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Protein
Submitted name:

Microcephalin

Gene

MCPH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
MicrocephalinImported
Gene namesi
Name:MCPH1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiQ6RBQ8.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000342924.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 3939BRCTInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG4362. Eukaryota.
ENOG41120NI. LUCA.

Family and domain databases

Gene3Di3.40.50.10190. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR022047. Microcephalin-like.
[Graphical view]
PANTHERiPTHR14625. PTHR14625. 1 hit.
PfamiPF12738. PTCB-BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF52113. SSF52113. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6RBQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
VSKTFNKQVT HVIFKDGYQS TWDKAQKRGV KLVSVLWVE
Length:39
Mass (Da):4,551
Last modified:July 5, 2004 - v1
Checksum:i8C08F249C14D7817
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei39 – 391Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY505637 Genomic DNA. Translation: AAS86515.1.
AY505638 Genomic DNA. Translation: AAS86516.1.
AY505639 Genomic DNA. Translation: AAS86517.1.
AY505640 Genomic DNA. Translation: AAS86518.1.
AY505641 Genomic DNA. Translation: AAS86519.1.
AY505642 Genomic DNA. Translation: AAS86520.1.
AY505643 Genomic DNA. Translation: AAS86521.1.
AY505644 Genomic DNA. Translation: AAS86522.1.
AY505645 Genomic DNA. Translation: AAS86523.1.
AY505646 Genomic DNA. Translation: AAS86524.1.
AY505647 Genomic DNA. Translation: AAS86525.1.
AY505648 Genomic DNA. Translation: AAS86526.1.
AY505649 Genomic DNA. Translation: AAS86527.1.
AY505650 Genomic DNA. Translation: AAS86528.1.
AY505651 Genomic DNA. Translation: AAS86529.1.
AY505652 Genomic DNA. Translation: AAS86530.1.
AY505653 Genomic DNA. Translation: AAS86531.1.
AY505654 Genomic DNA. Translation: AAS86532.1.
AY505655 Genomic DNA. Translation: AAS86533.1.
AY505656 Genomic DNA. Translation: AAS86534.1.
AY505657 Genomic DNA. Translation: AAS86535.1.
AY505658 Genomic DNA. Translation: AAS86536.1.
AY505659 Genomic DNA. Translation: AAS86537.1.
AY505660 Genomic DNA. Translation: AAS86538.1.
AY505661 Genomic DNA. Translation: AAS86539.1.
AY505662 Genomic DNA. Translation: AAS86540.1.
AY505663 Genomic DNA. Translation: AAS86541.1.
AY505664 Genomic DNA. Translation: AAS86542.1.
AY505665 Genomic DNA. Translation: AAS86543.1.
AY505666 Genomic DNA. Translation: AAS86544.1.
AY505667 Genomic DNA. Translation: AAS86545.1.
AY505668 Genomic DNA. Translation: AAS86546.1.
AY505669 Genomic DNA. Translation: AAS86547.1.
AY505670 Genomic DNA. Translation: AAS86548.1.
AY505671 Genomic DNA. Translation: AAS86549.1.
AY505672 Genomic DNA. Translation: AAS86550.1.
AY505673 Genomic DNA. Translation: AAS86551.1.
AY505674 Genomic DNA. Translation: AAS86552.1.
AY505675 Genomic DNA. Translation: AAS86553.1.
AY505676 Genomic DNA. Translation: AAS86554.1.
AY505677 Genomic DNA. Translation: AAS86555.1.
UniGeneiHs.593807.
Hs.656769.
Hs.708770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY505637 Genomic DNA. Translation: AAS86515.1.
AY505638 Genomic DNA. Translation: AAS86516.1.
AY505639 Genomic DNA. Translation: AAS86517.1.
AY505640 Genomic DNA. Translation: AAS86518.1.
AY505641 Genomic DNA. Translation: AAS86519.1.
AY505642 Genomic DNA. Translation: AAS86520.1.
AY505643 Genomic DNA. Translation: AAS86521.1.
AY505644 Genomic DNA. Translation: AAS86522.1.
AY505645 Genomic DNA. Translation: AAS86523.1.
AY505646 Genomic DNA. Translation: AAS86524.1.
AY505647 Genomic DNA. Translation: AAS86525.1.
AY505648 Genomic DNA. Translation: AAS86526.1.
AY505649 Genomic DNA. Translation: AAS86527.1.
AY505650 Genomic DNA. Translation: AAS86528.1.
AY505651 Genomic DNA. Translation: AAS86529.1.
AY505652 Genomic DNA. Translation: AAS86530.1.
AY505653 Genomic DNA. Translation: AAS86531.1.
AY505654 Genomic DNA. Translation: AAS86532.1.
AY505655 Genomic DNA. Translation: AAS86533.1.
AY505656 Genomic DNA. Translation: AAS86534.1.
AY505657 Genomic DNA. Translation: AAS86535.1.
AY505658 Genomic DNA. Translation: AAS86536.1.
AY505659 Genomic DNA. Translation: AAS86537.1.
AY505660 Genomic DNA. Translation: AAS86538.1.
AY505661 Genomic DNA. Translation: AAS86539.1.
AY505662 Genomic DNA. Translation: AAS86540.1.
AY505663 Genomic DNA. Translation: AAS86541.1.
AY505664 Genomic DNA. Translation: AAS86542.1.
AY505665 Genomic DNA. Translation: AAS86543.1.
AY505666 Genomic DNA. Translation: AAS86544.1.
AY505667 Genomic DNA. Translation: AAS86545.1.
AY505668 Genomic DNA. Translation: AAS86546.1.
AY505669 Genomic DNA. Translation: AAS86547.1.
AY505670 Genomic DNA. Translation: AAS86548.1.
AY505671 Genomic DNA. Translation: AAS86549.1.
AY505672 Genomic DNA. Translation: AAS86550.1.
AY505673 Genomic DNA. Translation: AAS86551.1.
AY505674 Genomic DNA. Translation: AAS86552.1.
AY505675 Genomic DNA. Translation: AAS86553.1.
AY505676 Genomic DNA. Translation: AAS86554.1.
AY505677 Genomic DNA. Translation: AAS86555.1.
UniGeneiHs.593807.
Hs.656769.
Hs.708770.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000342924.

Proteomic databases

PeptideAtlasiQ6RBQ8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG4362. Eukaryota.
ENOG41120NI. LUCA.

Miscellaneous databases

ChiTaRSiMCPH1. human.

Family and domain databases

Gene3Di3.40.50.10190. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR022047. Microcephalin-like.
[Graphical view]
PANTHERiPTHR14625. PTHR14625. 1 hit.
PfamiPF12738. PTCB-BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF52113. SSF52113. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Wang Y., Su B.
    Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Molecular evolution of microcephalin, a gene determining human brain size."
    Wang Y.Q., Su B.
    Hum. Mol. Genet. 13:1131-1137(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6RBQ8_HUMAN
AccessioniPrimary (citable) accession number: Q6RBQ8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 6, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.