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Protein
Submitted name:

Lymphocyte antigen CD4

Gene

CD4

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Lymphocyte antigen CD4Imported
Gene namesi
Name:CD4Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei397 – 422HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501014248725 – 457Sequence analysisAdd BLAST433

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 122Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST103
Domaini138 – 196Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST59

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK9F. Eukaryota.
ENOG410YWI4. LUCA.
HOGENOMiHOG000008696.
HOVERGENiHBG005281.
KOiK06454.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
InterProiView protein in InterPro
IPR000973. CD4.
IPR015274. CD4-extracel.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR008424. Ig_C2-set.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR013151. Immunoglobulin.
IPR021963. Tcell_CD4_Cterm.
PANTHERiPTHR11422:SF3. PTHR11422:SF3. 1 hit.
PfamiView protein in Pfam
PF05790. C2-set. 2 hits.
PF09191. CD4-extracel. 1 hit.
PF00047. ig. 1 hit.
PF12104. Tcell_CD4_C. 1 hit.
PRINTSiPR00692. CD4TCANTIGEN.
SMARTiView protein in SMART
SM00409. IG. 3 hits.
SM00406. IGv. 1 hit.
SUPFAMiSSF48726. SSF48726. 4 hits.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 2 hits.

Sequencei

Sequence statusi: Complete.

Q6R3N4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPGTSLRHL FLVLQLAMLP AASGTQEKYL VLGKAGDLAE LPCHSSQKKN
60 70 80 90 100
LPFNWKNSNQ TKILGGHGSF WHTASVTELT SRLDSKKNMW DHGSFPLIIK
110 120 130 140 150
NLEVTDSGIY ICEVEDKRIE VQLLVFRLTA SVTRVLLGQS LTLTLEGPSG
160 170 180 190 200
SHPTVQWKGP GNKSKNDVKS LLLPQVGLED SGLWTCTVSQ DQKTLVFRSN
210 220 230 240 250
IFVLAFQKVP STVYVKEGDQ VALSFPLTFE AESLSGELMW RQTKGASSPQ
260 270 280 290 300
SWITFSLKDR KVTVQKSLQN LKLRMAEKLP LQITLLQALP QYAGSGNLTL
310 320 330 340 350
VLPEGRLHRE VNLVVMRATQ SKNEVTCEVL GPTPPKVVLS LKLGNQSMKV
360 370 380 390 400
SDQQKLVTVL DPEAGMWRCL LRDKDKVLLE SQVEVLPTAF TRAWPELLAS
410 420 430 440 450
VIGGIIGLLF LAGFCIACVK CWHRRRRAER MSQIKRLLSE KKTCQCAHRQ

QKNYSLT
Length:457
Mass (Da):50,954
Last modified:May 24, 2005 - v2
Checksum:iF470CACB5E73678A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY515292 mRNA. Translation: AAR99808.2.
AY590799 mRNA. Translation: AAT52342.1.
UniGeneiSsc.16239.

Genome annotation databases

KEGGissc:404704.

Similar proteinsi

Entry informationi

Entry nameiQ6R3N4_PIG
AccessioniPrimary (citable) accession number: Q6R3N4
Secondary accession number(s): Q6GYR3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: May 24, 2005
Last modified: July 5, 2017
This is version 89 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)