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Protein
Submitted name:

Microcephalin

Gene

MCPH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
MicrocephalinImported
Gene namesi
Name:MCPH1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ6RBQ8.

Expressioni

Gene expression databases

BgeeiQ6RBQ8.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000342924.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 3939BRCTInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG4362. Eukaryota.
ENOG41120NI. LUCA.

Family and domain databases

Gene3Di3.40.50.10190. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR022047. Microcephalin-like.
[Graphical view]
PANTHERiPTHR14625. PTHR14625. 1 hit.
PfamiPF12738. PTCB-BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF52113. SSF52113. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6RBQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
VSKTFNKQVT HVIFKDGYQS TWDKAQKRGV KLVSVLWVE
Length:39
Mass (Da):4,551
Last modified:July 5, 2004 - v1
Checksum:i8C08F249C14D7817
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei39 – 391Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY505637 Genomic DNA. Translation: AAS86515.1.
AY505638 Genomic DNA. Translation: AAS86516.1.
AY505639 Genomic DNA. Translation: AAS86517.1.
AY505640 Genomic DNA. Translation: AAS86518.1.
AY505641 Genomic DNA. Translation: AAS86519.1.
AY505642 Genomic DNA. Translation: AAS86520.1.
AY505643 Genomic DNA. Translation: AAS86521.1.
AY505644 Genomic DNA. Translation: AAS86522.1.
AY505645 Genomic DNA. Translation: AAS86523.1.
AY505646 Genomic DNA. Translation: AAS86524.1.
AY505647 Genomic DNA. Translation: AAS86525.1.
AY505648 Genomic DNA. Translation: AAS86526.1.
AY505649 Genomic DNA. Translation: AAS86527.1.
AY505650 Genomic DNA. Translation: AAS86528.1.
AY505651 Genomic DNA. Translation: AAS86529.1.
AY505652 Genomic DNA. Translation: AAS86530.1.
AY505653 Genomic DNA. Translation: AAS86531.1.
AY505654 Genomic DNA. Translation: AAS86532.1.
AY505655 Genomic DNA. Translation: AAS86533.1.
AY505656 Genomic DNA. Translation: AAS86534.1.
AY505657 Genomic DNA. Translation: AAS86535.1.
AY505658 Genomic DNA. Translation: AAS86536.1.
AY505659 Genomic DNA. Translation: AAS86537.1.
AY505660 Genomic DNA. Translation: AAS86538.1.
AY505661 Genomic DNA. Translation: AAS86539.1.
AY505662 Genomic DNA. Translation: AAS86540.1.
AY505663 Genomic DNA. Translation: AAS86541.1.
AY505664 Genomic DNA. Translation: AAS86542.1.
AY505665 Genomic DNA. Translation: AAS86543.1.
AY505666 Genomic DNA. Translation: AAS86544.1.
AY505667 Genomic DNA. Translation: AAS86545.1.
AY505668 Genomic DNA. Translation: AAS86546.1.
AY505669 Genomic DNA. Translation: AAS86547.1.
AY505670 Genomic DNA. Translation: AAS86548.1.
AY505671 Genomic DNA. Translation: AAS86549.1.
AY505672 Genomic DNA. Translation: AAS86550.1.
AY505673 Genomic DNA. Translation: AAS86551.1.
AY505674 Genomic DNA. Translation: AAS86552.1.
AY505675 Genomic DNA. Translation: AAS86553.1.
AY505676 Genomic DNA. Translation: AAS86554.1.
AY505677 Genomic DNA. Translation: AAS86555.1.
UniGeneiHs.593807.
Hs.656769.
Hs.708770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY505637 Genomic DNA. Translation: AAS86515.1.
AY505638 Genomic DNA. Translation: AAS86516.1.
AY505639 Genomic DNA. Translation: AAS86517.1.
AY505640 Genomic DNA. Translation: AAS86518.1.
AY505641 Genomic DNA. Translation: AAS86519.1.
AY505642 Genomic DNA. Translation: AAS86520.1.
AY505643 Genomic DNA. Translation: AAS86521.1.
AY505644 Genomic DNA. Translation: AAS86522.1.
AY505645 Genomic DNA. Translation: AAS86523.1.
AY505646 Genomic DNA. Translation: AAS86524.1.
AY505647 Genomic DNA. Translation: AAS86525.1.
AY505648 Genomic DNA. Translation: AAS86526.1.
AY505649 Genomic DNA. Translation: AAS86527.1.
AY505650 Genomic DNA. Translation: AAS86528.1.
AY505651 Genomic DNA. Translation: AAS86529.1.
AY505652 Genomic DNA. Translation: AAS86530.1.
AY505653 Genomic DNA. Translation: AAS86531.1.
AY505654 Genomic DNA. Translation: AAS86532.1.
AY505655 Genomic DNA. Translation: AAS86533.1.
AY505656 Genomic DNA. Translation: AAS86534.1.
AY505657 Genomic DNA. Translation: AAS86535.1.
AY505658 Genomic DNA. Translation: AAS86536.1.
AY505659 Genomic DNA. Translation: AAS86537.1.
AY505660 Genomic DNA. Translation: AAS86538.1.
AY505661 Genomic DNA. Translation: AAS86539.1.
AY505662 Genomic DNA. Translation: AAS86540.1.
AY505663 Genomic DNA. Translation: AAS86541.1.
AY505664 Genomic DNA. Translation: AAS86542.1.
AY505665 Genomic DNA. Translation: AAS86543.1.
AY505666 Genomic DNA. Translation: AAS86544.1.
AY505667 Genomic DNA. Translation: AAS86545.1.
AY505668 Genomic DNA. Translation: AAS86546.1.
AY505669 Genomic DNA. Translation: AAS86547.1.
AY505670 Genomic DNA. Translation: AAS86548.1.
AY505671 Genomic DNA. Translation: AAS86549.1.
AY505672 Genomic DNA. Translation: AAS86550.1.
AY505673 Genomic DNA. Translation: AAS86551.1.
AY505674 Genomic DNA. Translation: AAS86552.1.
AY505675 Genomic DNA. Translation: AAS86553.1.
AY505676 Genomic DNA. Translation: AAS86554.1.
AY505677 Genomic DNA. Translation: AAS86555.1.
UniGeneiHs.593807.
Hs.656769.
Hs.708770.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000342924.

Proteomic databases

PaxDbiQ6RBQ8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG4362. Eukaryota.
ENOG41120NI. LUCA.

Miscellaneous databases

ChiTaRSiMCPH1. human.

Gene expression databases

BgeeiQ6RBQ8.

Family and domain databases

Gene3Di3.40.50.10190. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR022047. Microcephalin-like.
[Graphical view]
PANTHERiPTHR14625. PTHR14625. 1 hit.
PfamiPF12738. PTCB-BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF52113. SSF52113. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Wang Y., Su B.
    Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Molecular evolution of microcephalin, a gene determining human brain size."
    Wang Y.Q., Su B.
    Hum. Mol. Genet. 13:1131-1137(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6RBQ8_HUMAN
AccessioniPrimary (citable) accession number: Q6RBQ8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 16, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.