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Protein

Capsid vertex component 1

Gene

CVC1

Organism
Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.UniRule annotation

GO - Biological processi

Keywordsi

Biological processViral genome packaging, Viral release from host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid vertex component 1UniRule annotation
Gene namesi
Name:CVC1UniRule annotation
Ordered Locus Names:UL93
OrganismiHuman cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Taxonomic identifieri295027 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeBetaherpesvirinaeCytomegalovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000000938 Componenti: Genome

Subcellular locationi

Q6SW50:
  • Virion UniRule annotation
  • Host nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004178491 – 594Capsid vertex component 1Add BLAST594

Expressioni

Keywords - Developmental stagei

Late protein

Interactioni

Subunit structurei

Interacts (via C-terminus) with capsid vertex component 2/CVC2.UniRule annotation

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi436 – 440Poly-Ala5

Sequence similaritiesi

Belongs to the herpesviridae CVC1 protein family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG09000094.

Family and domain databases

HAMAPiMF_04017. HSV_CVC1. 1 hit.
InterProiView protein in InterPro
IPR007640. UL17-like.
PfamiView protein in Pfam
PF04559. Herpes_UL17. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6SW50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METHLYSDLA FEARFADDEQ LPLHLVLDQE VLSNEEAETL RYVYYRNVDS
60 70 80 90 100
AGRSAGRVPS GDEDDAPASD DAEDAVGGDR AFDRERRTWQ RACFRVLPRP
110 120 130 140 150
LELLDYLRQS GLTVTLEKEQ RVRMFYAVFT TLGLRCPDNR LSGAQTLHLR
160 170 180 190 200
LVWPDGSYRD WEFLARDLLR EEMEANKRDR QHQLATTTNH RRRGGLRNNL
210 220 230 240 250
DNGSDRRLPE AAVASLETAV STPFFEIPNG AGTSSANGGG RFSNLEQRVA
260 270 280 290 300
RLLRGDEEFI YHAGPLEPPS KIRGHELVQL RLDVNPDLMY ATDPHDRDEV
310 320 330 340 350
ARTDEWKGAG VSRLREVWDV QHRVRLRVLW YVNSFWRSRE LSYDDHEVEL
360 370 380 390 400
YRALDAYRAR IAVEYVLIRA VRDEIYAVLR RDSGALPQRF ACHVPRNMSW
410 420 430 440 450
RVVWELCRHA LALWMDRADV RSCIIKALTP RLSRGAAAAA QRARRQRERS
460 470 480 490 500
APKPQELLFG PRNESGPPAE RTWYADVVRC VRTQVDLGVE VRAARCPRTG
510 520 530 540 550
LWIVRDRRGR LRRWLSQPEV CVLYVTPDLD FYWVLPGGFA VSSRVTLHGL
560 570 580 590
AQRALRDRFQ NFEAVLARGM HVEAGRQEPE TPRVSGRRLP FDDL
Length:594
Mass (Da):68,501
Last modified:July 5, 2004 - v1
Checksum:iF4EE0287D93B955D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY446894 Genomic DNA. Translation: AAR31644.1.
RefSeqiYP_081540.1. NC_006273.2.

Genome annotation databases

GeneIDi3077486.
KEGGivg:3077486.

Similar proteinsi

Entry informationi

Entry nameiCVC1_HCMVM
AccessioniPrimary (citable) accession number: Q6SW50
Secondary accession number(s): D2K3Q0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2012
Last sequence update: July 5, 2004
Last modified: October 25, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families