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Q6TKQ0

- Q6TKQ0_HUMAN

UniProt

Q6TKQ0 - Q6TKQ0_HUMAN

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Protein
Submitted name:

Patched

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. heparin binding Source: Ensembl

GO - Biological processi

  1. brain development Source: Ensembl
  2. branching involved in ureteric bud morphogenesis Source: Ensembl
  3. cell differentiation involved in kidney development Source: Ensembl
  4. cell proliferation involved in metanephros development Source: Ensembl
  5. cellular response to cholesterol Source: Ensembl
  6. embryonic limb morphogenesis Source: Ensembl
  7. embryonic organ development Source: Ensembl
  8. epidermis development Source: Ensembl
  9. glucose homeostasis Source: Ensembl
  10. heart morphogenesis Source: Ensembl
  11. hindlimb morphogenesis Source: Ensembl
  12. in utero embryonic development Source: Ensembl
  13. keratinocyte proliferation Source: Ensembl
  14. mammary gland duct morphogenesis Source: Ensembl
  15. mammary gland epithelial cell differentiation Source: Ensembl
  16. negative regulation of cell division Source: Ensembl
  17. negative regulation of epithelial cell proliferation Source: Ensembl
  18. negative regulation of multicellular organism growth Source: Ensembl
  19. neural plate axis specification Source: Ensembl
  20. neural tube closure Source: Ensembl
  21. protein processing Source: Ensembl
  22. regulation of mitotic cell cycle Source: Ensembl
  23. regulation of protein localization Source: Ensembl
  24. regulation of smoothened signaling pathway Source: Ensembl
  25. response to chlorate Source: Ensembl
  26. response to drug Source: Ensembl
  27. response to estradiol Source: Ensembl
  28. response to mechanical stimulus Source: Ensembl
  29. response to retinoic acid Source: Ensembl
  30. smoothened signaling pathway involved in dorsal/ventral neural tube patterning Source: Ensembl
  31. somite development Source: Ensembl
  32. spinal cord motor neuron differentiation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PatchedImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. axonal growth cone Source: Ensembl
  2. dendritic growth cone Source: Ensembl
  3. midbody Source: Ensembl
  4. plasma membrane Source: Ensembl
  5. postsynaptic density Source: Ensembl
  6. primary cilium Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ6TKQ0.

Expressioni

Gene expression databases

BgeeiQ6TKQ0.
ExpressionAtlasiQ6TKQ0. baseline and differential.

Sequencei

Sequence statusi: Fragment.

Q6TKQ0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
GKPPLRWTNF DPLEFLEELK KINYQVDSWE EMLNKAEVGH GYMDRPCLNP
60 70 80 90 100
ADPDCPATAP NKNSTKPLDM ALVLNGGCHG LSRKYMHWQE ELIVGGTVKN

STGKLV
Length:106
Mass (Da):11,897
Last modified:July 5, 2004 - v1
Checksum:i8D20CA6BA038CBCB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei106 – 1061Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY395758, AY395757 Genomic DNA. Translation: AAR21238.1.
UniGeneiHs.494538.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY395758 , AY395757 Genomic DNA. Translation: AAR21238.1 .
UniGenei Hs.494538.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q6TKQ0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

Bgeei Q6TKQ0.
ExpressionAtlasi Q6TKQ0. baseline and differential.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Sequencing of Candidate Genes for Non-Syndromic Cleft Lip and Palate."
    Mansilla M.A., Vieira A.R., Murray J.C.
    Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6TKQ0_HUMAN
AccessioniPrimary (citable) accession number: Q6TKQ0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.