect of Ancestor. Source: RefGenome

termination of G-protein coupled receptor signaling pathway

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcell cortex

Inferred from Biological aspect of Ancestor. Source: RefGenome

cytoplasmic membrane-bounded vesicle

Inferred from Biological aspect of Ancestor. Source: RefGenome

cytoplasmic microtubule

Inferred from Biological aspect of Ancestor. Source: RefGenome

plasma membrane

Inferred from Biological aspect of Ancestor. Source: RefGenome

postsynaptic density

Inferred from Biological aspect of Ancestor. Source: RefGenome

   Molecular_functionGTPase activator activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

armadillo repeat domain binding

Inferred from Biological aspect of Ancestor. Source: RefGenome

beta-catenin binding

Inferred from Biological aspect of Ancestor. Source: RefGenome

protein kinase binding

Inferred from Biological aspect of Ancestor. Source: RefGenome

signal transducer activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q6TLV9 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: AFAC281E7C85257E

FASTA83792,943
        10         20         30         40         50         60 
MSSAVLLAHL PDPGSSFRED APRPPVPGEE GDAPPCPQPH SSFLAKSQSF PAMPVPAAPR 

        70         80         90        100        110        120 
RNENGLGEPE GSASPDSPLA RWTKSLHSLL GDQDGAYLFR TFLEREKCVD TLDFWFACNG 

       130        140        150        160        170        180 
FRQMDLKDTK TSRVAKAIYK RYIENNSIVS KQLKPATKTY IRDSIKKQQI DSIMFDQAQT 

       190        200        210        220        230        240 
EIQTVMEENA YQMFLTSDIY LEYVRSGGEN PAYMSSNGLG SLKVVCGYLP TLNEEEEWSC 

       250        260        270        280        290        300 
ADFKSKMLPS VVGLSSKTLR VTAGVRATET LENGYRSFKR NDPVNPYHVS SGYVFAPATS 

       310        320        330        340        350        360 
ANDSEISSDA LTDDSMSMTD SSVDGIPPYR IGSKKQLQRE MHRSVKANGQ VSLPHFPRTH 

       370        380        390        400        410        420 
RLPKEMTPVE PAAFAAELIS RLEKLKQEQE TMDSLEERLQ QIKEDEEKEG LELPASLQSS 

       430        440        450        460        470        480 
REMVNPQHQQ HPLSLLPSGS YEEDPQAILD EHLSRVLKTP GCQSPGMGRH SPRARSPDHL 

       490        500        510        520        530        540 
LGGKLQPSTA SPATCALLGK GFITKQTTKH VHHHYIHHHA VPKTKEQIEA EAAQRVQCCC 

       550        560        570        580        590        600 
PAGSDYYCFS KCKGHPKGTD PPLPPLEPFG RTGTLTKRPG RGVESIALLP GDGGLPGPSG 

       610        620        630        640        650        660 
VQLPGGEADR AQNVWQWMLE SERQNKHKPH STQSTKKAYS SDFAKGAPSE RPGRHHPWGP 

       670        680        690        700        710        720 
GSHPRGAQPA HPFIQDPAMP PLTPPNTLAQ LEEACRRLAE VSKPQKQRCS TSNQQRDRNH 

       730        740        750        760        770        780 
STAVQGGNTP FCNASLTTED HKEPKKLPVV HTSQSSELVV TYFFCGEEIP YRRMLKAQSL 

       790        800        810        820        830 
TLGHFKEQLS KKGNYRYYFK KASDEFDCGA VFEEIWEDET ILPMYEGRIL GKVERID 

« Hide

References

[1]"Cloning and embryonic expression of avian Axin2."
Ding L., Gamel A.J., Dai F., Yusuf F., Brand-Saberi B.E.M.
Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY394491 mRNA. Translation: AAQ84522.1.
RefSeqNP_989822.1. NM_204491.1.
UniGeneGga.8363.

3D structure databases

ProteinModelPortalQ6TLV9.
SMRQ6TLV9. Positions 71-211, 758-837.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9031.ENSGALP00000006394.

Proteomic databases

PaxDbQ6TLV9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID395152.
KEGGgga:395152.

Organism-specific databases

CTD8313.

Phylogenomic databases

eggNOGNOG238205.
HOGENOMHOG000231228.
HOVERGENHBG004324.
InParanoidQ6TLV9.
KOK04385.
PhylomeDBQ6TLV9.

Family and domain databases

Gene3D1.10.196.10. 2 hits.
InterProIPR014936. Axin_b-cat-bd.
IPR001158. DIX.
IPR024066. Regulat_G_prot_signal_dom1.
IPR016137. Regulat_G_prot_signal_superfam.
IPR000342. RGS_dom.
[Graphical view]
PfamPF08833. Axin_b-cat_bind. 1 hit.
PF00778. DIX. 1 hit.
PF00615. RGS. 1 hit.
[Graphical view]
PRINTSPR01301. RGSPROTEIN.
SMARTSM00021. DAX. 1 hit.
SM00315. RGS. 1 hit.
[Graphical view]
SUPFAMSSF48097. SSF48097. 1 hit.
PROSITEPS50841. DIX. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20815243.

Entry information

Entry nameQ6TLV9_CHICK
AccessionPrimary (citable) accession number: Q6TLV9
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)