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Reviewed, UniProtKB/Swiss-Prot Q6RFL5 (BSH_CHICK)

Last modified November 24, 2009. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Web resources · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Brain-specific homeobox protein homolog
Gene names
Name: BSX
OrganismGallus gallus (Chicken)
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Function

DNA binding protein that function as transcriptional activator By similarity. May play a role in the determination and function of cell types in the brain By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the distal-less homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionActivator
Gene Ontology (GO)
   Biological processbrain development

Inferred from sequence or structural similarity. Source: UniProtKB

transcription

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 233233Brain-specific homeobox protein homolog
PRO_0000048843

Regions

DNA binding110 – 17061Homeobox
Compositional bias68 – 10942His-rich

Sequences

Sequence LengthMass (Da)Tools
Q6RFL5-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 7CF5E9DA4953AB6C

FASTA23326,452
        10         20         30         40         50         60 
MNLNFTSPVH PVPAPRPTSF FIEDILLHKP KPLREVPPEH FAGSLASRVP LLDYGYPLMP 

        70         80         90        100        110        120 
APALLAPHPH PALHKPEHHH HHPYFLTTSG VPVPALFPHH AHAELPGKHC RRRKARTVFS 

       130        140        150        160        170        180 
DSQLSGLEKR FEIQRYLSTP ERVELATALS LSETQVKTWF QNRRMKHKKQ LRKSQDDPIH 

       190        200        210        220        230 
EENREQSSPE PELPEPAAAE PRKGPPGPFL LQDPEDEVDI LEEGDILAAP HRL 

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References

[1]"Identification of vertebrate homologs of the Drosophila brain-specific homeobox gene."
Assimacopoulos S., Ragsdale C.W.
Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Forebrain.

Web resources

Protein Spotlight

Of fidgets and food - Issue 85 of August 2007

Cross-references

Sequence databases

AY500594 mRNA. Translation: AAR89086.1.
IPIIPI00581246.
RefSeqNP_989843.1.
UniGeneGga.9478

3D structure databases

ModBaseSearch...

Genome annotation databases

EnsemblENSGALT00000010527; ENSGALP00000010513; ENSGALG00000006515; Gallus gallus. [Genome view]
GeneID395183.
KEGGgga:395183.

Organism-specific databases

CTD395183.

Phylogenomic databases

HOGENOMQ6RFL5.
HOVERGENQ6RFL5.
OMAILAPHPH
OrthoDBEOG9QC3QS

Family and domain databases

InterProIPR001356. Homeobox.
IPR017970. Homeobox_CS.
IPR020479. Homeobox_region.
IPR009057. Homeodomain-like.
IPR012287. Homeodomain-rel.
[Graphical view]
Gene3DG3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
PfamPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
PROSITEPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBSH_CHICK
AccessionPrimary (citable) accession number: Q6RFL5
Entry history
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 5, 2004
Last modified: November 24, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Web resources · Cross-references · Entry information · Relevant documents