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Protein
Submitted name:

Jun oncogene

Gene

Jun

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. cAMP response element binding Source: MGI
  2. chromatin binding Source: MGI
  3. DNA binding Source: MGI
  4. enzyme binding Source: MGI
  5. poly(A) RNA binding Source: MGI
  6. RNA polymerase II activating transcription factor binding Source: MGI
  7. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: GO_Central
  8. RNA polymerase II distal enhancer sequence-specific DNA binding Source: MGI
  9. RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Source: MGI
  10. R-SMAD binding Source: MGI
  11. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: GO_Central
  12. sequence-specific DNA binding transcription factor activity Source: MGI
  13. transcription coactivator activity Source: MGI
  14. transcription factor binding Source: MGI
  15. transcription regulatory region DNA binding Source: MGI

GO - Biological processi

  1. angiogenesis Source: MGI
  2. axon regeneration Source: MGI
  3. cellular process Source: MGI
  4. cellular response to calcium ion Source: MGI
  5. cellular response to hormone stimulus Source: GO_Central
  6. leading edge cell differentiation Source: MGI
  7. liver development Source: MGI
  8. microglial cell activation Source: MGI
  9. monocyte differentiation Source: MGI
  10. negative regulation by host of viral transcription Source: MGI
  11. negative regulation of apoptotic process Source: MGI
  12. negative regulation of cell proliferation Source: MGI
  13. negative regulation of DNA binding Source: MGI
  14. negative regulation of neuron apoptotic process Source: MGI
  15. negative regulation of protein autophosphorylation Source: MGI
  16. negative regulation of transcription, DNA-templated Source: MGI
  17. negative regulation of transcription from RNA polymerase II promoter Source: GO_Central
  18. negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress Source: MGI
  19. outflow tract morphogenesis Source: MGI
  20. positive regulation by host of viral transcription Source: MGI
  21. positive regulation of cell differentiation Source: GO_Central
  22. positive regulation of endothelial cell proliferation Source: MGI
  23. positive regulation of fibroblast proliferation Source: MGI
  24. positive regulation of transcription, DNA-templated Source: MGI
  25. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  26. regulation of cell cycle Source: MGI
  27. regulation of transcription, DNA-templated Source: MGI
  28. response to cAMP Source: GO_Central
  29. response to cytokine Source: GO_Central
  30. response to drug Source: MGI
  31. response to lipopolysaccharide Source: GO_Central
  32. response to muscle stretch Source: MGI
  33. response to radiation Source: GO_Central
  34. SMAD protein import into nucleus Source: MGI
  35. SMAD protein signal transduction Source: MGI
  36. transcription from RNA polymerase II promoter Source: GOC
  37. transforming growth factor beta receptor signaling pathway Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Jun oncogeneImported
Gene namesi
Name:JunImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96646. Jun.

Subcellular locationi

GO - Cellular componenti

  1. nuclear chromatin Source: GO_Central
  2. nuclear euchromatin Source: MGI
  3. nucleoplasm Source: MGI
  4. nucleus Source: MGI
  5. transcriptional repressor complex Source: MGI
  6. transcription factor complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ6TDG5.

Sequencei

Sequence statusi: Fragment.

Length:14
Mass (Da):1,637
Last modified:July 5, 2004 - v1
Checksum:i8663BB5DFE02E8B1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei14 – 141Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY423853 mRNA. Translation: AAR00344.1.
UniGeneiMm.275071.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY423853 mRNA. Translation: AAR00344.1.
UniGeneiMm.275071.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:96646. Jun.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

GenevestigatoriQ6TDG5.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Immediate early gene expression."
    Gerhauser I., Ulrich R., Baumgartner W.
    Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SJL/JImported.
    Tissue: UterusImported.

Entry informationi

Entry nameiQ6TDG5_MOUSE
AccessioniPrimary (citable) accession number: Q6TDG5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 29, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.