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Protein

Protein UL29/28

Gene

UL29

Organism
Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Contributes to activation of immediate-early gene expression.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein UL29/28
Gene namesi
Name:UL29
OrganismiHuman cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Taxonomic identifieri295027 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeBetaherpesvirinaeCytomegalovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000000938 Componenti: Genome

Subcellular locationi

  • Virion By similarity
  • Host nucleus By similarity
  • Host cytoplasm By similarity

  • Note: Expressed exclusively within the host nucleus in early times of infection and then present in both nucleus and cytoplasm at 72 hours post infection.By similarity

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm, Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004178601 – 700Protein UL29/28Add BLAST700

Expressioni

Keywords - Developmental stagei

Early protein

Interactioni

Subunit structurei

Interacts with UL38 and host HDAC1; these interactions are necessary for the HDAC1 interaction with UL38. Interacts with host MTA2 (By similarity).By similarity

Structurei

3D structure databases

SMRiQ6SWA3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi14 – 19Poly-Ser6

Sequence similaritiesi

Belongs to the herpesviridae US22 family.Curated

Phylogenomic databases

OrthoDBiVOG0900002Q.

Family and domain databases

InterProiView protein in InterPro
IPR003360. US22-like.
PfamiView protein in Pfam
PF02393. US22. 3 hits.

Sequencei

Sequence statusi: Complete.

Q6SWA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRRKGCSA ATASSSSSSP PSRLPLPGHA RRPRRKRCLV PEVFCTRDLA
60 70 80 90 100
DLCVRRDYEG LRRYLRRFEG SCVSLGWPSQ CIYVVGGEHS PHSLTEIDLE
110 120 130 140 150
HCQNDFFGEF RALHLIGTVS HATCRYQVFV DAYGAVFAYD AQEDCLYELA
160 170 180 190 200
SDLAGFFAKG MIRCDPVHES ICARLQPNVP LVHPDHRAEL CRRSRASARG
210 220 230 240 250
RYLRSLLAFR ELLACEDTAA RCAYVEAHRE AQLTLIWPEK HSLVLRTARD
260 270 280 290 300
LGLSASMLRR FQRSLYTREP VMPLGEIEGA EDKTFFHRVR ILCGDTGTVY
310 320 330 340 350
AALVGQDKLV RLSRDLRGFV RVGLALLIDD FRYESIGPVD RSSLYEANPE
360 370 380 390 400
LRLPFKKRRL VVGYFDSLSS LYLRGQPKFS SIWRGLRDAW THKRPKPRER
410 420 430 440 450
ASGVHLQRYV RATAGRWLPL CWPPLHGIML GDTQYFGVVR DHKTYRRFSC
460 470 480 490 500
LRQAGRLYFI GLVSVYECVP DANTAPEIWV SGHGHAFAYL PGEDKVYVLG
510 520 530 540 550
LSFGEFFENG LFAVYSFFER DYVDEIVEGA WFKHTFAGMY ELSQILHDRA
560 570 580 590 600
NLLRVCQLHA GSKIRLGGSP ACTFTFGSWN VAEADEANNF VIGVLEQAHF
610 620 630 640 650
VVIGWMEPVN KAVFMDAHGG IHVLLYGTML VKLAETLRGF IRQGSFWFRC
660 670 680 690 700
PRRFCFSPLD SSATVAAKPV SSHTSPAYDV SEYVFSGRSV LDSVSGTGAS
Length:700
Mass (Da):78,971
Last modified:March 24, 2009 - v2
Checksum:i845708E2851DDA72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY446894 Genomic DNA. Translation: AAR31593.2.
RefSeqiYP_081487.2. NC_006273.2.

Genome annotation databases

GeneIDi3077519.
KEGGivg:3077519.

Similar proteinsi

Entry informationi

Entry nameiUL298_HCMVM
AccessioniPrimary (citable) accession number: Q6SWA3
Secondary accession number(s): D2K3J7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2012
Last sequence update: March 24, 2009
Last modified: March 15, 2017
This is version 46 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families