Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6RFL5

- BSH_CHICK

UniProt

Q6RFL5 - BSH_CHICK

Protein

Brain-specific homeobox protein homolog

Gene

BSX

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    DNA binding protein that function as transcriptional activator. May play a role in the determination and function of cell types in the brain.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi110 – 17061HomeoboxPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: Ensembl
    2. sequence-specific DNA binding transcription factor activity Source: Ensembl

    GO - Biological processi

    1. brain development Source: UniProtKB
    2. eating behavior Source: Ensembl
    3. locomotory behavior Source: Ensembl
    4. mammary gland involution Source: Ensembl
    5. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    6. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Brain-specific homeobox protein homolog
    Gene namesi
    Name:BSXImported
    OrganismiGallus gallus (Chicken)
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
    ProteomesiUP000000539: Chromosome 24

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. nucleus Source: UniProtKB-SubCell
    3. transcription factor complex Source: Ensembl

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 233233Brain-specific homeobox protein homologPRO_0000048843Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi9031.ENSGALP00000010513.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6RFL5.
    SMRiQ6RFL5. Positions 106-169.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi68 – 10942His-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the distal-less homeobox family.Sequence Analysis
    Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Homeobox

    Phylogenomic databases

    eggNOGiNOG242366.
    GeneTreeiENSGT00740000114906.
    HOGENOMiHOG000231924.
    HOVERGENiHBG050738.
    InParanoidiQ6RFL5.
    OMAiLHKPEHH.
    OrthoDBiEOG7QVM51.
    PhylomeDBiQ6RFL5.
    TreeFamiTF350735.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    InterProiIPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR020479. Homeobox_metazoa.
    IPR009057. Homeodomain-like.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    [Graphical view]
    PRINTSiPR00024. HOMEOBOX.
    SMARTiSM00389. HOX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6RFL5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNLNFTSPVH PVPAPRPTSF FIEDILLHKP KPLREVPPEH FAGSLASRVP    50
    LLDYGYPLMP APALLAPHPH PALHKPEHHH HHPYFLTTSG VPVPALFPHH 100
    AHAELPGKHC RRRKARTVFS DSQLSGLEKR FEIQRYLSTP ERVELATALS 150
    LSETQVKTWF QNRRMKHKKQ LRKSQDDPIH EENREQSSPE PELPEPAAAE 200
    PRKGPPGPFL LQDPEDEVDI LEEGDILAAP HRL 233
    Length:233
    Mass (Da):26,452
    Last modified:July 5, 2004 - v1
    Checksum:i7CF5E9DA4953AB6C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY500594 mRNA. Translation: AAR89086.1.
    RefSeqiNP_989843.1. NM_204512.1.
    UniGeneiGga.9478.

    Genome annotation databases

    EnsembliENSGALT00000010527; ENSGALP00000010513; ENSGALG00000006515.
    GeneIDi395183.
    KEGGigga:395183.

    Cross-referencesi

    Web resourcesi

    Protein Spotlight

    Of fidgets and food - Issue 85 of August 2007

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY500594 mRNA. Translation: AAR89086.1 .
    RefSeqi NP_989843.1. NM_204512.1.
    UniGenei Gga.9478.

    3D structure databases

    ProteinModelPortali Q6RFL5.
    SMRi Q6RFL5. Positions 106-169.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9031.ENSGALP00000010513.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSGALT00000010527 ; ENSGALP00000010513 ; ENSGALG00000006515 .
    GeneIDi 395183.
    KEGGi gga:395183.

    Organism-specific databases

    CTDi 390259.

    Phylogenomic databases

    eggNOGi NOG242366.
    GeneTreei ENSGT00740000114906.
    HOGENOMi HOG000231924.
    HOVERGENi HBG050738.
    InParanoidi Q6RFL5.
    OMAi LHKPEHH.
    OrthoDBi EOG7QVM51.
    PhylomeDBi Q6RFL5.
    TreeFami TF350735.

    Miscellaneous databases

    NextBioi 20815273.
    PROi Q6RFL5.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    InterProi IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR020479. Homeobox_metazoa.
    IPR009057. Homeodomain-like.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    [Graphical view ]
    PRINTSi PR00024. HOMEOBOX.
    SMARTi SM00389. HOX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of vertebrate homologs of the Drosophila brain-specific homeobox gene."
      Assimacopoulos S., Ragsdale C.W.
      Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: ForebrainImported.

    Entry informationi

    Entry nameiBSH_CHICK
    AccessioniPrimary (citable) accession number: Q6RFL5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 31, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Protein Spotlight
      Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3