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Q6TKQ0

- Q6TKQ0_HUMAN

UniProt

Q6TKQ0 - Q6TKQ0_HUMAN

Protein
Submitted name:

Patched

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. heparin binding Source: Ensembl

    GO - Biological processi

    1. brain development Source: Ensembl
    2. branching involved in ureteric bud morphogenesis Source: Ensembl
    3. cell differentiation involved in kidney development Source: Ensembl
    4. cell proliferation involved in metanephros development Source: Ensembl
    5. cellular response to cholesterol Source: Ensembl
    6. embryonic limb morphogenesis Source: Ensembl
    7. epidermis development Source: Ensembl
    8. glucose homeostasis Source: Ensembl
    9. heart morphogenesis Source: Ensembl
    10. hindlimb morphogenesis Source: Ensembl
    11. keratinocyte proliferation Source: Ensembl
    12. mammary gland duct morphogenesis Source: Ensembl
    13. mammary gland epithelial cell differentiation Source: Ensembl
    14. negative regulation of cell division Source: Ensembl
    15. negative regulation of epithelial cell proliferation Source: Ensembl
    16. negative regulation of multicellular organism growth Source: Ensembl
    17. neural plate axis specification Source: Ensembl
    18. neural tube closure Source: Ensembl
    19. protein processing Source: Ensembl
    20. regulation of mitotic cell cycle Source: Ensembl
    21. regulation of protein localization Source: Ensembl
    22. regulation of smoothened signaling pathway Source: Ensembl
    23. response to chlorate Source: Ensembl
    24. response to drug Source: Ensembl
    25. response to estradiol Source: Ensembl
    26. response to mechanical stimulus Source: Ensembl
    27. response to retinoic acid Source: Ensembl
    28. smoothened signaling pathway involved in dorsal/ventral neural tube patterning Source: Ensembl
    29. somite development Source: Ensembl
    30. spinal cord motor neuron differentiation Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PatchedImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. axonal growth cone Source: Ensembl
    2. dendritic growth cone Source: Ensembl
    3. midbody Source: Ensembl
    4. plasma membrane Source: Ensembl
    5. postsynaptic density Source: Ensembl
    6. primary cilium Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ6TKQ0.

    Expressioni

    Gene expression databases

    ArrayExpressiQ6TKQ0.
    BgeeiQ6TKQ0.

    Sequencei

    Sequence statusi: Fragment.

    Q6TKQ0-1 [UniParc]FASTAAdd to Basket

    « Hide

    GKPPLRWTNF DPLEFLEELK KINYQVDSWE EMLNKAEVGH GYMDRPCLNP    50
    ADPDCPATAP NKNSTKPLDM ALVLNGGCHG LSRKYMHWQE ELIVGGTVKN 100
    STGKLV 106
    Length:106
    Mass (Da):11,897
    Last modified:July 5, 2004 - v1
    Checksum:i8D20CA6BA038CBCB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei106 – 1061Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY395758, AY395757 Genomic DNA. Translation: AAR21238.1.
    UniGeneiHs.494538.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY395758 , AY395757 Genomic DNA. Translation: AAR21238.1 .
    UniGenei Hs.494538.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q6TKQ0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Gene expression databases

    ArrayExpressi Q6TKQ0.
    Bgeei Q6TKQ0.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Sequencing of Candidate Genes for Non-Syndromic Cleft Lip and Palate."
      Mansilla M.A., Vieira A.R., Murray J.C.
      Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ6TKQ0_HUMAN
    AccessioniPrimary (citable) accession number: Q6TKQ0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.