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Protein
Submitted name:

Neuronal cell adhesion molecule short isoform

Gene

Nrcam

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ankyrin binding Source: MGI
  2. protein binding involved in heterotypic cell-cell adhesion Source: MGI

GO - Biological processi

  1. angiogenesis Source: Ensembl
  2. clustering of voltage-gated sodium channels Source: MGI
  3. heterotypic cell-cell adhesion Source: GOC
  4. neuronal action potential propagation Source: MGI
  5. protein localization Source: MGI
  6. regulation of neuron projection development Source: MGI
  7. retinal ganglion cell axon guidance Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Neuronal cell adhesion molecule short isoformImported
Gene namesi
Name:NrcamImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:104750. Nrcam.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: MGI
  2. plasma membrane Source: MGI
  3. synapse Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ6QRP1.
ExpressionAtlasiQ6QRP1. baseline and differential.
GenevestigatoriQ6QRP1.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG063178.
KOiK06756.

Family and domain databases

InterProiIPR026966. Neurofascin/L1/NrCAM_C.
[Graphical view]
PfamiPF13882. Bravo_FIGEY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6QRP1-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MPGTAYKVRV GAEGDSGFVS SEDVFETGPA MASRQVDIAT QGWFIGLMCA
60 70 80 90 100
VALLILILLI VCFIRRNKGG KYPVKEKEDA HADPEIQPMK EDDGTFGEYS
110 120 130 140 150
DAEDHKPLKK GSRTPSDRTV KKEDSDDSLV DYGEGVNGQF NEDGSFIGQY
160 170
SGKKEKEPAE GNESSEAPSP VNAMNSFV
Length:178
Mass (Da):19,303
Last modified:July 5, 2004 - v1
Checksum:i505F0D8BEBDC1249
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY528242 mRNA. Translation: AAS48508.1.
RefSeqiNP_001139503.1. NM_001146031.1.
NP_795904.3. NM_176930.4.
UniGeneiMm.208439.

Genome annotation databases

GeneIDi319504.
KEGGimmu:319504.
UCSCiuc007nlz.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY528242 mRNA. Translation: AAS48508.1.
RefSeqiNP_001139503.1. NM_001146031.1.
NP_795904.3. NM_176930.4.
UniGeneiMm.208439.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi319504.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi319504.
KEGGimmu:319504.
UCSCiuc007nlz.2. mouse.

Organism-specific databases

CTDi4897.
MGIiMGI:104750. Nrcam.

Phylogenomic databases

HOVERGENiHBG063178.
KOiK06756.

Miscellaneous databases

ChiTaRSiNrcam. mouse.
NextBioi394866.
SOURCEiSearch...

Gene expression databases

BgeeiQ6QRP1.
ExpressionAtlasiQ6QRP1. baseline and differential.
GenevestigatoriQ6QRP1.

Family and domain databases

InterProiIPR026966. Neurofascin/L1/NrCAM_C.
[Graphical view]
PfamiPF13882. Bravo_FIGEY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Liu Q.-R., Uhl G.R.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  2. "NrCAM in Addiction Vulnerability: Positional Cloning, Drug-Regulation, Haplotype-Specific Expression, and Altered Drug Reward in Knockout Mice."
    Ishiguro H., Liu Q.R., Gong J.P., Hall F.S., Ujike H., Morales M., Sakurai T., Grumet M., Uhl G.R.
    Neuropsychopharmacology 0:0-0(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ6QRP1_MOUSE
AccessioniPrimary (citable) accession number: Q6QRP1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 4, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.