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Protein

POU domain protein

Gene

pou1f1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi276 – 335HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

  • cell fate specification Source: ZFIN
  • transcription, DNA-templated Source: UniProtKB-UniRule

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:pou1f1Imported
Synonyms:pit1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 9

Organism-specific databases

ZFINiZDB-GENE-040630-7 pou1f1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000058924

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000076317

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini186 – 260POU-specificInterPro annotationAdd BLAST75
Domaini274 – 334HomeoboxInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802 Eukaryota
ENOG410XQ7X LUCA
GeneTreeiENSGT00760000118935
HOGENOMiHOG000116302
HOVERGENiHBG053120
KOiK09363
OMAiMSCQPFT
OrthoDBiEOG091G0U0S
TreeFamiTF316413

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
IPR015586 Pit_1
IPR013847 POU
IPR000327 POU_dom
PANTHERiPTHR11636:SF84 PTHR11636:SF84, 1 hit
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF00157 Pou, 1 hit
PRINTSiPR00028 POUDOMAIN
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SM00352 POU, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS00035 POU_1, 1 hit
PS00465 POU_2, 1 hit
PS51179 POU_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q6TGI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCQAFSTSD SFSGLGGDTG AALPLLMHHS AAADCHNTNI CSTVPSGLPL
60 70 80 90 100
VQSSKRSHMH LSTSALGNAS ASLHYPMPPC HYSNQQTTYG MMAAQEMLSA
110 120 130 140 150
SISQTRILQT CSVPHANMVN GANSLQGALA PRLYKFPEHS LAGGSCALSH
160 170 180 190 200
GFAPLPQTLL TDEPILGDIK QELRRKSRTL DETPDMDSPQ IRELEKFAND
210 220 230 240 250
FKLRRIKLGY TQTNVGEALA AVHGSEFSQT TICRFENLQL SFKNACKLKS
260 270 280 290 300
ILAKWLEEAE QAGALFNEKM GLHERKRKRR TTISLGAKEA LERSFVEKSK
310 320 330 340 350
PSSQEIVRMA EGLHLEKEVV RVWFCNRRQR EKRVKTSLHH SSFMTKDCRA
Length:350
Mass (Da):38,731
Last modified:July 5, 2004 - v1
Checksum:iBCB2A949D450EF84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR361551 Genomic DNA No translation available.
BC162244 mRNA Translation: AAI62244.1
AY421970 mRNA Translation: AAQ90147.1
RefSeqiNP_998016.1, NM_212851.1
UniGeneiDr.89712

Genome annotation databases

EnsembliENSDART00000081878; ENSDARP00000076317; ENSDARG00000058924
GeneIDi405777
KEGGidre:405777

Similar proteinsi

Entry informationi

Entry nameiQ6TGI4_DANRE
AccessioniPrimary (citable) accession number: Q6TGI4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health