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Q6TKQ0

- Q6TKQ0_HUMAN

UniProt

Q6TKQ0 - Q6TKQ0_HUMAN

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Protein
Submitted name: Patched
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. heparin binding Source: Ensembl

GO - Biological processi

  1. brain development Source: Ensembl
  2. branching involved in ureteric bud morphogenesis Source: Ensembl
  3. cell differentiation involved in kidney development Source: Ensembl
  4. cell proliferation involved in metanephros development Source: Ensembl
  5. cellular response to cholesterol Source: Ensembl
  6. embryonic limb morphogenesis Source: Ensembl
  7. epidermis development Source: Ensembl
  8. glucose homeostasis Source: Ensembl
  9. heart morphogenesis Source: Ensembl
  10. hindlimb morphogenesis Source: Ensembl
  11. keratinocyte proliferation Source: Ensembl
  12. mammary gland duct morphogenesis Source: Ensembl
  13. mammary gland epithelial cell differentiation Source: Ensembl
  14. negative regulation of cell division Source: Ensembl
  15. negative regulation of epithelial cell proliferation Source: Ensembl
  16. negative regulation of multicellular organism growth Source: Ensembl
  17. neural plate axis specification Source: Ensembl
  18. neural tube closure Source: Ensembl
  19. protein processing Source: Ensembl
  20. regulation of mitotic cell cycle Source: Ensembl
  21. regulation of protein localization Source: Ensembl
  22. regulation of smoothened signaling pathway Source: Ensembl
  23. response to chlorate Source: Ensembl
  24. response to drug Source: Ensembl
  25. response to estradiol Source: Ensembl
  26. response to mechanical stimulus Source: Ensembl
  27. response to retinoic acid Source: Ensembl
  28. smoothened signaling pathway involved in dorsal/ventral neural tube patterning Source: Ensembl
  29. somite development Source: Ensembl
  30. spinal cord motor neuron differentiation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PatchedImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. axonal growth cone Source: Ensembl
  2. dendritic growth cone Source: Ensembl
  3. midbody Source: Ensembl
  4. plasma membrane Source: Ensembl
  5. postsynaptic density Source: Ensembl
  6. primary cilium Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ6TKQ0.

Expressioni

Gene expression databases

ArrayExpressiQ6TKQ0.
BgeeiQ6TKQ0.

Sequencei

Sequence statusi: Fragment.

Q6TKQ0-1 [UniParc]FASTAAdd to Basket

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GKPPLRWTNF DPLEFLEELK KINYQVDSWE EMLNKAEVGH GYMDRPCLNP    50
ADPDCPATAP NKNSTKPLDM ALVLNGGCHG LSRKYMHWQE ELIVGGTVKN 100
STGKLV 106
Length:106
Mass (Da):11,897
Last modified:July 5, 2004 - v1
Checksum:i8D20CA6BA038CBCB
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei106 – 1061Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY395758, AY395757 Genomic DNA. Translation: AAR21238.1.
UniGeneiHs.494538.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY395758 , AY395757 Genomic DNA. Translation: AAR21238.1 .
UniGenei Hs.494538.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q6TKQ0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

ArrayExpressi Q6TKQ0.
Bgeei Q6TKQ0.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Sequencing of Candidate Genes for Non-Syndromic Cleft Lip and Palate."
    Mansilla M.A., Vieira A.R., Murray J.C.
    Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6TKQ0_HUMAN
AccessioniPrimary (citable) accession number: Q6TKQ0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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