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Protein

POU domain protein

Gene

pou1f1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cell fate specification Source: ZFIN
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

TranscriptionUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:pou1f1Imported
Synonyms:pit1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 9

Organism-specific databases

ZFINiZDB-GENE-040630-7. pou1f1.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000058924.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000076317.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini186 – 260POU-specificInterPro annotationAdd BLAST75
Domaini274 – 334Homeobox DNA-bindingInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotation
Contains 1 POU-specific domain.UniRule annotation
Contains 1 homeobox DNA-binding domain.UniRule annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.
HOGENOMiHOG000116302.
HOVERGENiHBG053120.
KOiK09363.
OMAiACKLKSI.
OrthoDBiEOG091G0U0S.
TreeFamiTF316413.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR015586. Pit_1.
IPR013847. POU.
IPR000327. POU_dom.
[Graphical view]
PANTHERiPTHR11636:SF84. PTHR11636:SF84. 1 hit.
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6TGI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCQAFSTSD SFSGLGGDTG AALPLLMHHS AAADCHNTNI CSTVPSGLPL
60 70 80 90 100
VQSSKRSHMH LSTSALGNAS ASLHYPMPPC HYSNQQTTYG MMAAQEMLSA
110 120 130 140 150
SISQTRILQT CSVPHANMVN GANSLQGALA PRLYKFPEHS LAGGSCALSH
160 170 180 190 200
GFAPLPQTLL TDEPILGDIK QELRRKSRTL DETPDMDSPQ IRELEKFAND
210 220 230 240 250
FKLRRIKLGY TQTNVGEALA AVHGSEFSQT TICRFENLQL SFKNACKLKS
260 270 280 290 300
ILAKWLEEAE QAGALFNEKM GLHERKRKRR TTISLGAKEA LERSFVEKSK
310 320 330 340 350
PSSQEIVRMA EGLHLEKEVV RVWFCNRRQR EKRVKTSLHH SSFMTKDCRA
Length:350
Mass (Da):38,731
Last modified:July 5, 2004 - v1
Checksum:iBCB2A949D450EF84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR361551 Genomic DNA. No translation available.
BC162244 mRNA. Translation: AAI62244.1.
AY421970 mRNA. Translation: AAQ90147.1.
RefSeqiNP_998016.1. NM_212851.1.
UniGeneiDr.89712.

Genome annotation databases

EnsembliENSDART00000081878; ENSDARP00000076317; ENSDARG00000058924.
GeneIDi405777.
KEGGidre:405777.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR361551 Genomic DNA. No translation available.
BC162244 mRNA. Translation: AAI62244.1.
AY421970 mRNA. Translation: AAQ90147.1.
RefSeqiNP_998016.1. NM_212851.1.
UniGeneiDr.89712.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000076317.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000081878; ENSDARP00000076317; ENSDARG00000058924.
GeneIDi405777.
KEGGidre:405777.

Organism-specific databases

CTDi5449.
ZFINiZDB-GENE-040630-7. pou1f1.

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.
HOGENOMiHOG000116302.
HOVERGENiHBG053120.
KOiK09363.
OMAiACKLKSI.
OrthoDBiEOG091G0U0S.
TreeFamiTF316413.

Gene expression databases

BgeeiENSDARG00000058924.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR015586. Pit_1.
IPR013847. POU.
IPR000327. POU_dom.
[Graphical view]
PANTHERiPTHR11636:SF84. PTHR11636:SF84. 1 hit.
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6TGI4_DANRE
AccessioniPrimary (citable) accession number: Q6TGI4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 30, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.