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Protein

Brain-specific homeobox protein homolog

Gene

BSX

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

DNA binding protein that function as transcriptional activator. May play a role in the determination and function of cell types in the brain.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi110 – 170HomeoboxPROSITE-ProRule annotationAdd BLAST61

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Brain-specific homeobox protein homolog
Gene namesi
Name:BSXImported
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 24

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000488431 – 233Brain-specific homeobox protein homologAdd BLAST233

Proteomic databases

PaxDbiQ6RFL5

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000010513

Structurei

3D structure databases

ProteinModelPortaliQ6RFL5
SMRiQ6RFL5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi68 – 109His-richAdd BLAST42

Sequence similaritiesi

Belongs to the distal-less homeobox family.Sequence analysis

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0491 Eukaryota
ENOG4111UAT LUCA
GeneTreeiENSGT00910000143987
HOGENOMiHOG000231924
HOVERGENiHBG050738
InParanoidiQ6RFL5
OMAiGMQMPAL
OrthoDBiEOG091G0QT3
PhylomeDBiQ6RFL5
TreeFamiTF350735

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PRINTSiPR00024 HOMEOBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6RFL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLNFTSPVH PVPAPRPTSF FIEDILLHKP KPLREVPPEH FAGSLASRVP
60 70 80 90 100
LLDYGYPLMP APALLAPHPH PALHKPEHHH HHPYFLTTSG VPVPALFPHH
110 120 130 140 150
AHAELPGKHC RRRKARTVFS DSQLSGLEKR FEIQRYLSTP ERVELATALS
160 170 180 190 200
LSETQVKTWF QNRRMKHKKQ LRKSQDDPIH EENREQSSPE PELPEPAAAE
210 220 230
PRKGPPGPFL LQDPEDEVDI LEEGDILAAP HRL
Length:233
Mass (Da):26,452
Last modified:July 5, 2004 - v1
Checksum:i7CF5E9DA4953AB6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY500594 mRNA Translation: AAR89086.1
RefSeqiNP_989843.1, NM_204512.1
UniGeneiGga.9478

Genome annotation databases

EnsembliENSGALT00000010527; ENSGALP00000010513; ENSGALG00000006515
GeneIDi395183
KEGGigga:395183

Similar proteinsi

Entry informationi

Entry nameiBSH_CHICK
AccessioniPrimary (citable) accession number: Q6RFL5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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