Unreviewed, UniProtKB/TrEMBL Q6TDG3 (Q6TDG3_MOUSE)

Names and origin

Protein names

Submitted name:
    Tumor necrosis factor alpha EMBL AAR00346.1

Gene names

Name:

Tnf MGI 104798

Organism

Mus musculus (Mouse) EMBL AAR00346.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	67 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	JNK cascade Inferred from genetic interaction. Source: MGI calcium-mediated signaling Inferred from electronic annotation. Source: Compara cell activation Inferred from electronic annotation. Source: Compara cellular extravasation Inferred from direct assay. Source: MGI defense response to bacterium Inferred from direct assay. Source: MGI epithelial cell proliferation involved in salivary gland morphogenesis Inferred from direct assay. Source: MGI extracellular matrix organization Inferred from direct assay. Source: MGI glucose metabolic process Inferred from direct assay. Source: MGI humoral immune response Inferred from mutant phenotype. Source: MGI induction of apoptosis via death domain receptors Inferred from genetic interaction. Source: MGI inflammatory response Traceable author statement. Source: MGI negative regulation of L-glutamate transport Inferred from electronic annotation. Source: Compara negative regulation of cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of glucose import Inferred from direct assay. Source: MGI negative regulation of transcription from RNA polymerase II promoter Inferred from direct assay. Source: MGI organ morphogenesis Inferred from mutant phenotype. Source: MGI osteoclast differentiation Inferred from genetic interaction. Source: MGI positive regulation of I-kappaB kinase/NF-kappaB cascade Inferred from direct assay. Source: MGI positive regulation of JNK cascade Inferred from direct assay. Source: MGI positive regulation of cell proliferation Traceable author statement. Source: MGI positive regulation of interleukin-6 production Inferred from direct assay. Source: MGI positive regulation of mitosis Inferred from electronic annotation. Source: Compara positive regulation of neuron apoptosis Inferred from electronic annotation. Source: Compara positive regulation of protein transport Inferred from electronic annotation. Source: Compara positive regulation of synaptic transmission Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from direct assay. Source: MGI positive regulation of translational initiation by iron Inferred from direct assay. Source: MGI regulation of branching involved in salivary gland morphogenesis Inferred from direct assay. Source: MGI regulation of immunoglobulin secretion Inferred from direct assay. Source: MGI regulation of osteoclast differentiation Inferred from direct assay. Source: MGI regulation of protein amino acid phosphorylation Inferred from direct assay. Source: MGI response to mechanical stimulus Inferred from electronic annotation. Source: Compara transformed cell apoptosis Traceable author statement. Source: MGI tumor necrosis factor-mediated signaling pathway Inferred from direct assay. Source: MGI
Cellular component	extracellular space Inferred from direct assay. Source: MGI integral to plasma membrane Traceable author statement. Source: MGI secretory granule Traceable author statement. Source: MGI
Molecular function	cytokine activity Inferred from direct assay. Source: MGI tumor necrosis factor receptor binding Inferred from direct assay. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAR00346.1
	Non-terminal residue	67	1	EMBL AAR00346.1

Sequences

	Sequence		Length	Mass (Da)
	Q6TDG3-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 2E859416CF726B8E	FASTA	67	7,185
	10 20 30 40 50 60 LFSFLLVAGA TTLFCLLNFG VIGPQRDEKF PNGLPLISSM AQTLTLRSSS QNSSDKPVAH VVANHQV

References

[1]	"Immediate early gene expression." Gerhauser I., Ulrich R., Baumgartner W. Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: SJL/J EMBL AAR00346.1. Tissue: Uterus EMBL AAR00346.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY423855 mRNA. Translation: AAR00346.1.
IPI	IPI00128861.
UniGene	Mm.1293
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q6TDG3.
Genome annotation databases
Ensembl	ENSMUST00000025263; ENSMUSP00000025263; ENSMUSG00000024401; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:104798. Tnf.
Phylogenomic databases
HOVERGEN	Q6TDG3.
Gene expression databases
ArrayExpress	Q6TDG3.
Bgee	Q6TDG3.
Genevestigator	Q6TDG3.
Family and domain databases
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q6TDG3_MOUSE

Accession

Primary (citable) accession number: Q6TDG3

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	November 3, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)