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Q6S3I0 (Q6S3I0_TORMA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Acetylcholine receptor beta subunit EMBL AAR29361.1
OrganismTorpedo marmorata (Marbled electric ray) EMBL AAR29361.1
Taxonomic identifier7788 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Chondrichthyes › Elasmobranchii › Squalea › Hypnosqualea › Pristiorajea › Batoidea › Torpediniformes › Torpedinoidei › Torpedinidae › Torpedo

Protein attributes

Sequence length493 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein By similarity RuleBase RU003585.

Sequence similarities

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification] RuleBase RU000687

Sequences

Sequence LengthMass (Da)Tools
Q6S3I0 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: BC64EE404C6418A1

FASTA49356,076
        10         20         30         40         50         60 
MEDVRRMALG LVVMMALALS GVGASVMEDT LLSVLFENYN PKVRPSQTVG DKVTVRVGLT 

        70         80         90        100        110        120 
LTSLLILNEK NEEMTTSVFL NLAWTDYRLQ WDPAAYEGIK DLSIPSDDVW QPDIVLMNNN 

       130        140        150        160        170        180 
DGSFEITLHV NVLVQHTGAV SWHPSAIYRS SCTIKVMYFP FDWQNCTMVF KSYTYDTSEV 

       190        200        210        220        230        240 
ILQHALDAKG EREVKEIMIN QDAFTENGQW SIEHKPSRKN WRSDDPSYED VTFYLIIQRK 

       250        260        270        280        290        300 
PLFYIVYTIV PCILISILAI LVFYLPPDAG EKMSLSISAL LALTVFLLLL ADKVPETSLS 

       310        320        330        340        350        360 
VPIIISYLMF IMILVAFSVI LSVVVLNLHH RSPNTHTMPN WIRQIFIETL PPFLWIQRPV 

       370        380        390        400        410        420 
TTPSPDSKPT IISRANDEYF IRKPAGDFVC PVDNARVAVQ PERLFSEMKW HLNGLTQPVT 

       430        440        450        460        470        480 
LPQDLKEAVE AIKYIAEQLE SASEFDDLKK DWQYVAMVAD RLFLYIFITM CSIGTFSIFL 

       490 
DASHNVPPDN PFA

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References

[1]"Phylogenetic conservation of disulfide-linked, dimeric acetylcholine receptor pentamers in southern ocean electric rays."
Tierney M.L., Osborn K.E., Milburn P.J., Stowell M.H., Howitt S.M.
J. Exp. Biol. 207:3581-3590(2004) [PubMed: 15339954] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Refined structure of the nicotinic acetylcholine receptor at 4A resolution."
Unwin N.
J. Mol. Biol. 346:967-989(2005) [PubMed: 15701510] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (4.00 ANGSTROMS) OF 25-493.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY472103 mRNA. Translation: AAR29361.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2BG9electron microscopy4.00B25-493[»]
ProteinModelPortalQ6S3I0.
SMRQ6S3I0. Positions 25-493.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG003756.

Family and domain databases

InterProIPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
IPR002394. Nicotinic_acetylcholine_rcpt.
[Graphical view]
Gene3DG3DSA:2.70.170.10. Neur_chan_lig_bd. 1 hit.
PANTHERPTHR18945. Neur_channel. 1 hit.
PfamPF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSPR00254. NICOTINICR.
PR00252. NRIONCHANNEL.
SUPFAMSSF90112. Neu_channel_TM. 1 hit.
SSF63712. Neur_chan_LBD. 1 hit.
TIGRFAMsTIGR00860. LIC. 1 hit.
PROSITEPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6S3I0_TORMA
AccessionPrimary (citable) accession number: Q6S3I0
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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