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Protein
Submitted name:

Axin-related protein

Gene

AXIN2

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Biological processWnt signaling pathwayPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Axin-related proteinImported
Gene namesi
Name:AXIN2Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Structurei

3D structure databases

ProteinModelPortaliQ6TLV9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini85 – 204RGSInterPro annotationAdd BLAST120
Domaini755 – 837DIXInterPro annotationAdd BLAST83

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili375 – 412Sequence analysisAdd BLAST38

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3589 Eukaryota
ENOG410YMJD LUCA
HOGENOMiHOG000231228
HOVERGENiHBG004324
KOiK04385
PhylomeDBiQ6TLV9

Family and domain databases

CDDicd11582 Axin_TNKS_binding, 1 hit
Gene3Di1.10.196.10, 1 hit
3.10.20.380, 1 hit
InterProiView protein in InterPro
IPR014936 Axin_b-cat-bd
IPR032101 Axin_TNKS-bd
IPR001158 DIX
IPR038207 DIX_dom_sf
IPR016137 RGS
IPR036305 RGS_sf
IPR024066 RGS_subdom1/3
IPR029071 Ubiquitin-like_domsf
PfamiView protein in Pfam
PF16646 AXIN1_TNKS_BD, 1 hit
PF08833 Axin_b-cat_bind, 1 hit
PF00778 DIX, 1 hit
PF00615 RGS, 1 hit
PRINTSiPR01301 RGSPROTEIN
SMARTiView protein in SMART
SM00021 DAX, 1 hit
SM00315 RGS, 1 hit
SUPFAMiSSF48097 SSF48097, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50841 DIX, 1 hit
PS50132 RGS, 1 hit

Sequencei

Sequence statusi: Complete.

Q6TLV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSAVLLAHL PDPGSSFRED APRPPVPGEE GDAPPCPQPH SSFLAKSQSF
60 70 80 90 100
PAMPVPAAPR RNENGLGEPE GSASPDSPLA RWTKSLHSLL GDQDGAYLFR
110 120 130 140 150
TFLEREKCVD TLDFWFACNG FRQMDLKDTK TSRVAKAIYK RYIENNSIVS
160 170 180 190 200
KQLKPATKTY IRDSIKKQQI DSIMFDQAQT EIQTVMEENA YQMFLTSDIY
210 220 230 240 250
LEYVRSGGEN PAYMSSNGLG SLKVVCGYLP TLNEEEEWSC ADFKSKMLPS
260 270 280 290 300
VVGLSSKTLR VTAGVRATET LENGYRSFKR NDPVNPYHVS SGYVFAPATS
310 320 330 340 350
ANDSEISSDA LTDDSMSMTD SSVDGIPPYR IGSKKQLQRE MHRSVKANGQ
360 370 380 390 400
VSLPHFPRTH RLPKEMTPVE PAAFAAELIS RLEKLKQEQE TMDSLEERLQ
410 420 430 440 450
QIKEDEEKEG LELPASLQSS REMVNPQHQQ HPLSLLPSGS YEEDPQAILD
460 470 480 490 500
EHLSRVLKTP GCQSPGMGRH SPRARSPDHL LGGKLQPSTA SPATCALLGK
510 520 530 540 550
GFITKQTTKH VHHHYIHHHA VPKTKEQIEA EAAQRVQCCC PAGSDYYCFS
560 570 580 590 600
KCKGHPKGTD PPLPPLEPFG RTGTLTKRPG RGVESIALLP GDGGLPGPSG
610 620 630 640 650
VQLPGGEADR AQNVWQWMLE SERQNKHKPH STQSTKKAYS SDFAKGAPSE
660 670 680 690 700
RPGRHHPWGP GSHPRGAQPA HPFIQDPAMP PLTPPNTLAQ LEEACRRLAE
710 720 730 740 750
VSKPQKQRCS TSNQQRDRNH STAVQGGNTP FCNASLTTED HKEPKKLPVV
760 770 780 790 800
HTSQSSELVV TYFFCGEEIP YRRMLKAQSL TLGHFKEQLS KKGNYRYYFK
810 820 830
KASDEFDCGA VFEEIWEDET ILPMYEGRIL GKVERID
Length:837
Mass (Da):92,943
Last modified:July 5, 2004 - v1
Checksum:iAFAC281E7C85257E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY394491 mRNA Translation: AAQ84522.1
RefSeqiNP_989822.1, NM_204491.1
UniGeneiGga.8363

Genome annotation databases

GeneIDi395152
KEGGigga:395152

Similar proteinsi

Entry informationi

Entry nameiQ6TLV9_CHICK
AccessioniPrimary (citable) accession number: Q6TLV9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health