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Protein
Submitted name:

Acetylcholine receptor gamma subunit

Gene
N/A
Organism
Torpedo marmorata (Marbled electric ray)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotationImported
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Acetylcholine receptor gamma subunitImported
OrganismiTorpedo marmorata (Marbled electric ray)Imported
Taxonomic identifieri7788 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiBatoideaTorpediniformesTorpedinidaeTorpedo

Subcellular locationi

  • Cell junctionsynapsepostsynaptic cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation
  • Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei236 – 258HelicalSequence analysisAdd BLAST23
Transmembranei270 – 290HelicalSequence analysisAdd BLAST21
Transmembranei302 – 325HelicalSequence analysisAdd BLAST24
Transmembranei466 – 488HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500427970718 – 505Sequence analysisAdd BLAST488

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi144 ↔ 158Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BG9electron microscopy4.00E18-493[»]
4AQ5electron microscopy6.20E18-505[»]
4AQ9electron microscopy6.20E18-505[»]
4BOGelectron microscopy50.003/E/J/O/T/Y1-505[»]
4BOIelectron microscopy41.00E1-505[»]
4BONelectron microscopy40.00E1-505[»]
4BOOelectron microscopy42.00E1-505[»]
4BORelectron microscopy42.00E1-505[»]
4BOTelectron microscopy42.00E1-505[»]
ProteinModelPortaliQ6S3H9.
SMRiQ6S3H9.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6S3H9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 235Neur_chan_LBDInterPro annotationAdd BLAST215
Domaini242 – 483Neur_chan_membInterPro annotationAdd BLAST242

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG003756.

Family and domain databases

Gene3Di2.70.170.10. 1 hit.
InterProiView protein in InterPro
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
IPR002394. Nicotinic_acetylcholine_rcpt.
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiView protein in Pfam
PF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
PRINTSiPR00254. NICOTINICR.
PR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
PROSITEiView protein in PROSITE
PS00236. NEUROTR_ION_CHANNEL. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6S3H9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLTLLLIIC LALEVRSNEE GRLIEKLLGD YDKRIKPAKT LDHVIDVTLK
60 70 80 90 100
LTLTNLISLN EKEEALTTNV WIEIQWNDYR LSWNTSEYEG IDLVRIPSEL
110 120 130 140 150
LWLPDVVLEN NVDGQFEVAY YANVLVYNDG SMYWLPPAIY RSTCPIAVTY
160 170 180 190 200
FPFDWQNCSL VFRSQTYNAH EVNLQLSAEE GEVVEWIHID PEDFTENGEW
210 220 230 240 250
TIRHRPAKKN YNWQLTKDDI DFQEIIFFLI IQRKPLFYII NIIAPCVLIS
260 270 280 290 300
SLVVLVYFLP AQAGGQKCTL SISVLLAQTI FLFLIAQKVP ETSLNVPLIG
310 320 330 340 350
KYLIFVMFVS LVIVTNCVIV LNVSLRTPNT HSLSEKIKHL FLEFLPKYLG
360 370 380 390 400
MHLEPSEETP EKPQPRRRSS FGIMIKAEEY ILKKPRSELM FEEQKDRHGL
410 420 430 440 450
KRVNKMTSDI DIGTTVDLYK DLANFAPEIK SCVEACNFIA KSTKEQNDSG
460 470 480 490 500
SENENWVLIG KVIDKACFWI ALLLFSLGTL AIFLTGHLNQ VPEFPFPGDP

RKYVP
Length:505
Mass (Da):58,061
Last modified:July 5, 2004 - v1
Checksum:iF57B2D01312E51A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY472104 mRNA. Translation: AAR29362.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ6S3H9_TORMA
AccessioniPrimary (citable) accession number: Q6S3H9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 5, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources